[Animal modeling] - Overexpression of LAMP2A in substantia nigra improves motor function of Parkinson's disease rhesus monkey model

To observe the effect of over expression of lysosome associated membrane protein 2A in substantia nigra on motor behavior of experimental monkeys induced by chaperone mediated autophagy in a Parkinson\'s disease rhesus monkey model...

2022-10-19

[Animal modeling] - Construction and evaluation of humanized mouse model of pancreatic cancer immune system

To construct and evaluate a humanized mouse model of pancreatic cancer immune system in order to provide an ideal preclinical model for immunotherapy of pancreatic cancer...

2022-10-19

[Animal modeling] - Establishment of diffuse cerebral thrombosis model in rats induced by arachidonic acid

To establish and optimize the model of diffuse cerebral thrombosis induced by arachidonic acid in rats...

2022-10-19

[Animal modeling] Preparation of a mouse model of diarrhea predominant irritable bowel syndrome induced by acetic acid combined with restraint stress

To establish a mouse model of diarrhea predominant irritable bowel syndrome (IBS) by rectal perfusion with 3% acetic acid combined with restraint stress, and evaluate the feasibility of the model...

2022-10-19

[Animal modeling] Comparative study on visceral hypersensitivity model induced by combined method

To observe the effect of visceral hypersensitivity model of irritable bowel syndrome established by maternal infant separation combined with mechanical stimulation and drug combined with chronic stress, and discuss the advantages and disadvantages of...

2022-10-19

[Animal modeling] - Comparative study on rat model of chronic skin ulcer

To establish a rat model of chronic skin ulcer by different methods, and evaluate the differences and characteristics of different models by comparing various indicators...

2022-10-19

[Animal modeling] - Establishment of transgenic humanized ACE2 nude mouse model

To establish a human derived ACE2 (hACE2) transgenic nude mouse model with BALB/c-Nude nude mice as the background...

2022-10-19

[Animal modeling] - Establishment of mouse model of intrauterine adhesions by cervical mechanical injury combined with lipopolysaccharide perfusion

To establish an animal model of intrauterine adhesions according to the characteristics of clinical injury by using mechanical injury combined with lipopolysaccharide perfusion in a minimally invasive manner, so as to provide support for the in-depth...

2022-10-19

[Animal modeling] - Study on the conditions of modeling Parkinson's disease in rats with protease inhibitor

To observe the effects of different doses of protease inhibitor on behavior and tyrosine hydroxylase α- To explore the best condition of chronic model of Parkinson\'s disease induced by PSI...

2022-10-19

[Animal modeling] - 3D reconstruction of lungs and 3D printing model of vessels in miniature pigs

To explore the method of 3D reconstruction model of miniature pig lung and the application of 3D printing model...

2022-10-19

[Animal modeling] - Construction and evaluation of a mouse model of chronic cardiac toxicity induced by doxorubicin

To evaluate the effects of doxorubicin in different concentrations on cardiac toxicity in mice based on pathological changes...

2022-10-19

[Animal modeling] - Overexpression of LAMP2A in substantia nigra improves motor function of Parkinson's disease rhesus monkey model

To observe the effect of over expression of lysosome associated membrane protein 2A in substantia nigra on motor behavior of experimental monkeys induced by chaperone mediated autophagy in a Parkinson\'s disease rhesus monkey model...

2022-10-19

[Animal modeling] Establishment and evaluation of an animal model of Alzheimer's disease combined with phlegm and blood stasis

To explore and establish a reliable animal model of Alzheimer\'s disease combined with phlegm and blood stasis syndrome, and to provide the corresponding animal model for the prevention and treatment of AD by traditional Chinese medicine and provide ...

2022-10-19

[Animal modeling] - Changes of intestinal flora in atherosclerosis model of Wuzhishan miniature pigs induced by high-fat and high-sugar diet

To observe the changes of intestinal flora in atherosclerosis model of Wuzhishan mini pig induced by high-fat and high-sugar diet...

2022-10-19

[Animal modeling] Study on the effect of Siwu Mixture on primary dysmenorrhea model mice induced by oxytocin

To study the effect of Siwu mixture on primary dysmenorrhea in mice and its possible mechanism...

2022-10-19

[Animal modeling] - Child abusive brain injury animal model

Abusive head injury (AHT) is currently recognized as the name of intentional head injury to young children, because the head injury is not attributed to any specific pathogenesis. This neurological disease is also known as \"non accidental head ...

2022-10-19