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Effect of RNA interference inhibition of Beclin1 gene on proliferation and apoptosis of naked mole rat fibroblasts

Effect of RNA interference inhibition of Beclin1 gene on proliferation and apoptosis of naked mole rat fibroblasts

RNA interference technology was used to inhibit the expression of autophagy regulatory gene Beclin 1, and the effect of Beclin 1 expression on the proliferation and apoptosis of naked mole rat skin fibroblasts and the expression of p53, BAX, Bcl2 and...

2020-11-10
Effects of Suzi Oil on Insulin Sensitivity Related Gene Expression in Skeletal Muscle of Rats with Insulin Resistance

Effects of Suzi Oil on Insulin Sensitivity Related Gene Expression in Skeletal Muscle of Rats with Insulin Resistance

To explore the effects of a high-fat diet of Suzi oil rich in n-3 polyunsaturated fatty acid (PUFA) on insulin sensitivity and related gene expression in insulin-resistant rats...

2020-11-10
Lack of animal test data plagues biomedical research

Lack of animal test data plagues biomedical research

Two studies have revealed widespread flaws in animal test reports, and this is the latest result of a series of papers criticizing crude biomedical research...

2020-11-10
Solving the mystery of in vitro fertilization embryo defects in mouse experiments

Solving the mystery of in vitro fertilization embryo defects in mouse experiments

Having a child is the dream of many infertile couples. Thousands of children are born through in vitro fertilization (IVF). IVF means that the sperm and eggs of mammals complete the fertilization process in an artificially controlled environment outs...

2020-11-10
Alzheimer\'s disease drug causes brain cell damage in mice

Alzheimer's disease drug causes brain cell damage in mice

Can it also make Alzheimer\'s disease worse? Animal studies similar to the treatment of Alzheimer’s in humans have shown that the treated antibodies may actually be harmful...

2020-11-10
Study on the symptoms of spontaneous hindlimb paralysis in hyperlipidemia susceptible (WSHc) rats

Study on the symptoms of spontaneous hindlimb paralysis in hyperlipidemia susceptible (WSHc) rats

Observe the pathogenesis and pathological characteristics of rats with spontaneous hindlimb paralysis in the hyperlipidemia susceptible (WSHc) rat population, and preliminary study its pathogenesis, and explore its application and scientific research...

2020-11-09
A simple and convenient new method for extracting mouse cerebrospinal fluid

A simple and convenient new method for extracting mouse cerebrospinal fluid

Establish a simple and easy method for extracting mouse cerebrospinal fluid, low materials, high survival rate and success rate, and provide reference for related research on mouse cerebrospinal fluid...

2020-11-09
Role and mechanism of eNOS/NO pathway in renal interstitial microangiopathy in mice with unilateral ureteral obstruction

Role and mechanism of eNOS/NO pathway in renal interstitial microangiopathy in mice with unilateral ureteral obstruction

To investigate the effects of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) in the microvascular pathology of unilateral ureteral obstruction (UUO) renal interstitial fibrosis in mice And mechanism...

2020-11-06
The effect of endometriosis on the fertility of mice

The effect of endometriosis on the fertility of mice

Establish a mouse model of endometriosis and observe the effect of endometriosis on the pregnancy ability of the model mice...

2020-11-06
Animal experiment: Protective effect of Danggui Buxue Decoction on radiation-damaged mice

Animal experiment: Protective effect of Danggui Buxue Decoction on radiation-damaged mice

Observe the protective effect of Danggui Buxue Decoction on mice irradiated by 60C0-γ rays...

2020-11-06
Alzheimer\'s disease drug causes brain cell damage in mice

Alzheimer's disease drug causes brain cell damage in mice

Can it also make Alzheimer\\\'s disease worse? Animal studies similar to the treatment of Alzheimer’s in humans have shown that the treated antibodies may actually be harmful...

2020-11-06
Study on the effect of vaccine targeting RBP-4 on blood glucose reduction in type 2 diabetic mice

Study on the effect of vaccine targeting RBP-4 on blood glucose reduction in type 2 diabetic mice

Explore the effectiveness and feasibility of vaccine immune intervention with human-derived RBP-4 as the target for insulin resistance, and provide basic research data for the advancement of new treatment methods for type 2 diabetes...

2020-11-06
The effect of insufficient blood volume of SD large mouse on the four test results of coagulation

The effect of insufficient blood volume of SD large mouse on the four test results of coagulation

Discuss the best anticoagulation ratio in rats, and analyze the influence of insufficient blood volume of the specimen on the four test results of coagulation...

2020-11-06
Animal experiment: the combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

Animal experiment: the combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

To explore the effect of combined action of estrogen and androgen on blood lipid level and coagulation function in hyperlipidemia mice...

2020-11-06
Mouse brain plasticity promises to treat blindness

Mouse brain plasticity promises to treat blindness

The early brain is plastic, that is, the brain circuits are easily reorganized to promote learning. However, the brain loses most of its plasticity in adulthood, and it cannot quickly recover the lost functions after suffering an injury, such as a st...

2020-11-06
Comparison of four test results of blood coagulation in SD rats with two different reagents

Comparison of four test results of blood coagulation in SD rats with two different reagents

  Compare the test results of the four blood coagulation tests (PT, APTT, TT, FIB) of experimental animal SD rats and human blood coagulation reagents of two different brands of imported and domestic manufacturers, and observe whether there are diffe...

2020-11-06