[Animal modeling] Detection of salsolinol N-methyltransferase activity in 6-hydroxydopa model rats

To establish a rat model of Parkinson\'s disease (PD) with 6-hydroxydopamine (6-OHDA) and determine the activity of salsolinol N-methyltransferase (SNMT) in peripheral blood lymphocytes of rats...

2022-11-04

[Animal modeling] - Establishment and evaluation of rabbit model of premature ovarian failure induced by cyclophosphamide

To compare the methods of establishing animal models of premature ovarian failure (POF) induced by cyclophosphamide (CPF) in rabbits under different injection methods, and to find the best way of modeling, so as to provide more suitable experimental ...

2022-11-04

[Animal modeling] - Establishment of chronic renal insufficiency model in mice induced by repeated injection of cisplatin

To establish a C57BL/6 mouse model of chronic kidney disease, explore the changes of tubule injury index and interstitial fibrosis degree with cisplatin modeling dose, and provide animal experimental basis for studying the progress from AKI to CKD...

2022-11-04

[Animal modeling] - Systematic evaluation of animal models of inflammation caused by fine atmospheric particles

To explore the pathogenic mechanism of air pollution on animals, and to establish an animal model of inflammation caused by air pollution by noninvasive tracheal instillation of PM2.5 suspension in BALB/c mice?...

2022-11-04

[Animal modeling] - Establishment of muscle atrophy model of cynomolgus monkey

To establish an animal model of muscle atrophy in cynomolgus monkeys by restricting lower limb activities, and to establish a method for model evaluation?...

2022-11-04

[Animal modeling] - Establishment of rat model of transplanted uterine leiomyoma tissue

By means of tissue transplantation in immunosuppressive rats, to establish a rat model of transplanted uterine leiomyoma, and to provide a new animal model for the study of uterine leiomyoma?...

2022-11-04

[Animal modeling] - Establishment of rat lumbar ventral nerve root traction model

In order to study the pathogenesis of amyotrophic lateral sclerosis and drug development, the rat model of ventral nerve root traction of the fourth lumbar spine was established, and the validity of the model was verified with brain-derived neurotrop...

2022-11-04

[Animal modeling] - Experimental study on the rat model of hypertension combined with hyperlipidemia

To establish a model of spontaneously hypertensive rats (SHR) with hyperlipidemia by feeding them with high-fat diet, and to evaluate their heart and kidney injuries, so as to provide pharmacodynamic animal models and relevant methods for the evaluat...

2022-11-04

[Animal modeling] - Exploration of establishing tree shrew model with chronic gastrointestinal mucosal injury

To explore the feasibility of establishing an animal model of chronic gastrointestinal mucosal injury in tree shrews...

2022-11-04

[Animal modeling] Establishment of cough variant asthma model in Brown Norway rats

To establish a simple and practical animal model of cough variant asthma in Brown\'s Norway (BN) rats sensitized with ovalbumin (OVA)...

2022-11-04

[Animal modeling] Construction of lung metastasis model of melanoma in c57bl/6j mice

To explore the factors influencing the establishment of C57BL/6J mouse melanoma lung metastasis model, including the tumor inoculation method, the number of cells inoculated and the tumor forming cycle...

2022-11-04

[Animal modeling] - Urine metabolomic study on the rat model of abnormal black bile syndrome in Uygur medicine

To evaluate and discuss the biological markers of the rat model of abnormal black bile syndrome in Uyghur medicine by combining the observation of external characteristics with the study of urine metabolome...

2022-11-04

[Animal modeling] Establishment and mechanism of BALB/c mouse model of total hysterectomy

To establish an experimental animal model of total hysterectomy in BALB/c mice, and to explore and analyze the characteristics and formation mechanism of the model...

2022-11-04

[Animal modeling] - Study on coagulation function of rat sepsis model

To investigate the changes of coagulation function in sepsis rat model induced by cecal ligation and puncture...

2022-11-04

[Animal modeling] - Comparison of pathological characteristics of collagen induced rheumatoid arthritis models in Wistar and Lewis rats

To investigate the differences of symptoms and pathological characteristics between Wistar and Lewis rat models of rheumatoid arthritis (RA) induced by bovine type II collagen (CII)...

2022-11-04

[Animal modeling] - Establishment of rat gastritis cancer transformation model and exploration of early diagnosis methods

To construct a rat model of gastritis and cancer transformation and explore new early serodiagnostic indicators of gastric cancer...

2022-11-03