[Animal modeling] - Effect of Sishen Pill on the expression of TLR4 and NOD2 in colon tissue of rats with ulcerative colitis

To compare the changes of Toll-like receptor 4 (TLR4) and nucleotide-binding oligomeric domain protein 2 (NOD2) in the colon tissue of rats before and after treatment, and to explore the mechanism of Sishen pill in treating ulcerative colitis (UC) fr...

2023-02-08

[Animal modeling] - Resveratrol improvement α- Study on the effect of synaptophysin A53T transgenic mice on motor dysfunction and regulation of peripheral immunity

To study the effect of resveratrol on α- Effects of Synuclein A53T transgenic mice on motor dysfunction and peripheral immunity...

2023-02-08

[Animal modeling] - Study on the anti-colon cancer effect of five species of Ferula in Xinjiang based on cell and animal experiments

To study the effects of five kinds of ferula from Xinjiang and their different polar parts on the proliferation inhibition and apoptosis of human colon cancer HCT 116 cells in vitro, and to study the effects of five kinds of ferula from Xinjiang on c...

2023-01-29

[Animal modeling] - protective effect of miR-214 on postoperative neuronal damage in rats anesthetized with propofol

To explore the effect of cannabinol on monoamine neurotransmitters in the central nervous system in methamphetamine dependent rats, explain the therapeutic mechanism of CBD on METH dependence, and provide reference for the development of drug depende...

2023-01-29

[Animal modeling] - Kaixinsan injected A into bilateral hippocampal CA1 area β Study on the therapeutic effect and mechanism of AD rats induced by 1-42

To investigate the effect of Kaixinsan on the injection of A into bilateral hippocampal CA1 region β The therapeutic effect of 1-42 on AD rats, and its mechanism of action is preliminarily clarified...

2023-01-29

【Animal Modeling】-partial simple epilepsy model in rats

1. Model animals: male or female rats weighing 200-300 g: drugs: pentobarbital, FeCl3 solution, equipment: rat stereotaxic device....

2022-05-18

【Animal Modeling】-Establishment of rat brain contusion model and behavioral evaluation

The purpose of the experiment is to use SD rats as experimental animals, and use a self-made free fall injury device to further develop a standardized and reproducible traumatic brain injury (TBI) animal model and behavior evaluation system. Build de...

2022-02-19

What is the procedure for tumor formation in nude mice?

Tumor cells can be divided into benign and malignant cells; cancer cells are malignant and spread. Tumor cells include cancer cells, and their common feature is cells that are out of control at the genetic level and can proliferate indefinitely. Canc...

2022-02-04

【Animal Modeling】-Chimpanzee HBV Model

Since the establishment of the HBV surface antigen detection system in the 1960s, chimpanzees are the first animals that are sensitive to human HBV. Chimpanzees infected with intravenous hepatitis B virus isolated from the serum of patients with hepa...

2022-02-03

【Animal Experiment】-Establishment of Morphine Dependence Rat Model

Purpose 　　(1) Familiar with the method of establishing morphine-dependent rat model, and copy the morphine-dependent rat model. 　　 (2) Observe and score the withdrawal symptoms of morphine-dependent rats to determine whether a morphine-dependen...

2022-02-03

【Animal Modeling】-Making and behavioral evaluation of free-falling blow model of mouse brain injury

With the development of the transportation and construction industry, the emergence of accidents and natural disasters, the incidence of traumatic brain injury (TBI) is gradually increasing. Traumatic brain injury ranks first among the causes of deat...

2022-02-02

[Zhonghong Boyuan] Online Hao Li-0 yuan lottery, National Finance Lectures

0 yuan draw! Participants also have prizes! There is also an experimental plan worth 200,000 yuan + 2,000 yuan experimental coupon...

2020-12-15

New coronavirus live virus isolated from Qingdao cold chain food packaging

On the 17th, a follow-up investigation was recently conducted on the official website of the Chinese Center for Disease Control and Prevention. The investigation involved a new type of coronary pneumonia epidemic in Qingdao. Covid-19 was detected in ...

2020-10-22

【Animal modeling】-Establishment of animal model of sciatic nerve injury

In the field of neurobiology, the factors that affect the repair of peripheral nerves after peripheral nerve injury are attracting people\'s attention. Known evidence shows that the main factors involved in nerve regeneration after peripheral nerve i...

2020-07-25

【Animal model】-Establishment and evaluation of rat tibia bone cancer pain model

According to the latest research, about one-third of patients with advanced cancer will have bone metastases, making bone cancer pain the most common type of pain in cancer patients, seriously affecting their quality of life. With the development of ...

2020-07-25

[Animal experiment]-Improved SD rat cerebrospinal fluid puncture collection technology

Cerebrospinal fluid is a specimen often used in animal experimental research, and has irreplaceable research value in the research fields of brain injury mechanisms, biomarkers and drug therapy. However, the rat ventricles and subarachnoid space are ...

2020-07-25