[Animal modeling] - carbon tetrachloride induces inbred line C57BL/6 mice to establish liver fibrosis model

To compare the effects of different doses of carbon tetrachloride on the induction of liver fibrosis in inbred C57BL/6 mice, so as to establish a stable liver fibrosis model...

2022-11-02

[Animal modeling] - Characteristics of cardiac structure, function and pathological process of pressure overload heart failure mouse model

to establish a mouse heart failure model and evaluate the characteristic changes of cardiac function and structure in the course of disease development by ultrasonic imaging and pathological techniques...

2022-11-02

[Animal modeling] - LPS induced inflammation model of fibroblast like synoviocytes in knee joint of SD rats and its characteristics

To establish the primary culture method of normal knee synovial cells in Sprague Dawley (SD) rats and the inflammation model of fibroblast like synovial cells induced by lipopolysaccharide...

2022-11-02

[Animal modeling] - Establishment and applicability evaluation of animal model of pelvic organ prolapse

To establish a rat model that can reflect the similar pathological changes of sacral ligaments in patients with pelvic organ prolapse, and to explore the effects of increasing the intensity of birth injury and simulating menopause on the pathology of...

2022-11-02

[Animal modeling] - Comparative study of three types of extrahepatic cholestasis models in rats

To evaluate the advantages and disadvantages of three surgical models of extrahepatic cholestasis in rats by serology, imaging and pathology...

2022-11-02

[Animal modeling] - Establishment of a rat model of coronary heart disease with Qi deficiency and blood stasis syndrome

To explore the modeling method of CHD model with syndrome of Qi deficiency and blood stasis by analyzing the pathology, etiology, tongue manifestation of the compound model and the relationship with prostacyclin and thromboxane A2...

2022-11-02

[Animal modeling] - Establishment of a mouse model of lung metastasis and recurrence after bone marrow injection

to establish the model of lung metastasis and postoperative recurrence by bone marrow injection, and to reveal the superiority and feasibility of bone marrow injection model, so as to provide a new research basis for the study of lung metastasis of m...

2022-11-02

[Animal modeling] - Study on the mechanism of jujuboside in alleviating Alzheimer's disease model mice

To investigate the mechanism of jujuboside (ZSS) in alleviating sevoflurane anesthesia in 9-month-old APP/PS1/tau transgenic mice with Alzheimer disease...

2022-11-02

[Animal modeling] - Experimental study on establishing rat obesity model with high calorie diet

To observe the effect of establishing rat obesity model with high calorie diet, and the difference between the two kinds of rats, and compare different obesity evaluation methods and obesity sensitive animal screening methods, so as to provide refere...

2022-11-01

[Animal modeling] - Establishment of salt sensitive hypertensive mouse model

To establish a salt sensitive hypertensive mouse model and validate the model with nifedipine...

2022-11-01

[Animal modeling] - Construction and application of an improved rat skull defect animal model

To explore the ideal method of constructing rat skull defect model and improve the success rate of bone defect animal model...

2022-11-01

[Animal modeling] - Comparative study on the construction of high altitude pulmonary edema model in SD rats under different hypoxia stress

To study the effects of different hypoxia stress modes on the establishment of high altitude pulmonary edema model...

2022-11-01

[Animal modeling] - Establishment of premature ovarian failure model induced by chemotherapy in rats by intraperitoneal injection of different doses of cisplatin

To explore the method of establishing the model of chemotherapy-induced premature ovarian failure in rats by intraperitoneal injection of different doses of cisplatin (CP)...

2022-11-01

[Animal modeling] - Establishment of a mouse model of chronic thrombosis induced by carrageenan

To screen the conditions of chronic thrombosis model in mice by continuous intraperitoneal injection of carrageenan solution with different concentrations...

2022-11-01

[Animal modeling] - establish an animal model of human intestinal flora of Alzheimer's disease

To obtain a mouse model of human intestinal flora of Alzheimer\'s disease by oral fecal bacteria transplantation, and evaluate the model by bioinformatics, histopathology and other methods...

2022-11-01

[Animal modeling] - Application analysis of 274 rheumatoid arthritis animal models based on data mining

To study the modeling factors of rheumatoid arthritis animal models, and provide methodological reference for improving the success rate of modeling and evaluating the effectiveness of tested drugs...

2022-11-01