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【Animal Modeling】-Using dual sgRNAs to construct miR-223 knockout mice

【Animal Modeling】-Using dual sgRNAs to construct miR-223 knockout mice

Construction of miR-223 knockout mice using dual sgRNAs...

2021-11-12
[Animal Modeling]-Screening EV71 pathogenicity-related genes through genetic diversity mice

[Animal Modeling]-Screening EV71 pathogenicity-related genes through genetic diversity mice

Screen the pathogenicity-related genes of enterovirus 71 through genetic diversity mouse resources, deeply understand the pathogenic mechanism of the virus, and provide the basis for clinical diagnosis, treatment and prognosis...

2021-11-12
[Animal modeling]-Pathological changes of bone, liver, kidney and brain tissue in fluorosis rats

[Animal modeling]-Pathological changes of bone, liver, kidney and brain tissue in fluorosis rats

To study the effect of sodium fluoride on the pathology of rat bone, brain, liver and kidney tissues...

2021-11-12
【Animal Modeling】-The effects of three anesthetics on the electrocardiogram of C57BL/6 male mice

【Animal Modeling】-The effects of three anesthetics on the electrocardiogram of C57BL/6 male mice

By comparing the effects of three conventional animal anesthetics on the ECG of C57BL/6 mice, explore the anesthetics that have less interference on the ECG of mice...

2021-11-12
[Animal Modeling]-Phenotype and Pathological Observation of SD Rats with Leptin Receptor Knockout

[Animal Modeling]-Phenotype and Pathological Observation of SD Rats with Leptin Receptor Knockout

To observe the various parameters of the leptin receptor gene knockout rat model with obesity, metabolic syndrome and pre-diabetes characteristics established by CRISPR/Cas9 technology, and to provide a more ideal model for the molecular mechanism re...

2021-11-12
【Animal Modeling】-Selenium-induced Cataract Model

【Animal Modeling】-Selenium-induced Cataract Model

Reproductive method Inject 0.16% sodium selenite solution into the abdominal cavity of 12-day-old pups weighing about 25g, weighing 0.26ml/kg, rat cataract...

2021-11-11
【Animal modeling】-miR-20b inhibits airway inflammation in asthmatic mice

【Animal modeling】-miR-20b inhibits airway inflammation in asthmatic mice

To explore the effect of miR-20b on airway inflammation in asthmatic mice...

2021-11-11
[Animal Modeling]-Human-derived xenograft nude mouse model of prostate cancer

[Animal Modeling]-Human-derived xenograft nude mouse model of prostate cancer

How to establish a human-derived prostate cancer xenograft (PDX) model and evaluate the anti-tumor effects of various treatment options?...

2021-11-11
Animal experiment of new diabetes drug succeeded

Animal experiment of new diabetes drug succeeded

A research team in the United States developed a new drug to control blood sugar, and it was successful in animal experiments. The researchers said that the study involves a hormone that occurs naturally in the human brain, which is expected to help...

2021-11-11
Effect of melittin on Th17/Treg balance and inflammation in collagen-induced arthritis rat model

Effect of melittin on Th17/Treg balance and inflammation in collagen-induced arthritis rat model

To explore the effect of melittin intervention on the regulation of Th17/Treg balance and joint inflammation in a rat model of collagen-induced arthritis...

2021-11-11
Pathological changes of important brain areas in rats with post-traumatic stress disorder after combined stimulation

Pathological changes of important brain areas in rats with post-traumatic stress disorder after combined stimulation

To study the pathological changes of important brain areas in rats with post-traumatic stress disorder after compound stimulation...

2021-11-11
Experimental study of SD rat portal hypertension animal model prepared by left branch ligation

Experimental study of SD rat portal hypertension animal model prepared by left branch ligation

  xplore whether simple ligation of the left portal vein can form stable portal hypertension and whether nitric oxide plays a corresponding role in it...

2021-11-11
【Animal Model】- Rat Artery Transplant Model

【Animal Model】- Rat Artery Transplant Model

  Allograft vascular disease (AV) limits the function and long-term survival of transplanted organs. This is the most pressing global issue in the field of organ transplantation...

2021-11-11
The establishment and mechanism of BALB/c mouse total hysterectomy model

The establishment and mechanism of BALB/c mouse total hysterectomy model

  Establish an experimental animal model of BALB/c mouse total hysterectomy, and explore and analyze the characteristics and formation mechanism of the model...

2021-11-11
【Animal Modeling】-Establishment of a nude mouse model of colon cancer liver metastasis

【Animal Modeling】-Establishment of a nude mouse model of colon cancer liver metastasis

How to establish a colon cancer liver metastasis model with high metastasis rate? Is the operation simple? Reliable results of experimental studies on the prevention and treatment of colon cancer metastasis?...

2021-11-11
Effects of low-dose ethanol exposure on liver steatosis and damage in adult zebrafish

Effects of low-dose ethanol exposure on liver steatosis and damage in adult zebrafish

Alcoholic liver disease (ALD) patients show a wide range of defects, from simple steatosis to steatohepatitis, fibrosis, cirrhosis and hepatocellular carcinoma...

2021-11-11