【Animal modeling】-Effect of postconditioning with dezocine on acute lung injury induced by intestinal ischemia-reperfusion in rats

To investigate the effect and possible mechanism of dezocine postconditioning on acute lung injury induced by intestinal ischemia-reperfusion in rats...

2022-10-26

How to construct animal models of type II diabetes in rats and mice?

How to construct animal models of type II diabetes in rats and mice? This question has been asked by many netizens, so today Zhonghong Boyuan will give you a technical sharing....

2022-10-26

[Animal Modeling]-Mouse stem cells can form "embryonic" structures in vitro

A team of European scientists published a medical paper in the British journal Nature, claiming that they only used mouse stem cells to cultivate structures similar to early embryos in petri dishes....

2022-10-26

【Animal Modeling】-Depression-like behavioral changes in male and female rats induced by restraint stress of different durations

To investigate the effects of chronic restraint stress of different restraint durations on the depression-like behavior of male and female SD rats, and to provide a basis for the selection of experimental animals\\\' gender and experimental duration ...

2022-10-26

【Animal Modeling】- Establishment of Swimming Endurance Experimental System in Mice and Verification of Anti-fatigue Effect of Rhodiola rosea

To establish a mouse swimming endurance experimental system, explore new indicators for evaluating the swimming endurance of mice, and use this system to verify the effect of Rhodiola rosea on the endurance of mice...

2022-10-26

[Animal modeling] - Construction and evaluation of two models of obese polycystic ovary syndrome with insulin resistance in rats

To establish an animal model of obese polycystic ovary syndrome (PCOS) with insulin resistance by two different ways combined with high-fat diet, and compare its endocrine and metabolic characteristics...

2022-10-26

[Animal modeling] - Establishment of a mouse model of abdominal aortic aneurysm and analysis of its histological characteristics

To establish an abdominal aortic aneurysm model in C57BL/6J mice by perfusion of porcine trypsin and evaluate its pathological changes...

2022-10-26

【Animal modeling】-Effect of dexmedetomidine on renal function and tight junction protein expression in septic rats

To investigate the effect of dexmedetomidine on renal function and tight junction protein expression in septic rats...

2022-10-26

【Animal modeling】-The expression and ultrastructural observation of kidney-yang deficiency-related mRNA in the hypothalamus of Lewis rats

To further study the kidney-yang deficiency constitution of Lewis rats by observing the gene expression and ultrastructure related to kidney-yang deficiency in the hypothalamus of Lewis rats...

2022-10-26

【Animal modeling】-C57-ras transgenic mouse model hybrid growth and development characteristics of the first generation of CB6F1

To determine the growth and development characteristics of the self-established transgenic carcinogenicity model C57-ras mice and BALB/c mice for one generation, and to provide basic data for the commercial supply of this model...

2022-10-26

【Animal modeling】-Comparative study on bone growth in rats after long-term exposure to low-fluoride aluminum and short-term high-fluoride aluminum exposure

To observe the effects of different doses of fluoride and aluminum combined with the duration of intake on longitudinal bone growth and bone metabolism in rats...

2022-10-26

【Animal Modeling】-Skin cells come from genetically modified pigs

Recently, the US Food and Drug Administration (FDA) approved XenoTherapeutics to initiate the first clinical trial of xenotransplantation...

2022-10-26

【Disease animal model】-induced atopic dermatitis animal model

The small molecule hapten combines with proteins in the body to form a complete antigen, which is absorbed by Langerhans cells. The corresponding antigen is presented to T cells and activated, and contact dermatitis occurs again...

2022-10-24

【Animal Modeling】-Experimental study of cabozantinib in blocking Listeria monocytogenes infection in mice

To investigate the possibility of cabozantinib, a c-Met receptor tyrosine kinase inhibitor, as a novel drug against Listeria monocytogenes infection...

2022-10-24

【Animal Modeling】-Study on changes in the number and traits of cardiac fibroblasts in early postnatal mice

Cardiac fibroblasts account for more than 50% of cardiac cells and play an important role in cardiac physiology and pathology. The 7th day after birth is a turning point when the heart loses its ability to regenerate. This study aimed to study the ch...

2022-10-24

【Animal modeling】- PERV-env gene cloning and tissue expression profiling in Guangxi Bama miniature pigs

To clone part of PERV-env gene of Guangxi Bama miniature pig, and study its expression difference in different tissues...

2022-10-24