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【Animal modeling】-Isolation, culture and identification of goat alveolar macrophages

【Animal modeling】-Isolation, culture and identification of goat alveolar macrophages

To establish a high-purity method for the isolation and culture of alveolar macrophages to provide materials for the study of the biological characteristics of macrophages and the study of the survival mechanism of intracellular parasites...

2021-11-25
【Animal Modeling】-Based on the interaction of TRPV1 and P2X3, the regulation mechanism of peripheral pain in rats

【Animal Modeling】-Based on the interaction of TRPV1 and P2X3, the regulation mechanism of peripheral pain in rats

Observe the relationship between TRPV1 and P2X3 in peripheral rats, and partially clarify the sensory regulation mechanism of peripheral pain?...

2021-11-23
How to establish an animal model of lung cancer brain metastasis? -【Animal Modeling】

How to establish an animal model of lung cancer brain metastasis? -【Animal Modeling】

Provide a reliable modeling method for studying the mechanism of lung cancer brain metastasis...

2021-11-23
[Animal experiment]-Morphological observation of the tree shrew flagellate and its 18S rRNA gene analysis

[Animal experiment]-Morphological observation of the tree shrew flagellate and its 18S rRNA gene analysis

Morphological observation and genetic analysis of horse whip whip...

2021-11-23
[Animal Modeling]-Rat Model of Double Liver Transplantation

[Animal Modeling]-Rat Model of Double Liver Transplantation

In order to reduce the occurrence of small liver syndrome, transplant scientists have made many attempts to expand the size of the transplanted liver. Among them, dual-donor liver transplantation is one of the most effective methods. Receptor...

2021-11-23
【Animal Modeling】-Arrhythmia induced by coronary artery ligation in anesthetized rats

【Animal Modeling】-Arrhythmia induced by coronary artery ligation in anesthetized rats

Male rats weighing 250-450g were anesthetized with 3% sodium pentobarbital (40mg/kg) by intraperitoneal injection, fixed in the supine position, separated the carotid artery to record blood pressure, cut the skin in the middle of the neck, and separa...

2021-11-23
Mathematical model reveals that children are twice as capable of resisting COVID-19 as adults

Mathematical model reveals that children are twice as capable of resisting COVID-19 as adults

A new computational analysis shows that people under the age of 20 are half as likely to contract COVID-19 as adults, and they are less likely to infect others....

2021-11-23
【Animal Modeling】-Establishment of rat model of myocardial cell mitochondria injury caused by bupivacaine

【Animal Modeling】-Establishment of rat model of myocardial cell mitochondria injury caused by bupivacaine

Observe the changes of mitochondrial morphology and reactive oxygen species (ROS) production of bupivacaine cardiomyocytes under electrical stimulation, in order to establish an ideal bupivacaine poisoning rat cardiomyocyte model...

2021-11-23
[Animal Modeling]-How to establish a hypokalemic hypokalemic periodic paralysis model in mice?

[Animal Modeling]-How to establish a hypokalemic hypokalemic periodic paralysis model in mice?

Use gene knock-in CaV1.1-R528H mice to establish and evaluate the hypokalemic periodic paralysis model of hyperthyroidism...

2021-11-23
Fixed knee joint model in rats: joint bleeding accelerates cartilage degeneration

Fixed knee joint model in rats: joint bleeding accelerates cartilage degeneration

Trauma, ligament reconstruction surgery and bleeding disorders (such as hemophilia) can cause joint bleeding...

2021-11-23
Gene therapy can effectively treat Pap syndrome

Gene therapy can effectively treat Pap syndrome

Barth syndrome is a rare metabolic disease in male children and is caused by mutations in a gene called TAZ...

2021-11-23
[Animal Modeling]-Rat Model of Transplanted Tumor with Uterine Fibroids

[Animal Modeling]-Rat Model of Transplanted Tumor with Uterine Fibroids

Establish a tissue inhibitor transplantation immunosuppressive rat uterine fibroids model to provide a new animal model for the study of uterine fibroids...

2021-11-23
【Animal Modeling】-Non-human primate infection model

【Animal Modeling】-Non-human primate infection model

Reproduction method Collect adult rhesus monkeys, cynomolgus monkeys and bear monkeys with negative HAV, HBV, HCV, HDV and HEV 1 month before vaccination and 1 day before vaccination, and determine their normal ALT enzyme activity...

2021-11-23
Key genes that regulate cholesterol levels

Key genes that regulate cholesterol levels

Precision medicine can adjust the treatment plan according to the patient\\\'s unique gene sequence, but in order to achieve this accuracy (or develop new drugs), we need to know which genes are related to the disease...

2021-11-17
Scientists may use CRISPR technology to treat hemophilia

Scientists may use CRISPR technology to treat hemophilia

Hemophilia patients often live under stress and anxiety. The patient’s joints will break and decline prematurely, and once the body bleeds, it is difficult to stop the bleeding. Hemophilia patients lack the ability to produce clotting factors, so any...

2021-11-17
Antisense therapy can slow down Mouse virus disease in mice Antisense therapy can slow down Mouse virus disease in mice

Antisense therapy can slow down Mouse virus disease in mice Antisense therapy can slow down Mouse virus disease in mice

According to the latest report from JCI Insight, scientists using experimental methods have slowed the progression of scrapie (degenerative central nervous disease caused by viruses) in experimental mice and greatly extended the lives of rodents...

2021-11-17