Long-term effects of sublethal γ-ray irradiation on the hematopoietic immune function of mice

Observe the changes of hematopoietic and immune function indexes of C57BL/6J mice 6 months after 4Gy and 6Gy whole body irradiation...

2021-11-15

【Animal Modeling】-Animal Model of Retinal Neovascularization

Replication method (1) Place 7-day-old C57BL/6N mice in a 75% oxygen environment, control at room temperature (23±2) ℃, and return to the atmosphere after 5 days...

2021-11-15

【Animal Modeling】-Animal Model of Traumatic Articular Cartilage Damage Repair

　　Reproduction method Anesthetize 4-5 months old New Zealand rabbits with intraperitoneal ketamine of 50 mg/kg body weight, and then fix them on the surgical plate...

2021-11-15

【Animal Modeling】-Acute Ulcerative Colitis Induced by Acetic Acid Animal Model

Reproduction method Anesthetize adult male rats by intraperitoneal injection of sodium pentobarbital, fasting for 16 hours and depriving water, slowly insert the polyethylene catheter from the colon at 8 cm from the anus into 1.5 to 2 ml of 8% acetic...

2021-11-15

【Animal Modeling】-Preliminary Study on the Tolerance of Naked Mole Heart to 60Co γ-ray Radiation

Observe and analyze the changes in the morphology, structure and tissue biochemical indexes of Hadakadebanezumi\\\'s heart by 60Coγ-rays, and preliminary study the tolerance of Hadakadebanezumi\\\'s heart to 60Coγ-rays...

2021-11-15

【Animal Modeling】-How to build an animal model of inhalation of atmospheric fine particles?

Establish an animal model of physical injury caused by long-term inhalation of atmospheric particulate matter (PM2.5) aerosols...

2021-11-15

【Animal Modeling】-A 549 green fluorescent nude mouse model of lung adenocarcinoma

Establish a lung adenocarcinoma A549 model inoculated subcutaneously in green fluorescent nude mice to study the source of vascular endothelial cells in the process of lung adenocarcinoma tumor angiogenesis...

2021-11-12

【Animal Modeling】-Isolation and culture of primary tree shrew corneal stromal cells

To explore a simple and easy method to isolate and culture tree shrew corneal stromal cells in vitro quickly...

2021-11-12

【Animal Modeling】-Directed breeding and identification of Mfge8 knockout homozygous mice and its correlation with autoimmune diseases

To breed and identify Mfge8 knockout C57BL/6 mice, obtain homozygous (Mfge8-/-) mice, and compare the serological and histological changes of Mfge8-/- mice...

2021-11-12

【Animal Modeling】-Based on the Tet-On system to construct a lentiviral vector for the Alb promoter to regulate the expression of porcine uPA transgene

Using Tet-On gene expression regulation system to construct a lentiviral vector pLVX-Alb-TetOne-TRE-puPA-T2A-CopGFP(pLATTPUTG )...

2021-11-12

【Animal Modeling】-CRISPR/Cas9 system mediates reproduction and identification of Slc6a6 knockout rats

Use CRISPR/Cas9 technology to construct taurine transporter gene (solute carrier family 6 member 6, Slc6a6) knockout rats, breed and identify them, and provide a stable rat model for studying the effects of taurine deficiency on neurological diseases...

2021-11-12

[Animal Modeling]-Study on the tissue distribution of sialic acid receptors in dogs and their susceptibility to H3N2 subtype canine influenza virus

Determine the type and distribution of influenza virus receptors in different tissues and organs of dogs to verify the susceptibility of dogs to H3N2 subtype canine influenza virus...

2021-11-12

【Animal Modeling】-Establishment of waste heat recovery system of high-pressure steam sterilizer

Reduce the temperature of waste steam and waste water discharged from the high-pressure steam sterilizer through a heat exchanger, so that it can be discharged in the PVC pipe, and recover the heat energy in the discharged waste steam and waste water...

2021-11-12

[Animal modeling]-Myocardial tissue specific Isca1 knockout causes abnormal heart structure in newborn rats

Through magnetic resonance analysis and pathological analysis of myocardial tissue specific Isca1 knockout rats, explore the effect of myocardial specific Isca1 knockout on rat heart structure...

2021-11-12

【Animal Modeling】-Fancm gene knockout mice construction and phenotype analysis

Constructing Fanconi anemia pathway Fancm gene knockout mice to study the effect of Fancm gene deletion on the physiological functions of mice, especially the male reproductive organs...

2021-11-12

[Animal Modeling]-Construction of Bone Morphogenetic Protein 9 Gene Knockout Mice

Use CRISR/Cas9 technology to knock out the Bmp9 gene fragment in the mouse genome to construct a Bmp9 gene knockout mouse...

2021-11-12