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【Animal modeling】-Irbesartan can reduce the inflammatory response of myocardial tissue in type 2 diabetic db/db mice

【Animal modeling】-Irbesartan can reduce the inflammatory response of myocardial tissue in type 2 diabetic db/db mice

To investigate the protective effect of angiotensin Ⅱ receptor blocker (ARB) irbesartan on myocardial tissue inflammation in type 2 diabetic db/db mice and its cardioprotective mechanism...

2023-03-04
【Animal Modeling】-Analysis of fecal microbial diversity of wild tree shrews using Illumina MiSeq sequencing platform

【Animal Modeling】-Analysis of fecal microbial diversity of wild tree shrews using Illumina MiSeq sequencing platform

To analyze the structure and composition of the fecal flora of wild tree shrew by high-throughput sequencing technology, and to lay a foundation for the further development and utilization of this new experimental animal...

2023-03-04
【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

The osteoporosis model constructed by ovariectomized rats is the most suitable model for the study of postmenopausal osteoporosis...

2023-03-04
【Animal Modeling】-VEGF-A Inhibitor sFLT-1 Improves Renal Function in Type 1 Diabetic Mice

【Animal Modeling】-VEGF-A Inhibitor sFLT-1 Improves Renal Function in Type 1 Diabetic Mice

To investigate whether VEGF-A inhibitor sFLT-1 can reverse the renal damage in type 1 diabetic mice by inhibiting the activation and inflammatory response of vascular endothelial cells...

2023-03-04
[Animal modeling] - Characteristics of changes in articular cartilage and subchondral bone in different animal models of osteoarthritis

[Animal modeling] - Characteristics of changes in articular cartilage and subchondral bone in different animal models of osteoarthritis

To investigate the pathological changes of subchondral bone and articular cartilage in different animal models of osteoarthritis...

2023-03-04
【Animal Modeling】-Effect of Henggu Bone Injury Healing Agent on Blood Physiology and Organ Coefficients of Fractured Tree Shrews

【Animal Modeling】-Effect of Henggu Bone Injury Healing Agent on Blood Physiology and Organ Coefficients of Fractured Tree Shrews

To evaluate the effect of Henggu bone wound healing agent on blood physiological indexes and organ coefficients of castrated tree shrew osteoporotic fracture model...

2023-03-04
【Animal modeling】-The synergistic and detoxifying effect of pine pollen assisted by paclitaxel combined with platinum-based chemotherapy

【Animal modeling】-The synergistic and detoxifying effect of pine pollen assisted by paclitaxel combined with platinum-based chemotherapy

To study whether pine pollen has attenuating and synergistic effects on paclitaxel combined with platinum-based chemotherapy...

2023-03-03
【Animal modeling】-Sevoflurane on the proliferation of neural stem cells in neonatal rats

【Animal modeling】-Sevoflurane on the proliferation of neural stem cells in neonatal rats

To study the effect of sevoflurane on the proliferation of neural stem cells in neonatal rats...

2023-03-03
【Animal Modeling】-The effect of human umbilical cord mesenchymal stem cells on the level of autophagy in the hippocampus of natural aging rats

【Animal Modeling】-The effect of human umbilical cord mesenchymal stem cells on the level of autophagy in the hippocampus of natural aging rats

To investigate whether transplantation of human umbilical cord mesenchymal stem cells can improve learning and memory and cognitive decline by regulating the level of autophagy in naturally aging rats...

2023-03-03
【Animal Modeling】-Establishment of basic data of embryo-fetal developmental toxicity test in Bama miniature pigs

【Animal Modeling】-Establishment of basic data of embryo-fetal developmental toxicity test in Bama miniature pigs

To detect the reproductive function indicators and fetal developmental indicators of the embryo-fetal developmental toxicity test in Bama miniature pigs, and to provide reference data for the developmental toxicity study of Bama miniature pigs...

2023-03-03
【Animal modeling】-In vivo biological properties of the porous composite HAPw/n-ZnO implanted in the back muscles of tree shrew

【Animal modeling】-In vivo biological properties of the porous composite HAPw/n-ZnO implanted in the back muscles of tree shrew

To preliminarily investigate the in vivo biological properties of the porous composite HAPw/n-ZnO...

2023-03-03
【Animal Modeling】-Effects of different samples and methods on the determination of blood biochemical indexes in rats

【Animal Modeling】-Effects of different samples and methods on the determination of blood biochemical indexes in rats

To compare the effects of two different samples of serum and plasma and different test methods on the measured values of blood biochemical indexes and blood glucose in rats...

2023-03-03
【Animal Modeling】-High-throughput sequencing to study the effects of drinking water with different pH on the intestinal microbes of SPF mice

【Animal Modeling】-High-throughput sequencing to study the effects of drinking water with different pH on the intestinal microbes of SPF mice

To study the effects of drinking water with different pH on gut microbial diversity in SPF mice...

2023-03-02
【Animal Modeling】-Measurement and Significance of Noninvasive Pulmonary Function in Mice

【Animal Modeling】-Measurement and Significance of Noninvasive Pulmonary Function in Mice

To detect non-invasive pulmonary function indexes in C57BL/6 mice, and to provide a basis for the monitoring of pulmonary function in experimental studies in mice...

2023-03-02
【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

To investigate the effect of astragaloside Ⅱ on interleukin-21 ( IL-21 ) / signal transducer and activator of transcription 3 ( STAT3 ) pathway and airway inflammation in juvenile asthmatic rats...

2023-03-02
【Animal modeling】-Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in experimental autoimmune encephalomyelitis rats

【Animal modeling】-Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in experimental autoimmune encephalomyelitis rats

To investigate the effect of paclitaxel on the expression of CD28 and CTLA-4 in the brain tissue of rats with experimental autoimmune encephalomyelitis and the content of B cell stimulating factor (BAFF) in the supernatant of spleen tissue and its si...

2023-03-02