【Animal Modeling】-Application of Nile Red Tracer Nanoparticles in In Vivo Imaging of Tumor-bearing Nude Mice

To encapsulate Nile Red into nano-formulations, and use its fluorescence properties to investigate the tumor targeting and tissue distribution of nano-formulations in tumor-bearing mice...

2022-03-22

【Animal Modeling】-Experimental Study on Coptis Rhizoma Polysaccharide Relieves Kidney Injury in Diabetic Rats by Inhibiting Oxidative Stress and Inflammatory Response

To study the protective effect and potential mechanism of Coptis chinensis polysaccharide on renal injury in diabetic rats...

2022-03-22

【Animal Modeling】-Observation of neurotoxicological effects of flame retardant TCPP exposure in mice and related mechanisms

To investigate the neurotoxicological effects of flame retardant TCPP exposure in mice and related mechanisms...

2022-03-22

【Animal modeling】-3M tissue glue and electrocoagulation for hemostasis in nephrectomy in uremic rats

To compare the application of two hemostatic methods in rat uremic model...

2022-03-22

【Animal modeling】-Effect of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats

To evaluate the effects of metformin, aerobic exercise and the combined intervention of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats...

2022-03-22

【Animal modeling】-The neuroprotective effect of artesunate on experimental autoimmune encephalomyelitis mice and the effect of autophagy

To investigate the neuroprotective effect and autophagy of artesunate on experimental autoimmune encephalomyelitis (EAE) mice...

2022-03-22

【Animal modeling】-Experimental observation of porcine circovirus type 3 infection in BALB/c mice

To study the infection of porcine circovirus type 3 in BALB/c mice...

2022-03-22

【Animal modeling】-Effect of Fujiutie ointment on the expression of NGF/TrKA and related inflammatory factors in asthmatic mice

To observe the effect of the preparation \"Fujiu Tie Gao\" of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine on serum interleukin-4, interferon γ, related immunoglobulin E cytokines, nerve growth factor and t...

2022-03-22

【Animal modeling】-Effect of high expression of Axl on subcutaneous tumorigenesis of gastric cancer cells in nude mice

To preliminarily explore the effect of high Axl expression on subcutaneous tumorigenesis of gastric cancer cells in nude mice...

2022-03-21

【Animal Modeling】-The hypoglycemic effect of the polysaccharide of the mushroom on streptozotocin-induced diabetic rats

To explore the effect of polysaccharides from the mushroom on the hypoglycemic effect of streptozotocin-induced type 1 diabetes (DM) rats...

2022-03-21

【Animal modeling】-P38MAPK changes and immunoregulatory effects in diarrhea-predominant irritable bowel syndrome rats

To investigate the immunoregulatory effect of p38MAPK signaling in diarrhea-predominant irritable bowel syndrome rats...

2022-03-21

【Animal modeling】-Anti-atherosclerosis and cardioprotective effects of perilla seed extract in ApoE-/- mice

To study the effect and molecular mechanism of perilla seed oily extract (PSO) on reducing plaque formation and cardioprotection in ApoE-/- mice...

2022-03-21

【Animal Modeling】-Comparison of intravenous injection needle and self-made PE-50 needle in the measurement of intracavernous pressure in rats

To investigate the method of electrical stimulation of the cavernosal nerve of the penis to detect the intracavernous pressure, and to compare the differences between the two catheter materials (PE-50 tube needle and intravenous infusion needle) for ...

2022-03-21

【Animal modeling】-Effect of busulfan on peripheral blood cells and bone marrow cells of type 2 diabetic KKAy mice

To observe the damage effect of busulfan on the hematopoietic function of KK/upj-Ay/J (KKAy) mice, a model of type 2 diabetes mellitus, and to compare with the control C57BL/6J (B6) mice...

2022-03-21

【Animal Model】-Effects of nicotine on changes in pain threshold plasticity and cardioprotection in rats with myocardial infarction

To observe the plastic changes of pain threshold in rats with myocardial infarction, and to explore the effect of nicotine on visceral pain and whether it has a protective effect on ischemic myocardium...

2022-03-21

【Animal modeling】-The dose-response relationship of Xingnaojing injection in the treatment of traumatic brain coma in Beagle dogs

To observe the effect of Xingnaojing injection on the dose-response relationship of Beagle dog coma...

2022-03-21