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【Animal Modeling】-The nutritional requirements of experimental rabbits

【Animal Modeling】-The nutritional requirements of experimental rabbits

The feed contains about 15% protein. Among the essential amino acids, arginine is particularly important for rabbits and is the first restrictive amino acid. Therefore, arginine and lysine must be supplemented in the rabbit’s diet....

2022-02-03
【Animal Experiment】-Establishment of Morphine Dependence Rat Model

【Animal Experiment】-Establishment of Morphine Dependence Rat Model

Purpose   (1) Familiar with the method of establishing morphine-dependent rat model, and copy the morphine-dependent rat model.    (2) Observe and score the withdrawal symptoms of morphine-dependent rats to determine whether a morphine-dependen...

2022-02-03
【Animal Model】- Rat model of chronic obstructive pulmonary disease

【Animal Model】- Rat model of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a chronic respiratory system disease. Its airflow limitation is characterized by inflammation and the concentrated effect of the lungs on harmful gases (such as cigarette smoke and harmful particles (es...

2022-02-03
【Animal Modeling】-Induced bladder cancer animal model

【Animal Modeling】-Induced bladder cancer animal model

There are two ideal animal carcinogenic chemicals: N-butyl-N-(4-hydroxybutane 1). -Nitrosamines, BBN) and N*methyl-N-nitrosourea (N-methyl-N-nitrosourea, MNU) are representative nitroso compounds and N-[4-(5 -Nitro-2-furyl)-2, -thiazolyl]carboxamide...

2022-02-02
【Animal Modeling】-Human ovarian cancer transplanted tumor model in nude mice

【Animal Modeling】-Human ovarian cancer transplanted tumor model in nude mice

The transplanted tumor model of human ovarian cancer in nude mice is an ideal carrier for ovarian cancer research. It is used for the etiology, etiology, biological characteristics of human ovarian cancer, radioimmunoimaging diagnosis, chemotherapy d...

2022-02-02
【Animal Modeling】-Radiation Pulmonary Fibrosis Model

【Animal Modeling】-Radiation Pulmonary Fibrosis Model

Radiotherapy is one of the main treatment methods for breast tumors. Radiation pulmonary fibrosis is a common lung injury repair change after radiotherapy of breast tumors, which may lead to irreversible lung dysfunction...

2022-02-02
How to measure the air velocity of laboratory animals?

How to measure the air velocity of laboratory animals?

The experimental equipment is operating under conditions close to the design load, and the measurement continues for more than 48 hours...

2022-02-02
What are the SPF animal feeding management requirements and conditions?

What are the SPF animal feeding management requirements and conditions?

Except for pathogens that need to be excluded from clean animals, there are no major potential infectious diseases or pathogens that cause conditional diseases and interfere with scientific experiments...

2022-02-02
How to install laboratory animal electrical and automatic control facilities?

How to install laboratory animal electrical and automatic control facilities?

1) Issue   1. The electrical load of the production area (animal experiment area) of the barrier environment facility should be level 2 or higher. Or prepare a backup power supply.   2, barrier environment facilities should install special powe...

2022-02-02
【Animal Modeling】-Gene modified animal model of bladder cancer

【Animal Modeling】-Gene modified animal model of bladder cancer

Transgenic animal models of bladder cancer can be divided into microinjection, retroviral infection and embryonic stem cell method through gene transfer. The microinjection method is more mature. The purified target gene fragment is microinjected int...

2022-02-02
【Animal Modeling】-Oleic acid induced acute renal failure model in rats

【Animal Modeling】-Oleic acid induced acute renal failure model in rats

Oleic acid is a highly toxic fatty acid. When oleic acid is injected into the left renal artery, renal tubular epithelial cells swell and die, interstitial edema, intravascular renal ischemia and severe renal microcirculation. It is impaired and rena...

2022-02-02
What are the environmental requirements for laboratory animals?

What are the environmental requirements for laboratory animals?

The experimental animal environment refers to a special artificial place where animals are kept in a limited space controlled by humans and grow, reproduce and experiment according to human wishes. The environment outside the breeding room or animal...

2022-02-02
How to measure the temperature and humidity of laboratory animals?

How to measure the temperature and humidity of laboratory animals?

The measurement shall be performed after the completion of the facility, after 48 hours of operation of the air conditioning system or during the normal operation of the facility. During the measurement process, the breeding/breeding area and experim...

2022-02-02
【Animal Modeling】-Deoxycorticosterone salt-induced hypertension model

【Animal Modeling】-Deoxycorticosterone salt-induced hypertension model

Intraperitoneal injection of diazyl am 5 mg/kg and ketamine 50 mg/kg, anesthetize 100-150 g male SD rats, and perform left nephrectomy through midline incision...

2022-02-02
【Animal Modeling】- Kidney Outsourcing Hypertension Model

【Animal Modeling】- Kidney Outsourcing Hypertension Model

Commonly used animals are adult SD or Wistar rats, 120-150g rats, anesthetized with diazepa 5mg/kg and ketamine 50mg/kg, prone position, fixed below the abdomen...

2022-02-02
【Animal Modeling】-Chemical Induced IBD Animal Model

【Animal Modeling】-Chemical Induced IBD Animal Model

Since the 1960s, the chemical induction method has been started very early, and has become the most mature and commonly used method for preparing IBD models. There are many types of chemical stimulants, such as acetic acid, sodium dextran sulfate, so...

2022-02-02