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【Animal Modeling】-Animal Model of Spontaneous Disease

【Animal Modeling】-Animal Model of Spontaneous Disease

Spontaneous disease animal models, animal models that occur under natural conditions, or animal models that are preserved through genetic breeding without artificial treatment due to abnormal expression of gene mutations...

2021-01-07
Effect of ceramide on platelet-mediated blood transfusion-related acute lung injury in a mouse model

Effect of ceramide on platelet-mediated blood transfusion-related acute lung injury in a mouse model

To evaluate the mechanism of ceramide in aging platelets on blood transfusion-related acute lung injury...

2021-01-07
Selection guide for non-alcoholic fatty liver NASH mouse model

Selection guide for non-alcoholic fatty liver NASH mouse model

Nonalcoholic fatty liver disease (NAFLD, Nonalcoholic fatty liver disease) is a disease that stores too much fat in the liver...

2021-01-07
Neuroinflammatory response caused by brain injury in a rat model of lacunar cerebral infarction

Neuroinflammatory response caused by brain injury in a rat model of lacunar cerebral infarction

Sudden brain damage leads to the release of damage-related molecular patterns (DAMPs) and subsequent activation of local immune responses...

2021-01-07
New research looks at Xenopus biological activity

New research looks at Xenopus biological activity

In this study, researchers from Japan and Myanmar analyzed the phytochemical composition and biological characteristics of African spruce (Pirasma javanica) (also known as broadwood)...

2021-01-06
New model predicts that larger fish will suffer respiratory distress faster

New model predicts that larger fish will suffer respiratory distress faster

A new study conducted by Radboud University researchers in collaboration with international researchers from McGill University (Canada) and the University of Montana (USA) shows that large fishes suffer from respiratory distress more quickly in warm ...

2021-01-06
Research reveals the characteristics of SARS-CoV-2 infection in primates

Research reveals the characteristics of SARS-CoV-2 infection in primates

Scientists from Texas Biomed and Southwest National Primate Research Center (SNPRC) published their findings on a comprehensive animal model study of SARS-CoV-2 in the journal Nature Microbiology. These findings were originally published online on Bi...

2021-01-06
An improved jugular vein self-administering cannula for rats and its application

An improved jugular vein self-administering cannula for rats and its application

  Introduce an improved method for making jugular vein cannula and surgery method for jugular vein cannulation in rats, and apply it in an experimental study of autonomous drug administration in rats to evaluate the service life and application effec...

2021-01-06
The manufacture and application of the laser positioning instrument of the experimental animal magnetic resonance imaging system

The manufacture and application of the laser positioning instrument of the experimental animal magnetic resonance imaging system

Designed and developed a simple rat and mouse laser locator to provide a safe, convenient, accurate, inexpensive, and easy-to-operate experimental tool for medical nuclear magnetic resonance experiments...

2021-01-06
Study on the mechanism of jujube saponins alleviating Alzheimer\'s disease model mice

Study on the mechanism of jujube saponins alleviating Alzheimer's disease model mice

To explore the mechanism of Jujube saponins (ZSS) alleviating sevoflurane anesthesia in 9-month-old APP/PS1/tau three-transgenic Alzheimer\'s disease model mice...

2021-01-05
A comparative study of the effects of different factors on the establishment of a rat model of myocardial hypertrophy induced by isoproterenol

A comparative study of the effects of different factors on the establishment of a rat model of myocardial hypertrophy induced by isoproterenol

To observe and compare the effects of different genders and injection doses on the establishment of a rat model of myocardial hypertrophy induced by isoproterenol (ISO)...

2021-01-05
Establishment of lung metastasis and postoperative recurrence model in mice injected by bone marrow

Establishment of lung metastasis and postoperative recurrence model in mice injected by bone marrow

Establish models of lung metastasis and postoperative recurrence via bone marrow injection, reveal the superiority and feasibility of the model constructed by bone marrow injection, and provide a new research basis for studying lung metastasis of mal...

2021-01-05
Establishment of a rat model of coronary heart disease with combination of Qi deficiency and blood stasis syndrome

Establishment of a rat model of coronary heart disease with combination of Qi deficiency and blood stasis syndrome

Through the analysis of coronary heart disease syndrome of Qi deficiency and blood stasis syndrome combined with pathology, etiology, compound model tongue manifestations and the relationship with prostacyclin (PGI2) and thromboxane A2 (thromboxane A...

2021-01-05
Ovalbumin (OVA) sensitization combined with smoking method to establish a guinea pig model of cough variant asthma

Ovalbumin (OVA) sensitization combined with smoking method to establish a guinea pig model of cough variant asthma

Explore whether simple ligation of the left portal vein can form stable portal hypertension and whether nitric oxide plays a corresponding role in it...

2021-01-05
Establishment and applicability evaluation of animal model of pelvic organ prolapse

Establishment and applicability evaluation of animal model of pelvic organ prolapse

Establish a rat animal model that can reflect the similar pathological changes of the sacral ligament in patients with pelvic organ prolapse, and explore the influence of increasing the intensity of birth injury and simulating menopause on the pathol...

2021-01-05
Establishment and Characteristic Analysis of Inflammation Model of Fibroblast-like Synovial Cells in the Knee Joint of SD Rats Induced by Lipopolysaccharide

Establishment and Characteristic Analysis of Inflammation Model of Fibroblast-like Synovial Cells in the Knee Joint of SD Rats Induced by Lipopolysaccharide

Establish the primary culture method of normal knee joint synovial cells and lipopolysaccharide-induced fibroblast-like synovial cell inflammation model in rats...

2021-01-05