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【Animal Modeling】-How to establish an experimental animal model of chronic obstructive pulmonary disease?

【Animal Modeling】-How to establish an experimental animal model of chronic obstructive pulmonary disease?

Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide...

2022-01-31
【Animal Modeling】-How to improve the method of constructing myocardial ischemia-reperfusion injury model?

【Animal Modeling】-How to improve the method of constructing myocardial ischemia-reperfusion injury model?

Improved method for comprehensive evaluation of rat myocardial ischemia-reperfusion injury model...

2022-01-31
【Animal Modeling】-How to compare different animal models of Graves disease?

【Animal Modeling】-How to compare different animal models of Graves disease?

The purpose of this study is to start from the immune-related mechanisms of Graves disease, compare our previous studies of mouse and macaque GD animal models, explore the differences in the characteristics of different animal GD models, and based on...

2022-01-31
When will the first CRISPR/Cpf1 gene editing of rabbit and pig models be completed? -【Animal Modeling】

When will the first CRISPR/Cpf1 gene editing of rabbit and pig models be completed? -【Animal Modeling】

Lai Liangxue’s group from the Guangzhou Institute of Biomedical Sciences, Chinese Academy of Sciences published a new gene editing study in the international journal Cell and Molecular Life Sciences, \\\\\\\"Engineering CRISPR/Cpf1withtRNA to pr...

2022-01-31
【Animal Modeling】-How to build an animal model of human intestinal flora of Alzheimer\\

【Animal Modeling】-How to build an animal model of human intestinal flora of Alzheimer

Fecal bacterial transplantation was used to obtain human flora-related (HFA) model mouse Alzheimer\\\'s disease through oral route, and the model was evaluated through bioinformatics, histopathology and other methods...

2022-01-31
【Animal Modeling】-What is the difference between spontaneous and induced type 2 diabetes mouse models?

【Animal Modeling】-What is the difference between spontaneous and induced type 2 diabetes mouse models?

Compare the differences in glucose metabolism, insulin resistance and inflammation between spontaneous and induced type 2 diabetic mouse models...

2022-01-31
【Animal Modeling】-Single intraosseous injection of simvastatin promotes normalization of breast cancer tumor blood vessels in mice

【Animal Modeling】-Single intraosseous injection of simvastatin promotes normalization of breast cancer tumor blood vessels in mice

To study the effect of a single intraosseous injection of simvastatin on the vascular structure and function of breast cancer tumors in mice...

2022-01-31
【Animal Modeling】-Post-traumatic stress disorder model

【Animal Modeling】-Post-traumatic stress disorder model

Establish a model of post-traumatic stress disorder through single long-term stress (SPS), and observe the effect of orphan feeding on SPS model rats...

2022-01-31
【Animal Modeling】-How to build an animal model of choroidal and retinal neovascularization?

【Animal Modeling】-How to build an animal model of choroidal and retinal neovascularization?

The development of animal models of choroidal neovascularization (CNV) and retinal neovascularization (RNV) contributes to the understanding of biology in this situation...

2022-01-31
【Animal Modeling】-How to establish a Hr gene knockout mouse model?

【Animal Modeling】-How to establish a Hr gene knockout mouse model?

Establish knockout mice and study the function of hairless gene (Hr) in detail...

2022-01-31
【Animal Modeling】-Light Thrombus Stroke Model

【Animal Modeling】-Light Thrombus Stroke Model

Stroke has a high fatality rate, disability rate and recurrence rate, which is an insurmountable disease for human beings. It is mainly divided into hemorrhagic stroke and ischemic stroke. The latter accounts for 80% of all strokes...

2022-01-31
【Animal Modeling】-Naphthoquine induces central nervous system and hepatic vascular center toxicity in Beagle dogs

【Animal Modeling】-Naphthoquine induces central nervous system and hepatic vascular center toxicity in Beagle dogs

He was approximately 14 months old at the start of the administration and weighed 7.8 to 10.1 kg. Vehicle control group (0 mg/kg/day, 1 female and 1 male), low-dose group (2 mg/kg/day, 1 female and 1 male) and medium-dose group (10 mg/kg/day, 1 femal...

2022-01-31
【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

To investigate the effect of low selenium diet on liver and kidney in rats, and the role of macrophage polarization to M1 and M2 in liver and kidney fibrosis...

2022-01-28
【Animal Modeling】-Glucagon-like polypeptide-1 improves learning and memory ability in type 2 diabetic rats

【Animal Modeling】-Glucagon-like polypeptide-1 improves learning and memory ability in type 2 diabetic rats

To observe the improvement effect of diabetes treatment drug glucagon-like peptide-1 (GLP-1) on learning and memory dysfunction in diabetic rats...

2022-01-28
【Animal modeling】-Effect of hypoxic preconditioning on the formation of endometriotic lesions in rats

【Animal modeling】-Effect of hypoxic preconditioning on the formation of endometriotic lesions in rats

To understand the effect of hypoxic preconditioning on the formation of ectopic lesions in a rat model of endometriosis, so as to further clarify the molecular mechanism of the occurrence and development of EMs, so as to provide new ideas for its pre...

2022-01-28
【Animal Modeling】-Depression-like behavioral changes in male and female rats induced by restraint stress of different durations

【Animal Modeling】-Depression-like behavioral changes in male and female rats induced by restraint stress of different durations

To investigate the effects of chronic restraint stress of different restraint durations on the depression-like behavior of male and female SD rats, and to provide a basis for the selection of experimental animals\\\' gender and experimental duration ...

2022-01-28