[Animal modeling] - Establishment and rapid detection of animal model of immunosuppressed mice

To establish an animal model of KM mice with low immunity, and to identify the establishment of the animal model by a simple and rapid method...

2022-11-02

[Animal modeling] - Application analysis of asthma animal model based on data mining

To analyze the modeling factors of asthma animal models, and to provide methodological reference for improving the success rate of modeling and effectively evaluating the tested drugs...

2022-11-02

[Animal modeling] - Infection of TNF by Listeria monocytogenes α Establishment and application of humanized mouse model

To evaluate TNF ⁃ α Susceptibility of host to listeria monocytogenes infection after intervention of monoclonal antibody...

2022-11-02

[Animal modeling] - Establishment and evaluation of rat model of chronic obstructive pulmonary disease

To establish a rat model of chronic obstructive pulmonary disease (COPD) by smoking, protease infusion and a combination of the two methods, and evaluate the effect of the model from the level of inflammation, imaging and pathology, and compare the t...

2022-11-02

[Animal modeling] - Study on the regulatory effect and mechanism of silencing miRNA-16 on immune function of pulmonary tuberculosis model mice

To study the regulatory effect of silent miR-16 on immune function of pulmonary tuberculosis model mice and its mechanism...

2022-11-02

[Animal modeling] - Establishment of rabbit model of myocardial iron overload and study on iron deposition rule

To explore the method of making animal model of myocardial iron deposition and the relationship between heart and liver...

2022-11-02

[Animal modeling] Experimental observation on evaluation points of blood glucose intervention in type 2 diabetes mouse model

To observe the changes of blood glucose in type 2 diabetes mouse model, and explore the feasibility of blood glucose 2 hours after meal as a blood glucose intervention evaluation point...

2022-11-02

[Animal modeling] - Observation on anxiety and depression like emotional behavior induced by chronic inflammatory pain model rats

To dynamically observe the change of pain emotion in rats with chronic inflammatory pain induced by Freund\'s complete adjuvant (CFA), and explore the time difference of anxiety and depression in rats with chronic inflammatory pain...

2022-11-02

[Animal modeling] - Analysis of magnetic resonance spectroscopy and ultrastructure in hippocampus of APP/PS1 double transgenic AD model mice

To observe the relationship between the changes of metabolites in the hippocampus of APP/PS1 transgenic mice and the ultrastructural pathological changes, so that the APP/PS1 transgenic mice can be better used in the experimental study of Alzheimer\'...

2022-11-02

[Animal modeling] - Study on the regulatory effect of tacrolimus on spinal cord injury model rats based on NF kB/JNK signal pathway

To investigate the therapeutic effect of tacrolimus on spinal cord injury in rats and its regulation on NF kB/JNK signal pathway...

2022-11-02

[Animal modeling] - Preparation of alcoholic cardiomyopathy mouse model by liquid feed

To establish a mouse model of alcoholic cardiomyopathy (ALCM) with liquid feed, and provide a good animal model for the study of the mechanism of ALCM...

2022-11-02

[Animal modeling] - Protective effect of anesthesia on the establishment of severe traumatic hemorrhagic shock model in rats

To establish a modified model of severe traumatic hemorrhagic shock in rats and investigate the protective effect of anesthesia on the establishment of STHS rat model...

2022-11-02

[Animal modeling] - Evaluation and research progress of common behavior paradigms in the model of mother infant separation

As an important way of early social deprivation, separation of mother and infant has always been a classic animal model to study the adverse effects of early life stress on individual physiology and psychology...

2022-11-02

[Animal modeling] - Construction of a nude mouse model of clear cell renal cell carcinoma and study on its targeted drug sensitivity

To establish a tumor animal model with clear cell renal cancer cells from patients, and to detect the sensitivity of ccRCC PDCs to molecular targeted drugs, so as to provide theoretical and experimental basis for clinical diagnosis and treatment...

2022-11-02

[Animal modeling] - Comparative study on establishing allergic conjunctivitis model in mice under different conditions

To establish allergic conjunctivitis mouse models under different antigens, different excitation pathways and different mouse weeks, and to screen the best sensitization conditions by comparing the immune response status, so as to provide new ideas a...

2022-11-02

[Animal modeling] - Establishment of long-term depression mouse model and observation of behavioral and neuropathological characteristics

To construct a new model of long-term depression in mice, and compare the advantages and disadvantages of this model with common depression models...

2022-11-02