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【Animal Modeling】-How to establish a nude mouse model of human prostate cancer xenograft?

【Animal Modeling】-How to establish a nude mouse model of human prostate cancer xenograft?

Establish a human-derived xenograft (PDX) model of prostate cancer and evaluate the anti-tumor efficacy of various treatment options?...

2022-02-01
【Animal modeling】-Effects of bis(2-ethylhexyl) phthalate exposure during pregnancy on growth and development of mouse placenta

【Animal modeling】-Effects of bis(2-ethylhexyl) phthalate exposure during pregnancy on growth and development of mouse placenta

Through exposure to bis(2-ethylhexyl) phthalate (DEHP) during pregnancy, observe the effects of DEHP exposure on the growth and development of mouse placenta, the number of uNK cells at the maternal-fetal interface, and angiogenesis in vivo...

2022-02-01
【Animal Modeling】-Determination of Microbial Diversity of Common Cotton-eared Marmoset Manure Based on High-throughput Sequencing Technology

【Animal Modeling】-Determination of Microbial Diversity of Common Cotton-eared Marmoset Manure Based on High-throughput Sequencing Technology

Apply high-throughput sequencing technology to analyze the structure and composition of the fecal flora of common cotton-eared marmoset monkeys, and lay the foundation for the further development and utilization of new experimental animals...

2022-02-01
[Animal Modeling]-Hemorrhoids Magnetizing Ointment to Mouse Model of Hemorrhoids

[Animal Modeling]-Hemorrhoids Magnetizing Ointment to Mouse Model of Hemorrhoids

To study the protective effect of hemorrhoids magnetic ointment on mice with hemorrhoids induced by acetic acid...

2022-02-01
【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

Explore the electroacupuncture synaptic plasticity and microglia polarization in rats with focal cerebral ischemia, and detect the expression of miR-21/signal transducer and activator of transcription 3 (STAT3) pathway...

2022-02-01
【Animal Modeling】-Von Willebrand Disease Mini Pig Model

【Animal Modeling】-Von Willebrand Disease Mini Pig Model

A research team led by Zhou Qi, a researcher at the Institute of Zoology, Chinese Academy of Sciences, obtained vWF knockout pigs for the first time using CRISPR/Cas9 technology and established a miniature pig model of von Willebrand disease...

2022-02-01
【Animal Modeling】-Effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge in medulla oblongata of newborn rats

【Animal Modeling】-Effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge in medulla oblongata of newborn rats

To investigate the effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge activity (RRDA) in the medulla oblongata slices of offspring of newborn rats...

2022-02-01
Skin stem cells cultivated human 【mini】hearts, which will replace animal experiments in the future

Skin stem cells cultivated human 【mini】hearts, which will replace animal experiments in the future

American scientists have genetically recombined pluripotent stem cells extracted from human skin and cultivated a microventricle with human heart cells...

2022-02-01
【Animal Modeling】-The effect of estrogen and progesterone on the induced differential expression of αvβ3 in bovine endometrial epithelial cells in vitro

【Animal Modeling】-The effect of estrogen and progesterone on the induced differential expression of αvβ3 in bovine endometrial epithelial cells in vitro

To study the changes in the induced differential expression of integrin αvβ3 gene in bovine uterine epithelial cells cultured in vitro, in order to provide a reference for exploring the marker protein of bovine uterine receptivity?...

2022-02-01
[Animal Modeling]-The combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

[Animal Modeling]-The combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

To explore the effect of combined action of estrogen and androgen on blood lipid level and coagulation function in hyperlipidemia mice...

2022-02-01
【Animal Modeling】-Hr gene knockout mouse model construction and phenotype analysis

【Animal Modeling】-Hr gene knockout mouse model construction and phenotype analysis

Establishment of knockout mice for detailed study of the function of hairless genes (Hr)...

2022-02-01
【Animal Modeling】-Preliminary Study on the Effect of Lipopolysaccharide on Naked Mole Lung Tissue

【Animal Modeling】-Preliminary Study on the Effect of Lipopolysaccharide on Naked Mole Lung Tissue

To observe and analyze the effects of lipopolysaccharide on the morphological structure and pathological indexes of naked mole rats’ lung tissues, and to preliminarily explore whether the naked mole rats are resistant to LPS...

2022-02-01
【Animal Modeling】-Lentivirus-mediated shRNA targeting survivin gene inhibits the growth of endometrium in the abdominal cavity of nude mice

【Animal Modeling】-Lentivirus-mediated shRNA targeting survivin gene inhibits the growth of endometrium in the abdominal cavity of nude mice

To study the effect of lentivirus-mediated survivin gene specific short hairpin RNA (shRNA) on the growth of human endometrium implanted in the abdominal cavity of nude mice...

2022-02-01
【Animal Modeling】-What is the source tumor tissue xenograft model?

【Animal Modeling】-What is the source tumor tissue xenograft model?

The tumor transplantation model established by transplanting the patient\\\\\\\'s tumor tissue into immunodeficient mice retains the biological characteristics of the primary tumor, but the matrix components of the tumor tissue are passaged in the mi...

2022-02-01
【Animal Modeling】-Small Ubiquitin-like Modifier Protease 3 Regulates Autophagy in Mouse Alveolar Type Ⅱ Epithelial Cells

【Animal Modeling】-Small Ubiquitin-like Modifier Protease 3 Regulates Autophagy in Mouse Alveolar Type Ⅱ Epithelial Cells

To investigate the regulatory effect and molecular mechanism of small ubiquitin-like modifier-specific protease 3 on autophagy in mouse lung tissue cells...

2022-02-01
【Animal Modeling】-Ⅲ Type Allergic Reaction Model

【Animal Modeling】-Ⅲ Type Allergic Reaction Model

Replication method Dissolve rabbit anti-bovine serum albumin antiserum in PBS, pH 7.2, put 100μl into rabbit eyelid conjunctiva four times...

2022-02-01