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[Animal modeling] - Establishment of rat model of superior mesenteric vein thrombosis

[Animal modeling] - Establishment of rat model of superior mesenteric vein thrombosis

To establish a rat model of superior mesenteric vein thrombosis (SMVT) by ligation and simulate the pathological process of the disease, so as to provide basic preparation for the study of its pathogenesis and treatment...

2022-11-11
【Animal Modeling】-Changes of Blood Indexes in Long-term Toxicity Experiment of Niaotongkake Naiqi Tablets in Rats

【Animal Modeling】-Changes of Blood Indexes in Long-term Toxicity Experiment of Niaotongkake Naiqi Tablets in Rats

To investigate the changes of hematological indexes in the long-term toxicity test of Niaotongkake Naiqi tablets in rats...

2022-11-11
【Animal modeling】-The improvement effect of Xueshuantong capsule on tight junction injury of HUVEC cells induced by oxygen-glucose deprivation/reoxygenation

【Animal modeling】-The improvement effect of Xueshuantong capsule on tight junction injury of HUVEC cells induced by oxygen-glucose deprivation/reoxygenation

To investigate the protective effects of Panax notoginseng saponins (PNS) and its monomers Rg1-Rb1 on the damage of vascular endothelial tight junctions induced by oxygen-glucose deprivation (OGD) in a model of HUVEC cells induced by oxygen-glucose d...

2022-11-11
【Animal modeling】-Changes and significance of protein expression of microRNA-97a and TGF-β1 in myocardial tissue of spontaneously hypertensive rats

【Animal modeling】-Changes and significance of protein expression of microRNA-97a and TGF-β1 in myocardial tissue of spontaneously hypertensive rats

To observe the expression changes and relationship between Micro RNA-97a and TGF-β1 protein in myocardial tissue of spontaneously hypertensive rats (SHR)...

2022-11-11
【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

To screen out the single nucleotide polymorphisms that can rapidly identify four commonly used rat strains [Wistar rat, Goto-Kakizaki rat, Brown-Norway (BN) rat, Sprague-Dawley (SD) rat] sex locus and verify its reliability...

2022-11-11
[Animal modeling] - Changes of monoamine neurotransmitter content and neurofactor expression in brain region of rats with anxiety and depression

[Animal modeling] - Changes of monoamine neurotransmitter content and neurofactor expression in brain region of rats with anxiety and depression

To study the changes of monoamine neurotransmitters in hippocampus, amygdala and prefrontal cortex and the expression trend of neurotrophic factors in brain of anxiety depression model rats, and to explore its possible pathogenesis...

2022-11-11
【Animal Modeling】- Mouse spleen mesenchymal stem cells regulate the proliferation and activation of T lymphocytes

【Animal Modeling】- Mouse spleen mesenchymal stem cells regulate the proliferation and activation of T lymphocytes

To study the regulatory effect of mouse spleen mesenchymal stem cells (Sp-MSCs) on the proliferation and activation of T lymphocytes...

2022-11-10
【Animal Modeling】-Buulfan on the Injury of Hematopoietic Stem Cell Function in Mice

【Animal Modeling】-Buulfan on the Injury of Hematopoietic Stem Cell Function in Mice

To examine the effects of different administration methods on the function of hematopoietic stem cells in mice...

2022-11-10
【Animal Modeling】-Study on Intestinal Morphology and Energy Demand of Long-clawed Gerbils

【Animal Modeling】-Study on Intestinal Morphology and Energy Demand of Long-clawed Gerbils

To analyze the relationship between species differences and intestinal morphology and energy metabolism, and to clarify the energy requirements of gerbils...

2022-11-10
[Animal modeling] - Comparison of subcutaneous transplanted tumor models in different parts of Lewis lung cancer in mice

[Animal modeling] - Comparison of subcutaneous transplanted tumor models in different parts of Lewis lung cancer in mice

To explore the differences of subcutaneous transplantation of lung cancer in different parts of the body, and to provide a basis for lung cancer researchers...

2022-11-10
[Animal modeling] - Establishment of tree shrew model of Fusarium solani keratitis

[Animal modeling] - Establishment of tree shrew model of Fusarium solani keratitis

To establish a tree shrew model of Fusarium solanacearum keratitis by infecting the cornea of tree shrews with clinically isolated Fusarium solanacearum...

2022-11-10
【Animal Modeling】-The role of cAMP/CREB/BDNF signaling pathway in vortioxetine against depression-like behavior in mice

【Animal Modeling】-The role of cAMP/CREB/BDNF signaling pathway in vortioxetine against depression-like behavior in mice

To study the effect of vortioxetine, a novel antidepressant, on cyclic adenosine monophosphate/cyclic adenosine monophosphate response element binding protein/brain-derived neurotrophic factor (cAMP/CREB/BDNF) signal transduction pathway...

2022-11-10
[Animal modeling] - Plasma metabonomics study on the model of type 2 diabetes rats with abnormal black gallbladder syndrome

[Animal modeling] - Plasma metabonomics study on the model of type 2 diabetes rats with abnormal black gallbladder syndrome

To establish and analyze the characteristics of plasma metabonomics in type 2 diabetes (T2DM) rats with Uygur medicine abnormal black gallbladder syndrome...

2022-11-10
[Animal modeling] - Establishment and evaluation of rheumatoid arthritis combined with hypertension disease model

[Animal modeling] - Establishment and evaluation of rheumatoid arthritis combined with hypertension disease model

To establish a rat model of rheumatoid arthritis combined with hypertension, and to evaluate the characteristics of this model...

2022-11-10
[Animal modeling] - Establishment of animal model of dysuricemia type hyperuricemia

[Animal modeling] - Establishment of animal model of dysuricemia type hyperuricemia

To explore a reliable method to establish a rat model of dysuricemia, and lay a foundation for the study of the pathogenesis of dysuricemia and the optimization of the treatment plan...

2022-11-10
[Animal modeling] - Construction and preliminary application of xenotransplantation model of human liver cancer

[Animal modeling] - Construction and preliminary application of xenotransplantation model of human liver cancer

To establish a xenotransplantation model of human hepatocellular carcinoma (HCC) and explore its role in precision medical treatment of HCC...

2022-11-10