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【Animal modeling】-Arachidonic acid-induced establishment of diffuse cerebral thrombosis model in rats

【Animal modeling】-Arachidonic acid-induced establishment of diffuse cerebral thrombosis model in rats

To establish and optimize the rat model of diffuse cerebral thrombosis induced by arachidonic acid...

2022-09-05
【Animal Modeling】-Comparative Study on Visceral Hypersensitivity Models Induced by Combined Method

【Animal Modeling】-Comparative Study on Visceral Hypersensitivity Models Induced by Combined Method

To observe the effect of maternal-infant separation combined with mechanical stimulation and drug combined with chronic stress on the visceral hypersensitivity model of irritable bowel syndrome, and to explore the advantages and disadvantages of the ...

2022-09-05
【Animal Modeling】-Comparative Study on the Rat Model of Chronic Skin Ulcer

【Animal Modeling】-Comparative Study on the Rat Model of Chronic Skin Ulcer

To construct a rat model of chronic skin ulcer by different methods, and to evaluate the differences and respective characteristics of different models through a variety of indicators...

2022-09-05
【Animal Modeling】-Israeli researchers create mouse embryo model with mouse stem cells

【Animal Modeling】-Israeli researchers create mouse embryo model with mouse stem cells

  In a new issue of the US journal Cell, Israeli researchers say they have used mouse stem cells to create a mouse embryonic model with an early brain and beating heart, a process that does not require sperm-egg fusion.   The researchers used mous...

2022-09-05
【Animal modeling】-Construction of mouse intrauterine adhesion model by transcervical mechanical injury combined with lipopolysaccharide perfusion

【Animal modeling】-Construction of mouse intrauterine adhesion model by transcervical mechanical injury combined with lipopolysaccharide perfusion

  Objective To construct an animal model of intrauterine adhesions that conforms to clinical injury characteristics by a minimally invasive method using mechanical injury combined with lipopolysaccharide perfusion, so as to provide support for in-dep...

2022-09-05
【Animal modeling】-Protease inhibitor on the conditions of rat Parkinson\'s disease modeling

【Animal modeling】-Protease inhibitor on the conditions of rat Parkinson's disease modeling

To observe the effects of different doses of protease inhibitors on rat behavior and the expression of tyrosine hydroxylase and α-synuclein in the substantia nigra, and to explore the optimal conditions for a chronic model of PSI-induced Parkinson\'s...

2022-09-05
【Animal modeling】-Construction and evaluation of doxorubicin-induced chronic cardiotoxicity model in mice

【Animal modeling】-Construction and evaluation of doxorubicin-induced chronic cardiotoxicity model in mice

To evaluate the modeling effect of different concentrations of doxorubicin-induced cardiotoxicity model in mice based on pathological changes...

2022-09-05
【Animal Modeling】- Overexpression of LAMP2A in the substantia nigra improves motor function in a rhesus monkey model of Parkinson\'s disease

【Animal Modeling】- Overexpression of LAMP2A in the substantia nigra improves motor function in a rhesus monkey model of Parkinson's disease

To observe the effect of substantia nigra overexpressing lysosome-associated membrane protein 2A up-regulating molecular chaperone-mediated autophagy on the motor behavior of experimental monkeys in a rhesus monkey model of Parkinson\'s disease...

2022-09-05
【Animal Modeling】-Establishment and evaluation of an animal model of Alzheimer\'s disease-phlegm-stasis syndrome combination

【Animal Modeling】-Establishment and evaluation of an animal model of Alzheimer's disease-phlegm-stasis syndrome combination

The purpose of this study is to explore the establishment of a reliable disease-syndrome combination animal model of Alzheimer\'s disease and phlegm-stasis syndrome, to provide a corresponding animal model for the prevention and treatment of AD with ...

2022-09-05
【Animal Modeling】-High-fat and high-sugar diet-induced changes in intestinal flora in Wuzhishan miniature pig atherosclerosis model

【Animal Modeling】-High-fat and high-sugar diet-induced changes in intestinal flora in Wuzhishan miniature pig atherosclerosis model

To observe the changes of intestinal flora in Wuzhishan miniature pig atherosclerosis model induced by high-fat and high-sugar diet...

2022-09-05
【Animal Modeling】-Research progress on artificially assisted reproductive technology and genetic modification models of marmosets

【Animal Modeling】-Research progress on artificially assisted reproductive technology and genetic modification models of marmosets

The common cotton-eared marmoset is a small non-human primate experimental animal. It has the advantages of low feeding cost, high reproductive efficiency, and short sexual maturity. It is very suitable for assisted reproductive technology and geneti...

2022-09-02
【Animal Modeling】-Establishment of rat gastritis-carcinoma transformation model and exploration of early diagnosis methods

【Animal Modeling】-Establishment of rat gastritis-carcinoma transformation model and exploration of early diagnosis methods

To construct a rat model of gastritis-carcinoma transformation, and to explore new serological indicators for early gastric cancer...

2022-09-02
【Animal Modeling】-Establishment and mechanism of high-fat and high-salt diet-induced hypertension model in Bama miniature pigs

【Animal Modeling】-Establishment and mechanism of high-fat and high-salt diet-induced hypertension model in Bama miniature pigs

To establish a hypertensive model of Bama miniature pigs with a high-fat and high-salt diet, and to explore its possible pathogenesis...

2022-09-02
【Animal Modeling】-Experimental Study on Establishing a Mouse Model of Hyperuricemia Kidney Damage

【Animal Modeling】-Experimental Study on Establishing a Mouse Model of Hyperuricemia Kidney Damage

To establish a reasonable and stable mouse model of hyperuricemia nephropathy, and to provide a pathological model for screening and researching drugs for the treatment of hyperuricemia nephropathy...

2022-09-02
Early mouse embryonic stem cell models are more accurate

Early mouse embryonic stem cell models are more accurate

Scientists at the Hub Hubrecht Institute (KNAW) and Cambridge University (UK) have successfully produced complex embryo-like structures from mouse embryonic stem cells. These structures, called gastric colloids, allow the ovaries to grow for the firs...

2022-09-02
【Animal Modeling】-Effects of propofol on tumor lung metastasis and the expression of MTA1 and Wnt1 in tumor-bearing rats

【Animal Modeling】-Effects of propofol on tumor lung metastasis and the expression of MTA1 and Wnt1 in tumor-bearing rats

To investigate the effect of different doses of propofol on the expression of MTA1 and Wnt1 in rat MADB106 cells lung metastasis and tumor tissue...

2022-09-02