[Animal modeling] - Transcriptome analysis of colon tissue in IBD mice under the intervention of mesalazine

To detect the changes of gene expression in colon tissue of mice with inflammatory bowel disease (IBD) by transcriptome sequencing, and to improve the understanding of the molecular mechanism of mesalazine in the treatment of IBD...

2022-12-07

[Animal modeling] - Study on the effect and mechanism of Bushen Yiqi Huayu Granule on angiogenesis in ovariectomized osteoporosis model rats

Purpose based on TLRs/NF- κ B signal pathway was used to explore the effect of Bushen Yiqi Huayu Granule on angiogenesis in osteoporosis rats...

2022-12-07

[Animal modeling] - Pancreatic kallidinogenase alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

To investigate the effects of pancreatic kallidinogenase on myocardial injury, oxidative stress and fibrosis in rats with myocardial ischemia reperfusion injury...

2022-12-07

[Animal modeling] - The regulatory effect of curcumin and/or aerobic exercise on intestinal function in rats with dyslipidemia

to investigate the effects of curcumin and/or aerobic exercise on intestinal function in dyslipidemic rats...

2022-12-07

[Animal modeling] - Effect of compound microecological preparation on intestinal immune function of mice

To study the effect of compound microecological preparation on intestinal mucosal immune function in mice...

2022-12-06

[Animal modeling] - Protective effect of Dahuang Mudan decoction on liver injury in rats with acute pancreatitis

To investigate the protective effect of Dahuang Mudan decoction on liver injury in rats with acute pancreatitis...

2022-12-06

[Animal modeling] Study on the effect of Siwu Mixture on primary dysmenorrhea model mice induced by oxytocin

To study the effect of Siwu mixture on primary dysmenorrhea in mice and its possible mechanism...

2022-12-06

[Animal modeling] - Study on the influence and mechanism of different styles of music on the behavior of CUMS depression rats

To establish a depression model of SD rats by chronic mild unpredictable stimulation, and to explore the effects and mechanisms of different styles of music in improving depression like behavior in SD rats...

2022-12-06

[Animal modeling] - Based on autophagy, explore the effect of fentanyl combined with propofol on myocardial ischemia-reperfusion injury in rats

To investigate the effect of fentanyl combined with propofol on myocardial ischemia-reperfusion injury in rats based on autophagy...

2022-12-06

[Animal modeling] - Effect of atorvastatin on myelin repair and RhoA/Rock1 pathway in mice with autoimmune encephalomyelitis

To investigate the effects of atorvastatin on myelin repair and RhoA/Rock1 pathway in mice with autoimmune encephalomyelitis (EAE)...

2022-12-06

[Animal modeling] - The intervention effect of flavonoids in Sandiaojin on ulcerative colitis in mice and its effect on intestinal flora

To investigate the effects of total flavones of Sandiajin and its monomers, calycosin and sessile, on ulcerative colitis (UC) induced by dextran sodium sulfate (DSS) in mice and intestinal flora...

2022-12-06

[Animal modeling] - Study on the safety and effectiveness of human umbilical cord mesenchymal stem cells in the treatment of acute lung injury in mice

To investigate the safety and efficacy of human umbilical cord mesenchymal stem cells (HUC MSCs) in the treatment of lipopolysaccharide (LPS) - induced acute lung injury in mice...

2022-12-06

[Animal modeling] - Based on the rat OVX model, study the effect of estrogen deficiency on the degeneration of endplate chondrocytes

To investigate the effect of estrogen deficiency on the degeneration of endplate chondrocytes...

2022-12-06

[Animal modeling] - Improvement and evaluation of conditions of rat model of myocardial hypertrophy induced by isoproterenol based on implantable osmotic pump

Myocardial hypertrophy is an effective compensatory function with slow development, an adaptive response to hemodynamics or myocardial injury, and an independent risk factor leading to heart failure...

2022-12-06

[Animal modeling] - The effect of compound rehmannia granules on the regulation of serum cyclic nucleotides and the repair of dopaminergic neurons in Parkinson's disease mice with yin deficiency and

To investigate the effect of compound rehmannia granules on the regulation of serum cyclic nucleotides and the repair of dopamine neurons in Parkinson\'s disease mice with yin deficiency and wind movement syndrome...

2022-12-06

[Animal modeling] - Effect of arginine vasopressin 1b receptor knockout on anxiety and social behavior of female rats

to investigate the effects of arginine vasopressin 1b receptor gene knockout on plasma corticosterone content, anxiety and social behavior in female rats...

2022-12-06