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Effects of Wubao Capsule on Th1/Th2, Th17/Treg imbalance and chemokines in alveolar lavage fluid of asthmatic mice

Effects of Wubao Capsule on Th1/Th2, Th17/Treg imbalance and chemokines in alveolar lavage fluid of asthmatic mice

To observe the effect of national medicine Wubao Capsule on Th1/Th2, Th17/TregE, imbalance and chemokines in the alveolar lavage fluid (bronchoalveolavagefluids, BALF) in asthmatic mice induced by ovalbumin (OVA)  ̄1 impact...

2021-11-09
Changes of monoamine transmitter content and neurofactor expression in the brain area of anxious depression model rats

Changes of monoamine transmitter content and neurofactor expression in the brain area of anxious depression model rats

To study the changes in the levels of monoamine transmitters in the hippocampus, amygdala and prefrontal cortex and the expression trends of neurotrophic factors in the brain of an anxiety-induced depression model rat, and explore its possible pathog...

2021-11-09
【Animal Experiment】-Danggui Buxue Decoction on radiation-damaged mice

【Animal Experiment】-Danggui Buxue Decoction on radiation-damaged mice

Observe the protective effect of Danggui Buxue Decoction on mice irradiated with 60C0-γ rays...

2021-11-09
【Animal Modeling】-Optical Nerve Stretch Injury Model

【Animal Modeling】-Optical Nerve Stretch Injury Model

Regeneration method Anesthetized pentobarbital sodium with a body weight of 30 mg/kg was injected intraperitoneally into a guinea pig weighing about 700 g, and the extraocular muscles were cut with an operating microscope, and the corneal ring was cu...

2021-11-09
【Animal Modeling】-DS-1226 improves the depressive behavior of mice caused by chronic sleep disturbance

【Animal Modeling】-DS-1226 improves the depressive behavior of mice caused by chronic sleep disturbance

To study the antidepressant effect of ginsenoside hydrolysate DS-1226 on mice with chronic sleep disorders, and provide scientific basis for the development of antidepressants...

2021-11-09
【Animal Modeling】-Effect of stress duration of plantar electric shock on anxiety-like behavior in rats

【Animal Modeling】-Effect of stress duration of plantar electric shock on anxiety-like behavior in rats

Observe the effect of individual electric shock stress time on elevated cross maze and anxiety-like behaviors in open experiments in rats...

2021-11-09
【Animal Modeling】-The effect of ginseng polysaccharides on behavior and ERK/c-fos pathway of prefrontal cortex in ethanol-induced behavioral sensitization mice

【Animal Modeling】-The effect of ginseng polysaccharides on behavior and ERK/c-fos pathway of prefrontal cortex in ethanol-induced behavioral sensitization mice

To study the effect of ginseng polysaccharides (GSP) on ethanol-induced behavioral sensitization and its possible mechanism...

2021-11-09
【Animal Modeling】-The effect of sodium oxamate on autophagy and apoptosis of cholangiocarcinoma cells

【Animal Modeling】-The effect of sodium oxamate on autophagy and apoptosis of cholangiocarcinoma cells

To observe the effect of lactate dehydrogenase A (LDHA) inhibitor sodium oxalate on autophagy and apoptosis of human cholangiocarcinoma cell line Hucct-1, and to preliminarily explore its related mechanisms...

2021-11-06
[Animal Modeling]-Effect of Maiqi Jiangtang Pills on blood sugar of ob/ob mice

[Animal Modeling]-Effect of Maiqi Jiangtang Pills on blood sugar of ob/ob mice

How to study the effect of Maiqi Jiangtang Pills on blood glucose levels in ob/ob mice?...

2021-11-06
【Animal Modeling】-How to correctly prepare an osteoporotic tree shrew model by ovariectomized method?

【Animal Modeling】-How to correctly prepare an osteoporotic tree shrew model by ovariectomized method?

Reproduction of postmenopausal osteoporotic tree shrew model with surgical bilateral ovarian castration...

2021-11-06
【Animal Modeling】-The secretion of melatonin from the lungs helps to resist the new coronavirus infection

【Animal Modeling】-The secretion of melatonin from the lungs helps to resist the new coronavirus infection

In a recent study, researchers at the University of São Paulo (USP) in Brazil found that melatonin synthesized in the lungs may act as a barrier to SARS-CoV-2 and prevent the expression of genes that contribute to virus invasion...

2021-11-06
【Animal Modeling】-Animal Model of Acute Gastric Ulcer Induced by Chemicals

【Animal Modeling】-Animal Model of Acute Gastric Ulcer Induced by Chemicals

Reproduction method: adult experimental mice, fast for 48 hours, absolute ethanol (5 ml/kg body weight) or acetylsalicylic acid (200 mg/kg body weight), or 0.6 mol/L hydrochloric acid (10 ml/kg) for 1 hour Later, the animals were sacrificed by cervic...

2021-11-06
Changes of Blood Indexes in Long-term Toxicity Tests of Niaotong Kak Naiqi Tablets

Changes of Blood Indexes in Long-term Toxicity Tests of Niaotong Kak Naiqi Tablets

To explore the changes of hematological indexes in the rat long-term toxicity test of Uotongkaknaiqi tablets...

2021-11-06
【Disease animal model】-animal model of rat cerebral palsy

【Disease animal model】-animal model of rat cerebral palsy

Newborn rats underwent ligation of the right common carotid artery under awake and local anesthesia. The animals were placed in a constant temperature airtight glass container and vented with a mixed gas of 8% oxygen + 92% nitrogen. After 2 hours, th...

2021-11-06
[Animal experiment]-Vaccine targeting RBP-4 reduces blood sugar in type 2 diabetic mice

[Animal experiment]-Vaccine targeting RBP-4 reduces blood sugar in type 2 diabetic mice

Explore the effectiveness and feasibility of vaccine immune intervention with human-derived RBP-4 as the target of insulin resistance, and provide basic research data for the further development of new therapies for type 2 diabetes...

2021-11-06
[Animal Modeling]-Gene Cloning and Preliminary Function Study of Junction Adhesion Molecule A

[Animal Modeling]-Gene Cloning and Preliminary Function Study of Junction Adhesion Molecule A

To obtain the full-length coding sequence of the conjugative adhesion molecule A (AJAM-A), analyze its molecular characteristics, and use JAM as the receptor for Leovirus that invades the primary lung cells of the conjugative adhesion molecule...

2021-11-06