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【Animal modeling】-The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

【Animal modeling】-The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

This study was the first to evaluate the lipid-lowering effect of adding citrus polymethoxyflavone powder to biscuits by measuring lipid metabolism experimental indicators in a hyperlipidemia mouse model, aiming to provide a new functional food for d...

2023-03-08
【Animal Modeling】-Effects of microinjection of K252a into the hippocampus on behavioral and depressive-like classic indicators in rats

【Animal Modeling】-Effects of microinjection of K252a into the hippocampus on behavioral and depressive-like classic indicators in rats

To investigate the effects of K252a on rat behavior and classic depression-like indicators by microinjection of K252a into the hippocampus, and to establish a new animal model of depression...

2023-03-08
【Animal Modeling】-Construction and identification of an immunohumanized mouse model of prostate cancer

【Animal Modeling】-Construction and identification of an immunohumanized mouse model of prostate cancer

To construct a mouse model of humanized immune system and transplant it into human prostate cancer cell lines, so as to be used for the research of prostate cancer immunotherapy drugs...

2023-03-08
【Animal modeling】-Study on differential expression of lysozyme 1 in hatched and dormant blastocysts before and after superovulation in mice

【Animal modeling】-Study on differential expression of lysozyme 1 in hatched and dormant blastocysts before and after superovulation in mice

To study the distribution and expression of lysozyme LYZ1 gene in hatched blastocysts and dormant embryos of mice before and after superovulation, and to explore the new regulatory mechanism of animal embryo implantation...

2023-03-08
【Animal Modeling】-The effect of human umbilical cord mesenchymal stem cells on the level of autophagy in the hippocampus of natural aging rats

【Animal Modeling】-The effect of human umbilical cord mesenchymal stem cells on the level of autophagy in the hippocampus of natural aging rats

To investigate whether transplantation of human umbilical cord mesenchymal stem cells can improve learning and memory and cognitive decline by regulating the level of autophagy in naturally aging rats...

2023-03-08
【Animal Modeling】-Comparison of Ulcer Wound Healing in Two Type 2 Diabetic Mice

【Animal Modeling】-Comparison of Ulcer Wound Healing in Two Type 2 Diabetic Mice

To compare the ulcer wound healing characteristics of C57BL/6J-db/db and STZ-induced C57BL/6J mice with type 2 diabetes mellitus commonly used at present, and to conduct relevant animal experiments for the application of a stable diabetic mouse ulcer...

2023-03-07
【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

To explore the method of establishing 3D reconstruction model of minipig lung and the application of 3D printing model...

2023-03-07
[Animal modeling] - Effect of human umbilical cord mesenchymal stem cells on autophagy level in hippocampus of naturally aging rats

[Animal modeling] - Effect of human umbilical cord mesenchymal stem cells on autophagy level in hippocampus of naturally aging rats

To investigate whether transplantation of human umbilical cord mesenchymal stem cells can improve learning and memory and cognitive decline by regulating autophagy level in naturally aging rats...

2023-03-07
【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

To dynamically observe the pathological changes and characteristics of the liver of db/db mice with spontaneous type 2 diabetes mellitus, and to provide the basic theory and experimental basis for the experimental study of using the liver of db/db mi...

2023-03-04
【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

To screen out the single nucleosides that can rapidly identify four commonly used rat strains [Wistar rat, Goto-Kakizaki (GK) rat, Brown-Norway (BN) rat, Sprague-Dawley (SD) rat] Acid polymorphism (single nucleotide polymorphism, SNP) site and verify...

2023-03-04
【Animal modeling】-Comparative study on the induction of specific CD8+ T cell immune responses in C57BL/6 mice infected with influenza A virus H1N1pdm09 and PR8

【Animal modeling】-Comparative study on the induction of specific CD8+ T cell immune responses in C57BL/6 mice infected with influenza A virus H1N1pdm09 and PR8

To compare the two subtypes of influenza A virus H1N1 strains A/Shanghai/37T/2009(H1N1)(pdm09) clinical isolates and A/PuertoRico/8/34(H1N1)(PR8) standard strains infected with C57BL/6 small Changes in the pathological state and the induction of immu...

2023-03-04
【Animal Modeling】-Inflammatory model of body infected with Staphylococcus aureus

【Animal Modeling】-Inflammatory model of body infected with Staphylococcus aureus

To explore the body inflammatory response after deep second-degree burns in sterile rats infected with Staphylococcus aureus, and establish the post-burn and deep second-degree burns of sterile rats and SPF rats with Staphylococcus aureus...

2023-03-04
【Animal Modeling】-Effect of silencing heme oxygenase-1 on mouse model of acute monocytic leukemia

【Animal Modeling】-Effect of silencing heme oxygenase-1 on mouse model of acute monocytic leukemia

To investigate the effect of silencing the expression of heme oxygenase-1 on leukemia in a mouse model of acute monocytic leukemia...

2023-03-04
【Animal Modeling】-Expression of Perilipin in Kidney Tissue of Rats with Diabetic Nephropathy

【Animal Modeling】-Expression of Perilipin in Kidney Tissue of Rats with Diabetic Nephropathy

To observe the characteristics of rat diabetic nephropathy model and the diagnostic value of urinary LN for early DN, and to explore the expression of perilipin in the kidney of DN rats...

2023-03-04
【Animal Modeling】-Pathological Study of Spontaneous Hepatobiliary Hyperplasia in Aged Rats

【Animal Modeling】-Pathological Study of Spontaneous Hepatobiliary Hyperplasia in Aged Rats

To accumulate valuable research data on rat hepatic bile duct hyperplasia for related scientific research and new drug safety evaluation...

2023-03-04
【Animal Modeling】-The role of nerve growth factor antibody in mouse knee osteoarthritis pain model

【Animal Modeling】-The role of nerve growth factor antibody in mouse knee osteoarthritis pain model

Knee osteoarthritis (OA) is a common chronic degenerative disease characterized by degeneration of articular cartilage, synovitis, subchondral bone remodeling and joint muscle atrophy...

2023-03-04