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【Animal Modeling】-Isoproterenol-induced angina pectoris animal model

【Animal Modeling】-Isoproterenol-induced angina pectoris animal model

Isoproterenol is a catecholamine-based drug, which is a β-adrenergic receptor agonist, which can increase myocardial contraction and oxygen consumption, thereby increasing myocardial burden and myocardial microcirculation, and causing myocardial dama...

2022-04-22
[Animal modeling]-Myocardial regeneration occurs only on the first day after the mouse is born

[Animal modeling]-Myocardial regeneration occurs only on the first day after the mouse is born

Scientists claim to observe myocardial regeneration in newborn mice. Then they reported that after a piece of the small heart of the newborn mouse was cut, the heart muscle would regenerate. This is a self-repair....

2022-04-22
【Animal Modeling】-Miniature Pig Pulpitis Model

【Animal Modeling】-Miniature Pig Pulpitis Model

Experimental method There are 5 piglets weighing 14 to 26 kg in China, 3 males and 2 females. Select upper and lower first permanent molars and bilateral incisors to create a pulpitis model...

2022-04-22
【Animal modeling】-Effect of microcystin-LR on mitochondrial function of mouse primary hepatocytes

【Animal modeling】-Effect of microcystin-LR on mitochondrial function of mouse primary hepatocytes

Microcystin contamination caused by cyanobacterial blooms is one of the topics of concern worldwide. Microcystin LR (MC-LR) has strong specific hepatotoxicity, but the exact mechanism of its hepatic injury has not been fully elucidated...

2022-04-22
【Animal Modeling】-Analysis of single nucleotide polymorphisms and alternative splicing before and after freezing blastocysts of bovine cattle based on RNA-Seq technology

【Animal Modeling】-Analysis of single nucleotide polymorphisms and alternative splicing before and after freezing blastocysts of bovine cattle based on RNA-Seq technology

To compare and analyze the single nucleotide polymorphisms and alternative splicing of bovine blastocysts before and after vitrification...

2022-04-21
【Animal modeling】-Changes of C-reactive protein and inflammatory factors in Pterima pig model of plateau multiple organ dysfunction syndrome

【Animal modeling】-Changes of C-reactive protein and inflammatory factors in Pterima pig model of plateau multiple organ dysfunction syndrome

To study the changes of tumor necrosis factor-α, interleukin-1β and C-reactive protein in the process of inflammatory reaction in the Phenma pig model of plateau multiple organ dysfunction syndrome...

2022-04-21
【Animal Modeling】-Rat Lumbar Spinal Canal Stenosis Model

【Animal Modeling】-Rat Lumbar Spinal Canal Stenosis Model

Reproduction method Anesthetize rats by intraperitoneal injection of phenobarbital at 50 mg/kg body weight...

2022-04-20
【Animal Modeling】- Improvement and effect evaluation of tracheal instillation in rats

【Animal Modeling】- Improvement and effect evaluation of tracheal instillation in rats

To establish a non-invasive tracheal instillation method for rats with visual, simple, rapid and precise instillation...

2022-04-20
[Animal model]-What are the common fish experimental animal species?

[Animal model]-What are the common fish experimental animal species?

Since fish live in water for life, these materials are easy to obtain, most of which are in vitro fertilization and in vitro development, such as toxicity testing, environmental monitoring, developmental biology, physiology, ecology, genetics and oth...

2022-04-20
【Animal Modeling】-Atherosclerosis model of insulin resistance in white-haired black-eyed rabbits and Japanese big-eared white rabbits

【Animal Modeling】-Atherosclerosis model of insulin resistance in white-haired black-eyed rabbits and Japanese big-eared white rabbits

To investigate the phenotypic differences and pathological mechanisms of insulin resistance atherosclerosis models in white-haired black rabbits and Japanese big-eared white rabbits...

2022-04-20
【Animal Modeling】-Analysis of Factors Affecting the Production Efficiency of Bacterial Artificial Chromosome Transgenic Mice

【Animal Modeling】-Analysis of Factors Affecting the Production Efficiency of Bacterial Artificial Chromosome Transgenic Mice

To compare several key factors in the development of bacterial artificial chromosome transgenic mice, such as the genetic background of experimental mice, BAC plasmid injection concentration, BAC plasmid fragment size and BAC injection storage time,...

2022-04-20
【Animal modeling】-The role of CaN-NFATc3 pathway in restenosis after balloon dilation of abdominal aorta in rats

【Animal modeling】-The role of CaN-NFATc3 pathway in restenosis after balloon dilation of abdominal aorta in rats

To study the role of calcineurin (CaN) and its downstream activated T cell nuclear factor (NFATc3) in restenosis after balloon dilation, and to provide a new theoretical basis for the prevention and treatment of vascular restenosis...

2022-04-20
【Animal Modeling】-Comparison of the difference of glutamate-induced swelling of cultured astrocytes between two varieties of rats

【Animal Modeling】-Comparison of the difference of glutamate-induced swelling of cultured astrocytes between two varieties of rats

To compare the differences of glutamate-induced cell swelling by cultured astrocytes (AST) in Wistar rats and SD rats...

2022-04-20
【Animal Model】-Interventional effect of valsartan on the activity of rat glomerular mesangial cells induced by high glucose

【Animal Model】-Interventional effect of valsartan on the activity of rat glomerular mesangial cells induced by high glucose

To investigate the effect and mechanism of valsartan on the proliferation and apoptosis of rat renal cells induced by high glucose...

2022-04-18
【Animal modeling】-Comparative study on bone growth in rats after long-term exposure to low-fluoride aluminum and short-term high-fluoride aluminum exposure

【Animal modeling】-Comparative study on bone growth in rats after long-term exposure to low-fluoride aluminum and short-term high-fluoride aluminum exposure

To observe the effects of different doses of fluoride and aluminum combined with the duration of intake on longitudinal bone growth and bone metabolism in rats...

2022-04-18
【Animal Modeling】-Determination and Analysis of Hematology and Serum Biochemical Indexes in African Green Monkeys

【Animal Modeling】-Determination and Analysis of Hematology and Serum Biochemical Indexes in African Green Monkeys

To detect the hematology and serum biochemical indexes of 50 healthy African green monkeys, and to analyze the hematology and serum biochemistry of African green monkeys of different genders and age groups (young group: 1-3 years old, adult group: 4-...

2022-04-18