[Animal modeling] - Comparison of the application of two mycobacterium tuberculosis culture methods in the infection model experiment of tuberculosis mice

To simultaneously verify the therapeutic effect of rifampicin in the tuberculosis infected mouse model by using two mycobacterium tuberculosis culture methods, and to explore the application value of BACTEC MGIT960 culture system in the tuberculosis ...

2022-11-03

[Animal modeling] - Establishment of levofloxacin resistant mouse model

To detect the effect of low concentration of levofloxacin on the pneumonia model of mice infected with Pseudomonas aeruginosa (PA), and explore the method of levofloxacin resistance...

2022-11-03

[Animal modeling] - Comparison of insulin resistance atherosclerosis models between white haired black eye rabbits and Japanese big ear rabbits

To investigate the phenotypic difference and pathological mechanism of insulin resistance atherosclerosis models in white haired black eyed (WHBE) rabbits and Japanese white eared (JW) rabbits...

2022-11-03

[Animal modeling] - Establish a mouse model with seasonal influenza virus H3N2 mouse adaptation strain

To establish a mouse model with the seasonal influenza virus H3N2 mouse adaptation strain, and to explain the molecular mechanism of the change in the pathogenicity of the adaptation strain...

2022-11-03

[Animal modeling] - Establishment of BALB/c nude mice myeloid leukemia model by tail vein injection of M1 cells

To construct M1 leukemia model with BALB/c nude mice...

2022-11-03

[Animal modeling] - Establishment and evaluation of a mouse model of endogenous infection induced by intestinal dissemination

To establish a mouse model of endogenous infection induced by intestinal dissemination, so as to provide a reliable experimental model for studying the mechanism of intestinal microecology and endogenous infection...

2022-11-03

[Animal modeling] - Establishment and preliminary analysis of hyperlipidemia cynomolgus monkey model

To establish a hyperlipidemic cynomolgus monkey model similar to human disease characteristics, and provide an ideal animal model for the research and development of lipid-lowering drugs (especially biological lipid-lowering drugs)...

2022-11-03

[Animal modeling] - Establishment of allergic asthma model in mice aggravated by respiratory administration of antibiotics

The mechanism of traditional Chinese medicine (TCM) treating diseases by regulating the flora has been gradually discovered, and the asthma model of respiratory tract flora disorder caused by antibiotics has been explored to provide a suitable model ...

2022-11-03

[Animal modeling] - sterile APPswe/PS1 Δ Establishment of E9 Double Transgenic Mouse Model and Preliminary Observation of Plaque Changes

To establish aseptic APPswe/PS1 using the method of cesarean section purification Δ E9 (PAP) double transgenic mouse model and preliminary observation of plaque deposition in animal brain, providing a new animal model for studying the relationship be...

2022-11-03

[Animal modeling] - Using orthogonal test to optimize the establishment of rat's conditioned fear memory model

To optimize the best experimental parameters for establishing the rat model of conditioned fear memory by using orthogonal test, and to find the best experimental conditions...

2022-11-03

[Animal modeling] - Analysis of Mozart K448 sonata high frequency sound wave on the intervention treatment of mouse depression model

To establish the depression model of C57BL/6 mice and preliminarily explore the effect of high frequency sound wave in Mozart K448 sonata on improving the depression symptoms of C57BL/6 mice...

2022-11-03

[Animal modeling] - Comparison of two methods for preparing rabbit models of cardiac arrest

To compare the characteristics of physiological indexes of two rabbit models of cardiac arrest induced by potassium chloride and transesophageal chest wall electric fibrillation during cardiopulmonary resuscitation...

2022-11-03

[Animal modeling] - Construction of bioluminescence human liver cancer in situ model in nude mice

To construct a tumor bearing nude mouse model of human hepatoma cell line in situ by using human hepatoma cell line (HCCLM3 Luc) stably expressing luciferase reporter gene...

2022-11-03

[Animal modeling] - Study on rat model of atherosclerosis (Qi stagnation and blood stasis syndrome) combined with disease and syndrome

To construct a rat model of atherosclerosis combining disease and syndrome, and provide an evaluation tool for the pharmacodynamic study of corresponding Chinese herbal compound...

2022-11-03

[Animal modeling] Establishment of inflammation model of BALB/c mice infected with influenza A virus

To analyze the pathogenicity of influenza A virus with mouse inflammatory animal model...

2022-11-03

[Animal modeling] - Establishment of mastitis model in mice infected with Staphylococcus aureus and changes of IL-2 and IL-4

To investigate the changes of inflammatory factors interleukin 2 (IL-2) and interleukin 4 (IL-4) in the pathogenesis of mastitis in mice...

2022-11-03