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[Animal model] - Preparation and evaluation of rat model of acute myocardial injury induced by different doses of isoproterenol

[Animal model] - Preparation and evaluation of rat model of acute myocardial injury induced by different doses of isoproterenol

To study the effects of different doses of isoproterenol on cardiac function and pathomorphology in rats...

2022-10-31
[Animal modeling] - The role of GIPR signal transduction in adipose tissue of mouse model in insulin resistance and liver steatosis

[Animal modeling] - The role of GIPR signal transduction in adipose tissue of mouse model in insulin resistance and liver steatosis

To evaluate the role of GIP receptor (GIPR) signal transduction in insulin resistance and liver steatosis in mouse model adipose tissue by ultrasound...

2022-10-31
【Animal Modeling】-The synergistic effect of acupuncture on human amniotic mesenchymal cell transplantation in the treatment of osteoporosis in ovariectomized rats

【Animal Modeling】-The synergistic effect of acupuncture on human amniotic mesenchymal cell transplantation in the treatment of osteoporosis in ovariectomized rats

To investigate the synergistic effect of acupuncture combined with human amniotic mesenchymal cell transplantation on ovariectomized osteoporosis...

2022-10-26
【Animal modeling】-The effect of targeted inhibition of macrophage Act1 expression on ulcerative colitis

【Animal modeling】-The effect of targeted inhibition of macrophage Act1 expression on ulcerative colitis

To investigate the role of macrophage NF-κB activating factor 1 in inflammatory bowel disease...

2022-10-26
【Animal modeling】-Experimental study on puerarin alleviating radiation-induced acute intestinal mucosal injury in rats

【Animal modeling】-Experimental study on puerarin alleviating radiation-induced acute intestinal mucosal injury in rats

To study the protective effect of puerarin on the intestinal mucosal injury of SD rats induced by radiation and its molecular mechanism...

2022-10-26
【Animal modeling】-Effect of Lycium barbarum polysaccharide on tumor growth and metastasis in spontaneous breast cancer MMTV-PyMT mice

【Animal modeling】-Effect of Lycium barbarum polysaccharide on tumor growth and metastasis in spontaneous breast cancer MMTV-PyMT mice

To investigate the effect of Lycium barbarum polysaccharide on the growth and metastasis of breast cancer using MMTV-PyMT mice as a breast cancer model...

2022-10-26
【Animal modeling】-Recombinant lentivirus-mediated LXRα RNA interference improves the function of rat fatty liver donor liver transplantation

【Animal modeling】-Recombinant lentivirus-mediated LXRα RNA interference improves the function of rat fatty liver donor liver transplantation

To investigate the effect and mechanism of LXRα RNA interference (RNAi) in improving liver function in rats with fatty liver after liver transplantation...

2022-10-26
【Animal modeling】-The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

【Animal modeling】-The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

This study was the first to evaluate the lipid-lowering effect of adding citrus polymethoxyflavone powder to biscuits in a hyperlipidemia mouse model through the measurement of lipid metabolism experimental indicators, aiming to provide a new functio...

2022-10-26
【Animal Modeling】-Study draws a map of human hematopoietic stem cells from hematopoietic endothelium to birth

【Animal Modeling】-Study draws a map of human hematopoietic stem cells from hematopoietic endothelium to birth

Researchers such as Hanna K. A. Mikkola and Vincenzo Calvanese of the University of California, Los Angeles, collaborated to map human hematopoietic stem cells from the hematopoietic endothelium to birth...

2022-10-26
【Animal modeling】-Establishment and application of multiplex PCR method for four pathogens in experimental animals

【Animal modeling】-Establishment and application of multiplex PCR method for four pathogens in experimental animals

To establish a multiplex PCR method for the rapid detection of four experimental animal pathogens, Pasteurella multocida, Bordetella bronchiscus, Mycoplasma and Klebsiella pneumoniae...

2022-10-26
【Animal modeling】-Protective effect of γ-secretase inhibitor on white matter damage in neonatal rats induced by hyperoxia exposure

【Animal modeling】-Protective effect of γ-secretase inhibitor on white matter damage in neonatal rats induced by hyperoxia exposure

To investigate the effect of γ-secretase inhibitor on white matter damage in neonatal mice induced by atmospheric pressure and high concentration oxygen exposure...

2022-10-26
【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

To establish an in vitro model of intestinal epithelial cells—small intestinal organoid culture system, and to explore its related pathological detection techniques, so as to provide a convenient platform for the in vitro research of intestinal-relat...

2022-10-26
【Animal Modeling】-Effect of bis(2-ethyl)hexyl phthalate exposure during pregnancy on the growth and development of mouse placenta

【Animal Modeling】-Effect of bis(2-ethyl)hexyl phthalate exposure during pregnancy on the growth and development of mouse placenta

To observe the effects of DEHP exposure on placental growth and development, the number of uNK cells at the maternal-fetal interface and angiogenesis in mice by exposure to di(2-ethyl)hexyl phthalate (DEHP) during pregnancy...

2022-10-26
【Animal modeling】-Effect of prostacyclin E1 on hepatic fibrosis in rabbits after hepatic arterial lipiodol embolization

【Animal modeling】-Effect of prostacyclin E1 on hepatic fibrosis in rabbits after hepatic arterial lipiodol embolization

To investigate the effect of prostacyclin E1 on the mRNA expression levels of Smad2 and Smad4 in rabbits with hepatic fibrosis after hepatic arterial lipiodol embolization...

2022-10-26
【Animal modeling】-phenotype and pathological observation of leptin receptor gene knockout SD rats

【Animal modeling】-phenotype and pathological observation of leptin receptor gene knockout SD rats

To observe various parameters of the leptin receptor gene knockout rat model of obesity, metabolic syndrome and prediabetes established by CRISPR/Cas9 technology, and to provide a more ideal basis for the molecular mechanism research of metabolic dis...

2022-10-26
【Animal modeling】-Mechanism of transient receptor potential channel C1 in airway remodeling in guinea pig asthma and the intervention effect of budesonide

【Animal modeling】-Mechanism of transient receptor potential channel C1 in airway remodeling in guinea pig asthma and the intervention effect of budesonide

To explore the mechanism of TRPC1 ion channel in the evolution of airway remodeling and the intervention effect of budesonide by interfering with the expression of transient receptor potential channel C1 (TRPC1)...

2022-10-26