[Animal modeling] - Animal experimental study on two different types of left atrial appendage occluders

To evaluate the feasibility and safety of left atrial appendage (LAA) closure with single disc cylindrical occluder and double disc split occluder...

2022-10-19

[Animal modeling] - Study on the protective effect and mechanism of estrogen on oxidative stress injury of mouse osteoblast MC3T3-E1

To investigate the protective effect and mechanism of estrogen on oxidative stress injury of mouse osteoblast MC3T3-E1...

2022-10-19

[Animal modeling] - Lipid lowering effect of citrus polymethoxy flavone biscuit on hyperlipidemia mice

This study is the first to evaluate the lipid-lowering effect of adding citrus polymethoxyflavone powder to biscuits in hyperlipidemia mouse model through the measurement of lipid metabolism experimental indicators, in order to provide a basis for de...

2022-10-19

【Animal modeling】-Optimization of dose-response relationship between N-ethyl-N-nitrosourea and cyclophosphamide in pig-a gene mutation test in rats

To study the effect of different doses of N-ethyl-N-nitrosourea (ENU) and cyclophosphamide (CP) on the deletion rate of ankyrin CD59 in peripheral blood red blood cells of SD rats, and to optimize the Pig-a gene mutation test Detection method...

2022-10-19

【Animal modeling】-Inhibitory effect of atrial natriuretic peptide on the growth of transplanted melanoma in knockout mice

To investigate the effect of atrial natriuretic peptide on the growth of melanoma...

2022-10-19

[Animal modeling] Effect of deletion of ubiquitin carboxyl terminal hydrolase 1 gene on reproductive system development of female mice

To study the effect of ubiquitin carboxyl terminal hydrolase L1 gene deletion on the reproductive system of female mice...

2022-10-18

[Animal modeling] - Animal experimental evaluation on the safety pharmacology of Tanreqing injection

To observe the effects of Tanreqing injection on cardiovascular system, respiratory system of Beagle dogs and central nervous system of ICR mice, and to provide experimental data for its safety in clinical use...

2022-10-18

[Animal modeling] - Study on the promoting effect and mechanism of cord blood mononuclear cells on angiogenesis in rats with acute myocardial infarction

To investigate the effect and mechanism of cord blood mononuclear cells (HCMNCs) on angiogenesis in rats with acute myocardial infarction (AMI)...

2022-10-18

[animal modeling] - systematic evaluation of the effect of placental differentially expressed proteins on the growth and development of placenta in rat model of gestational diabetes

to systematically evaluate the effects of placenta differentially expressed proteins on the growth and development of placenta in diabetes of pregnancy (GDM) rat model...

2022-10-18

[Animal modeling] - Effect of electroacupuncture on synaptic plasticity and microglial cell polarization in rats with cerebral ischemia

To investigate the effects of electroacupuncture on synaptic plasticity and microglial polarization in rats with focal cerebral ischemia, and to detect the expression of miR-21/signal transducer and activator of transcription 3 (STAT3) pathway...

2022-10-18

[Animal modeling] - Based on the rat OVX model, study the effect of estrogen deficiency on the degeneration of endplate chondrocytes

To investigate the effect of estrogen deficiency on the degeneration of endplate chondrocytes...

2022-10-18

[Animal modeling] - Improvement and evaluation of conditions of rat model of myocardial hypertrophy induced by isoproterenol based on implantable osmotic pump

Myocardial hypertrophy is an effective compensatory function with slow development, an adaptive response to hemodynamics or myocardial injury, and an independent risk factor leading to heart failure...

2022-10-18

[Animal modeling] - The effect of compound rehmannia granules on the regulation of serum cyclic nucleotides and the repair of dopaminergic neurons in Parkinson's disease mice with yin deficiency and

To explore the effect of Fufang Dihuang Granules on the regulation of serum cyclic nucleotides (cAMP, cGMP) and the repair of dopaminergic neurons in Parkinson\'s disease mice with yin deficiency and movement wind syndrome...

2022-10-18

【Animal Modeling】-Analysis of Right Heart Function in Rats with Alkaline Pulmonary Hypertension

To study the relationship between the evolution of pulmonary artery pressure and the evolution of right ventricular function...

2022-10-17

【Animal Modeling】-Discussion on Influencing Factors of Non-Human Primate Evaluation of Learning and Memory Function

The delayed response test based on the Wisconsin Universal Tester is a common method to evaluate the learning and memory ability of non-human primates. The experiment is affected by many factors during the process. The learning and memory ability has...

2022-10-17

【Animal Modeling】-Buulfan on the Injury of Hematopoietic Stem Cell Function in Mice

To examine the effects of different administration methods on the function of hematopoietic stem cells in mice...

2022-10-17