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Characteristics of cardiac structure and function pathology in a mouse model of pressure overload heart failure

Characteristics of cardiac structure and function pathology in a mouse model of pressure overload heart failure

Establish a mouse heart failure model, and use ultrasound imaging and pathological techniques to comprehensively evaluate the characteristic changes in cardiac function and structure during the development of the disease...

2021-01-05
Carbon tetrachloride induces inbred strain C57BL/6 mice to establish liver fibrosis model

Carbon tetrachloride induces inbred strain C57BL/6 mice to establish liver fibrosis model

Compare the effects of different doses of carbon tetrachloride on the inbred strain C57BL/6 mouse liver fibrosis model to establish a stable liver fibrosis model...

2021-01-05
Establishment and evaluation of rabbit knee osteoarthritis model

Establishment and evaluation of rabbit knee osteoarthritis model

Preparation and evaluation of rabbit knee osteoarthritis model by rabbit cartilage defect...

2021-01-05
Comparative study of bleomycin and endotoxin-induced pulmonary fibrosis in two strains of mice

Comparative study of bleomycin and endotoxin-induced pulmonary fibrosis in two strains of mice

By comparing the degree of pulmonary fibrosis induced by bleomycin and endotoxin in ICR and C57BL/6 strains of mice, a suitable mouse pulmonary fibrosis model can be established...

2021-01-05
Preparation and evaluation of MPTP-induced C57BL/6 mouse Parkinson model

Preparation and evaluation of MPTP-induced C57BL/6 mouse Parkinson model

Establish a stable 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced C57BL/6 mouse Parkinson model, and conduct behavioral evaluation of the model...

2021-01-05
Analysis of the preparation and comparison of animal models of facial paralysis

Analysis of the preparation and comparison of animal models of facial paralysis

Search the related literature of different models of facial paralysis animals, analyze the advantages and disadvantages of various model preparation methods, and explore the preparation methods suitable for different research types, so as to provide ...

2021-01-04
Preparation of a mouse model of chronic myocardial ischemia induced by different doses of isoproterenol and establishment of evaluation criteria

Preparation of a mouse model of chronic myocardial ischemia induced by different doses of isoproterenol and establishment of evaluation criteria

Different doses of isoproterenol (ISO) were injected subcutaneously into the neck to establish a model of chronic myocardial ischemia in mice, to determine the best model dose through comparison, to seek more objective and reliable indicators, and to...

2021-01-04
Experimental study of a mouse model of slow transit constipation induced by loperamide hydrochloride

Experimental study of a mouse model of slow transit constipation induced by loperamide hydrochloride

Through loperamide hydrochloride-induced slow transit constipation mouse model, compare the differences between the models induced by different doses and different administration times, and explore the establishment of a stable loperamide hydrochlori...

2021-01-04
Preparation method of long-term stable SD rat type 2 diabetes model

Preparation method of long-term stable SD rat type 2 diabetes model

Explore the preparation method of high-fat diet combined with streptozotocin-induced diabetes in rats, and provide a stable animal model of diabetes for clinical research...

2021-01-04
Long-term depression mouse model establishment and behavioral and neuropathological characteristics observation

Long-term depression mouse model establishment and behavioral and neuropathological characteristics observation

Construct a new type of long-term depression model mouse and compare the advantages of this type of mouse with common depression mouse models...

2021-01-04
Comparative study on establishing mouse models of allergic conjunctivitis under different conditions

Comparative study on establishing mouse models of allergic conjunctivitis under different conditions

  Establish allergic conjunctivitis mouse models under different antigens, different excitation pathways, and different ages of mice, and compare the immune response status to screen the best sensitization conditions, which is the establishment of al...

2021-01-04
The establishment of a new type of hyperlipidemia susceptible (WSHc) rat model of non-alcoholic fatty liver disease and the study of its pathological characteristics

The establishment of a new type of hyperlipidemia susceptible (WSHc) rat model of non-alcoholic fatty liver disease and the study of its pathological characteristics

Use a new type of hyperlipidemia susceptible rat to establish a non-alcoholic fatty liver disease model, observe the changes in blood biochemical indicators and pathological characteristics, explore its application and scientific research value, and ...

2021-01-04
Construction of a nude mouse model of clear cell renal carcinoma and study on the sensitivity of targeted drugs

Construction of a nude mouse model of clear cell renal carcinoma and study on the sensitivity of targeted drugs

Use patient-derived clear cell renal cancer cells to establish tumor animal models, detect the sensitivity of ccRCC PDCs to molecular targeted drugs, and provide theoretical and experimental basis for clinical diagnosis and treatment...

2021-01-04
The protective effect of anesthesia on the establishment of a rat model of severe trauma and hemorrhagic shock

The protective effect of anesthesia on the establishment of a rat model of severe trauma and hemorrhagic shock

Establish a modified rat model of severe trauma and hemorrhagic shock, and explore the protective effect of anesthesia on the establishment of STHS rat model...

2021-01-04
Evaluation and research progress of common behavior paradigms of mother-infant separation models

Evaluation and research progress of common behavior paradigms of mother-infant separation models

As an important way of early social deprivation, mother-infant separation has always been a classic animal model for studying the neurobiological mechanism of the adverse effects of early life stress on the individual\'s physiology and psychology....

2021-01-04
Two methods to construct a nude mouse orthotopic liver cancer model with spontaneous metastasis and easy to observe

Two methods to construct a nude mouse orthotopic liver cancer model with spontaneous metastasis and easy to observe

To construct a highly metastatic human hepatocellular carcinoma cell line labeled with Luc ̄GFP, two methods to establish an orthotopic liver cancer model in nude mice that is convenient for observation and spontaneously metastasized...

2020-12-30