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【Animal Modeling】-Model of gastric ulcer caused by pyloric ligation

【Animal Modeling】-Model of gastric ulcer caused by pyloric ligation

After the pylorus is ligated, the gastric juice remains in the stomach, and the effects of gastric acid and pepsin are enhanced. The stomach enlarges the antrum due to the pylorus ligation, and the reflex stimulates the secretion of gastrin, leading...

2022-10-11
【Animal Modeling】-Influence of inflammatory factor storm on immune response to infection in aged mice

【Animal Modeling】-Influence of inflammatory factor storm on immune response to infection in aged mice

After highly pathogenic avian influenza-infected mice, over-expressed inflammatory factors, known as inflammatory factor storm, were detected in the lungs....

2022-10-11
【Animal Modeling】- Histopathological study of skin healing in miniature pigs after deep second-degree burns

【Animal Modeling】- Histopathological study of skin healing in miniature pigs after deep second-degree burns

To establish a pig model of deep second-degree scald, and to observe the histopathological changes of skin repaired at different time points...

2022-10-11
【Animal modeling】-Biological characteristics of type 2 diabetes db/db mice

【Animal modeling】-Biological characteristics of type 2 diabetes db/db mice

To observe the biological characteristics of db/db mice, and to provide the basis for the experimental research and application of this strain of animals...

2022-10-11
【Animal modeling】-Inhibitory effect of resveratrol on blood hypercoagulability in rats and its relationship with the expression of NF-κB

【Animal modeling】-Inhibitory effect of resveratrol on blood hypercoagulability in rats and its relationship with the expression of NF-κB

To study the effect of resveratrol on the formation of hypercoagulable state in rats and its relationship with the expression of NF-κB...

2022-10-11
【Animal modeling】-Application of reduced glutathione in biological purification and rapid reproduction of AG129 mice

【Animal modeling】-Application of reduced glutathione in biological purification and rapid reproduction of AG129 mice

AG129 mice are difficult to give birth naturally, and conventional in vitro fertilization reagents cannot be used to obtain enough embryos for transplantation...

2022-10-11
【Animal modeling】-Effect of Helicobacter hepatica infection on dextran sulfate sodium-induced chronic colitis model in mice

【Animal modeling】-Effect of Helicobacter hepatica infection on dextran sulfate sodium-induced chronic colitis model in mice

To investigate the effect of Helicobacter hepatica infection on chronic colitis induced by sodium dextran sulfate in mice...

2022-10-11
【Animal Modeling】-Preparation and Breeding of FAH Gene Knockout Cloned Miniature Pigs

【Animal Modeling】-Preparation and Breeding of FAH Gene Knockout Cloned Miniature Pigs

The shortage of donors is the main problem faced by organ transplantation, and the preparation of humanized organs is one of the effective ways to solve this problem...

2022-10-11
【Animal modeling】-The neuroprotective effect of erythropoietin in a rat model of hypoxic-ischemic encephalopathy

【Animal modeling】-The neuroprotective effect of erythropoietin in a rat model of hypoxic-ischemic encephalopathy

To make a hypoxic-ischemic encephalopathy model in neonatal rats, to study the cerebral protective effect of recombinant human erythropoietin (EPO) and the changes of HIE intestinal flora diversity in neonatal rats, for clinical application of EPO in...

2022-10-10
【Animal Modeling】-Oriented breeding and identification of Mfge8 knockout homozygous mice and their correlation with autoimmune diseases

【Animal Modeling】-Oriented breeding and identification of Mfge8 knockout homozygous mice and their correlation with autoimmune diseases

To breed and identify Mfge8 knockout C57BL/6 mice, obtain homozygous (Mfge8-/-) mice, and compare the serological and histological changes of Mfge8-/- mice...

2022-10-10
【Animal Modeling】-Study on the correlation between SLC1A2 gene SNP locus and the activity of Labrador retrievers and golden retrievers

【Animal Modeling】-Study on the correlation between SLC1A2 gene SNP locus and the activity of Labrador retrievers and golden retrievers

To detect the correlation between the SNP locus of SLCIA2 gene and the activity of Labrador retrievers and golden retrievers, in order to screen effective genetic molecular markers for the early selection and breeding of guide dogs...

2022-10-10
【Animal Modeling】-Zucker Diabetic Obesity Rats Cerebrovascular Disease Characteristics and Pathogenesis Study

【Animal Modeling】-Zucker Diabetic Obesity Rats Cerebrovascular Disease Characteristics and Pathogenesis Study

To observe the pathological characteristics of cerebrovascular disease in Zucker diabetic obese (ZDF) rats, and to preliminarily explore its pathogenesis, so as to provide experimental basis and theoretical basis for the application of ZDF rats...

2022-10-10
【Animal modeling】-Effect of knockout TRPC6 on MPTP-induced neuroinflammatory injury in mice

【Animal modeling】-Effect of knockout TRPC6 on MPTP-induced neuroinflammatory injury in mice

To detect the expression of TRPC6 channel in microglia in a mouse MPTP-induced neuroinflammation model, and to explore the effect of TRPC6 channel on inflammatory expression and dopaminergic neuron damage...

2022-10-10
【Animal Modeling】-Effect of high-fat diet on insulin resistance and expression of hepatic insulin receptor substrate 1 and 2 in Tibetan miniature pigs

【Animal Modeling】-Effect of high-fat diet on insulin resistance and expression of hepatic insulin receptor substrate 1 and 2 in Tibetan miniature pigs

To investigate the effect of high-fat diet on insulin resistance (IR) and the expression of hepatic insulin receptor substrate (IRS) 1 and 2 in Tibetan miniature pigs...

2022-10-10
【Animal modeling】-Analysis of the effect of portal hypertension on serum endotoxin and intestinal mucosa in rats

【Animal modeling】-Analysis of the effect of portal hypertension on serum endotoxin and intestinal mucosa in rats

To study the effect of simple portal hypertension on serum endotoxin and intestinal mucosa in rats?...

2022-10-10
【Animal Modeling】-Diagnosis of Spontaneous Diabetic Cynomolgus Monkeys and Changes in Bone Microstructure

【Animal Modeling】-Diagnosis of Spontaneous Diabetic Cynomolgus Monkeys and Changes in Bone Microstructure

To diagnose spontaneously diabetic cynomolgus monkeys and analyze the changes of their bone microstructure, in order to establish an animal model of spontaneous diabetes mellitus complicated with osteoporosis...

2022-10-10