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Current Status and Prospects of Research on Animal Models of Diseases in China

Current Status and Prospects of Research on Animal Models of Diseases in China

\"Science in China. Life Sciences\" published a review article entitled \"Research Status and Prospects of Animal Models of Diseases in China\" published by scholars from the Department of Medical Sciences of the National Natural ...

2020-12-21
New mouse model predicting liver cancer therapy

New mouse model predicting liver cancer therapy

Non-alcoholic fatty liver disease (Non Alcoholic Fatty Liver Disease, NAFLD) is a common disease that affects the health of about 30% of Americans. A large proportion of these people suffer from non-alcoholic fatty liver disease ( NASH), which often ...

2020-12-21
The first successful establishment of a mouse model of hereditary hypertension

The first successful establishment of a mouse model of hereditary hypertension

The research group of Professor Minsheng Zhu from the Institute of Model Animals of Nanjing University, Professor James T Stull from the Southwestern Medical Center and Professor Yang Xiao from the Academy of Military Sciences have discovered that th...

2020-12-21
Use mouse models to further clarify the relationship between inflammation and cancer

Use mouse models to further clarify the relationship between inflammation and cancer

A research team led by Dr. Nadia Carlesso, associate professor of pediatrics at Indiana University, found that, like a series of fallen dominoes, a series of molecular events in the bone marrow can produce high levels of inflammation, which can disru...

2020-12-21
A meta-analysis of the effects of anti-aging drugs on the survival curve of nematodes

A meta-analysis of the effects of anti-aging drugs on the survival curve of nematodes

A large number of studies at home and abroad have reported that anti-aging drugs can extend the lifespan of a variety of model organisms, including nematodes, fruit flies, mice, rats, and primates....

2020-12-21
Gene editing technology CRISPR promises to cure muscular dystrophy

Gene editing technology CRISPR promises to cure muscular dystrophy

Three research teams used CRISPR to cut out part of the defective gene in mice with Duchenne muscular dystrophy (DMD), allowing these rodents to make an essential muscle protein...

2020-12-21
Biochip capable of separating cancer cells in blood

Biochip capable of separating cancer cells in blood

The biochip developed by a research team at the University of New South Wales in Australia filters blood in a device called \"cancer dialysis\" to identify and remove cancer cells...

2020-12-21
MRI may replace lumbar puncture for the identification of neurodegenerative diseases

MRI may replace lumbar puncture for the identification of neurodegenerative diseases

Although the underlying neuropathology is different, Alzheimer\'s disease (AD) and frontotemporal lobe degeneration (FTLD) may have overlapping clinical manifestations, and the differential diagnosis is difficult, often requiring biopsy for pathologi...

2020-12-21
The effect of COVDI-19 on hyperglycemia

The effect of COVDI-19 on hyperglycemia

As COVID-19 is raging across the United States, researchers are studying how the virus can cause serious damage to the human body, especially for those who already have chronic diseases....

2020-12-18
Study on antitumor efficacy of recombinant human interferon endothelial inhibitor peptide fusion protein

Study on antitumor efficacy of recombinant human interferon endothelial inhibitor peptide fusion protein

Investigate the anti-tumor effect of the fusion protein I30 peptide and provide experimental support for the subsequent development of the I30 peptide...

2020-12-18
G protein-coupled estrogen receptor can reduce renal ischemia-reperfusion injury by inhibiting oxidative stress response

G protein-coupled estrogen receptor can reduce renal ischemia-reperfusion injury by inhibiting oxidative stress response

To investigate the effect of G protein-coupled estrogen receptor (GPER) on oxidative stress, and its protective effect on renal ischemia-reperfusion injury and possible mechanisms...

2020-12-18
Based on JAK2/STAT3/SOCS3 signal pathway to explore the effect of compound glycyrrhizin on experimental autoimmune encephalomyelitis

Based on JAK2/STAT3/SOCS3 signal pathway to explore the effect of compound glycyrrhizin on experimental autoimmune encephalomyelitis

To explore the preventive and therapeutic effects of compound glycyrrhizin (CG) on experimental autoimmune encephalomyelitis (EAE) mice and its influence on JAK2 / STAT3 / SOCS3 signal pathway...

2020-12-18
The host\'s unbalanced response to SARS-CoV-2 promotes the development of COVID-19

The host's unbalanced response to SARS-CoV-2 promotes the development of COVID-19

After the virus replicates, the physiological response to the virus infection usually begins at the cellular level. After the virus enters, the infected cells through any of the multiple pattern recognition receptors (PRR) will detect the replication...

2020-12-18
Effect of betulin on oxidative stress and apoptosis of PC12 cells induced by Aβ25-35

Effect of betulin on oxidative stress and apoptosis of PC12 cells induced by Aβ25-35

To investigate the effect of betulin on oxidative stress and apoptosis of PC12 cells induced by Aβ25-35...

2020-12-18
Astragalus Notoginseng Mixture Improves Renal Inflammation in Mice with Diabetic Nephropathy by Regulating Arid2-IR/NF-κB Signal Axis

Astragalus Notoginseng Mixture Improves Renal Inflammation in Mice with Diabetic Nephropathy by Regulating Arid2-IR/NF-κB Signal Axis

To study the therapeutic effect of Huangqi Sanqi Mixture on diabetic nephropathy (DN) mice and explore the underlying regulatory mechanism...

2020-12-18
Observation of the ultrastructure of Fufangjianerji against senile cochlear nerve cell apoptosis and up-regulating the expression of NeuN and BDNF

Observation of the ultrastructure of Fufangjianerji against senile cochlear nerve cell apoptosis and up-regulating the expression of NeuN and BDNF

Using transmission electron microscope to observe the effect of traditional Chinese medicine compound ear-invigorating agent on the apoptosis of outer hair cell (OHC) and spiral ganglion neurons (SGN) of senile cochlea in mice...

2020-12-18