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【Animal modeling】-The dose-response relationship of Xingnaojing injection in the treatment of traumatic brain coma in Beagle dogs

【Animal modeling】-The dose-response relationship of Xingnaojing injection in the treatment of traumatic brain coma in Beagle dogs

To observe the effect of Xingnaojing injection on the dose-response relationship of Beagle dog coma...

2022-04-18
【Animal Modeling】-Xiamen University Efficiently Editing Plasmodium Genomes Using CRISPR/Cas9 System

【Animal Modeling】-Xiamen University Efficiently Editing Plasmodium Genomes Using CRISPR/Cas9 System

Using the CRISPR/Cas9 system, the research group of Professor Yuan Jing from the School of Life Sciences of Xiamen University has efficiently achieved different types of modifications of multiple genes in the Plasmodium genome, including gene deletio...

2022-04-18
【Animal Modeling】-Long non-coding RNA TUG1 regulates the mechanism of miR-137 involved in nerve injury in rats with focal cerebral ischemia

【Animal Modeling】-Long non-coding RNA TUG1 regulates the mechanism of miR-137 involved in nerve injury in rats with focal cerebral ischemia

To investigate the role of long non-coding RNA (LncRNA) taurine up-regulated gene 1 (TUG1) regulating microRNA (miR)-137 involved in nerve injury in rats with focal cerebral ischemia...

2022-04-18
【Animal Modeling】-Optimization of the freezing method of cynomolgus monkey semen without yolk freezing solution

【Animal Modeling】-Optimization of the freezing method of cynomolgus monkey semen without yolk freezing solution

Due to the existence of uncertain components such as yolk in traditional sperm freezing solutions, there is a risk of biological contamination. Therefore, this study aimed to use Origio and Quinn\'s two commercial yolk-free cryopreservations to prese...

2022-04-18
【Animal Modeling】-Tail-clamped somatosensory stimulation inhibits the excitability of pyramidal neurons in the hippocampal CA1 region of rats

【Animal Modeling】-Tail-clamped somatosensory stimulation inhibits the excitability of pyramidal neurons in the hippocampal CA1 region of rats

Dr. Feng Zhouyan\'s team from Zhejiang University, China used microelectrode arrays to monitor neuronal activity in the hippocampus of rats, and found that the sensory stimulation of tail clipping would induce different types of neurons to produce di...

2022-04-18
【Animal Modeling】-Umbilical cord blood mononuclear cells promote angiogenesis in rats with acute myocardial infarction and its mechanism

【Animal Modeling】-Umbilical cord blood mononuclear cells promote angiogenesis in rats with acute myocardial infarction and its mechanism

To investigate the effect and mechanism of cord blood mononuclear cells (HCMNCs) on angiogenesis in acute myocardial infarction (AMI) rats...

2022-04-16
【Animal Modeling】-Effects of hesperidin on antioxidant activity and gene expression of antioxidant enzymes in mice

【Animal Modeling】-Effects of hesperidin on antioxidant activity and gene expression of antioxidant enzymes in mice

To investigate the effect of hesperidin (HDN) on the antioxidant effect of the body...

2022-04-16
【Animal Modeling】-Effect of Simvastatin Combined with Risedronate on Bone Loss Induced by Tail Suspension in Mice

【Animal Modeling】-Effect of Simvastatin Combined with Risedronate on Bone Loss Induced by Tail Suspension in Mice

To investigate and compare the effects of simvastatin and risedronate sodium alone or in combination on dexamethasone-induced osteoporosis in mice...

2022-04-16
【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

To observe the effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats...

2022-04-16
【Animal Modeling】-Study on Oral Rehydration Salts Reducing Mortality in Rats with Lithium Chloride-Pilocarpine Status Convulsions

【Animal Modeling】-Study on Oral Rehydration Salts Reducing Mortality in Rats with Lithium Chloride-Pilocarpine Status Convulsions

To investigate a method for reducing mortality in a lithium chloride-pilocarpine-induced status convulsive model by gastric gavage with modified oral rehydration salts...

2022-04-16
【Animal modeling】-Construction and phenotype analysis of Fancm gene knockout mice

【Animal modeling】-Construction and phenotype analysis of Fancm gene knockout mice

To construct Fanconi anemia pathway Fancm gene knockout mice to study the effect of Fancm gene deletion on mouse physiological functions, especially male reproductive organs...

2022-04-16
【Animal Modeling】-Hemophilia Gene Therapy Animal Trials Successfully

【Animal Modeling】-Hemophilia Gene Therapy Animal Trials Successfully

Hemophilia is a disease caused by hereditary coagulation dysfunction, which is characterized by the inability of the body to produce coagulation factors or insufficient production of coagulation factors, resulting in prolonged coagulation time and di...

2022-04-15
【Animal Modeling】- Camouflage technology inspired by skin cells of cephalopods

【Animal Modeling】- Camouflage technology inspired by skin cells of cephalopods

A study found that combining a temperature-sensitive dye on a thin, flexible electrical substrate with a distributed light sensor could lead to systems that have the ability to automatically adapt to match the color of their surroundings, as a way fr...

2022-04-15
【Animal Modeling】-Genetic Screening of Mutants with Defective Digestive Organ Development in Zebrafish

【Animal Modeling】-Genetic Screening of Mutants with Defective Digestive Organ Development in Zebrafish

Forward Genetic Screening of Zebrafish Liver, Intestine and Gallbladder Development Defective Mutants...

2022-04-14
【Animal Modeling】-Establishment of real-time quantitative PCR method for mouse hepatitis virus and its application in some rodents

【Animal Modeling】-Establishment of real-time quantitative PCR method for mouse hepatitis virus and its application in some rodents

To establish a real-time quantitative PCR detection method for mouse hepatitis virus (MHV), and apply it to the detection of rodents such as nude-waisted mice...

2022-04-14
【Animal modeling】-Analysis of the localization and expression of vitamin D receptor in the duodenum of C57BL/6 mice

【Animal modeling】-Analysis of the localization and expression of vitamin D receptor in the duodenum of C57BL/6 mice

To investigate the localization and expression of vitamin D receptors in the duodenum of C57BL/6 mice, and to study the correlation between vitamin D system and intestinal development...

2022-04-13