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【Animal modeling】-Isolation and identification of mouse CD4+ T cell exosomes

【Animal modeling】-Isolation and identification of mouse CD4+ T cell exosomes

To investigate whether CD4+ T cells have the ability to secrete exosomes, and the possibility of CD4+ T cell exosomes participating in inflammation and tumor immune processes...

2022-09-24
【Animal modeling】Effect of -17βestradiol on propofol-induced apoptosis of cortical neurons

【Animal modeling】Effect of -17βestradiol on propofol-induced apoptosis of cortical neurons

To investigate the effect and mechanism of 17β-estradiol on the apoptosis of primary cultured cortical neurons induced by propofol...

2022-09-24
【Animal modeling】-Effect of sesame oil on the expression of insulin sensitivity-related genes in skeletal muscle of insulin-resistant rats

【Animal modeling】-Effect of sesame oil on the expression of insulin sensitivity-related genes in skeletal muscle of insulin-resistant rats

To investigate the effect of a high-fat diet of thulia oil rich in n-3 polyunsaturated fatty acids on insulin sensitivity and the expression of related genes in insulin-resistant rats...

2022-09-24
【Animal modeling】-Exploration of nutritional intervention measures during long-distance transportation of tree shrew

【Animal modeling】-Exploration of nutritional intervention measures during long-distance transportation of tree shrew

To explore appropriate nutritional intervention methods to reduce the adverse effects of stress response caused by long-distance transportation on experimental tree shrew...

2022-09-24
【Animal Modeling】-Preliminary Study on the Toxicity of Different Extracts of Psoralen to Rats

【Animal Modeling】-Preliminary Study on the Toxicity of Different Extracts of Psoralen to Rats

To study the toxicity of oral administration of different extracts of Psoralen to rats, and provide a safety basis for its clinical application...

2022-09-24
【Animal Modeling】-The neuroprotective effect and mechanism of Dendrobium officinale on MPTP-induced PD mice

【Animal Modeling】-The neuroprotective effect and mechanism of Dendrobium officinale on MPTP-induced PD mice

To investigate the neuroprotective effect of Dendrobium officinale extract in a mouse model of Parkinson\'s disease induced by 1-methylv-4-phenyl-1,2,3,6-tetrahydropyridine...

2022-09-24
【Animal modeling】-Comparative study on the pharmacokinetics of Eucommia ulmoides extract in normal rats and SHR models after multiple administrations

【Animal modeling】-Comparative study on the pharmacokinetics of Eucommia ulmoides extract in normal rats and SHR models after multiple administrations

To study the effect of 7 active components of pinoresinol diglucoside, geniposide chlorogenic acid, protocatechuic acid, neochlorogenic acid, cryptochlorogenic acid and pinoresinol monoglucoside after repeated administration of Eucommia ulmoides extr...

2022-09-24
【Animal modeling】-The improvement effect of Baixiangdan capsule on premenstrual anxiety disorder caused by ovariectomy in rats

【Animal modeling】-The improvement effect of Baixiangdan capsule on premenstrual anxiety disorder caused by ovariectomy in rats

To compare traditional Chinese medicine Baixiangdan Capsules (BXD), serotonin 3 receptor (5-HT3R) specific agonists and their antagonists, cannabinoid receptor 1 (CB1R) specific agonists and their antagonists through a series of behavioral tests. Int...

2022-09-24
【Animal modeling】-Protective effect of amygdalin on necrotizing enterocolitis in neonatal rats

【Animal modeling】-Protective effect of amygdalin on necrotizing enterocolitis in neonatal rats

To analyze the protective effect of amygdalin on necrotizing enterocolitis (NEC) in neonatal rats...

2022-09-24
【Animal Modeling】-Anesthesia effect of Shutai and Lumianning compound doses on Bama miniature pigs

【Animal Modeling】-Anesthesia effect of Shutai and Lumianning compound doses on Bama miniature pigs

To study the anesthesia effect of Shutai and Lu Mianning compound anesthesia on Bama miniature pigs, and to preliminarily observe the effect of anesthesia on the physiological indexes of miniature pigs...

2022-09-24
【Animal modeling】-Effect of low expression of lipoic acid synthase on antioxidant capacity in mice

【Animal modeling】-Effect of low expression of lipoic acid synthase on antioxidant capacity in mice

To establish a genetically modified mouse with low expression of lipoic acid synthase gene, and to test its antioxidant capacity...

2022-09-24
【Animal Modeling】-Analysis of the effects of different hypoxia exposure modes on differential gene expression of rat tibialis anterior muscle based on RNA sequencing

【Animal Modeling】-Analysis of the effects of different hypoxia exposure modes on differential gene expression of rat tibialis anterior muscle based on RNA sequencing

To screen the differentially expressed genes and their related pathways in rat tibialis anterior muscle from chronic intermittent hypoxia exposure and acute hypoxia exposure...

2022-09-24
【Animal modeling】-Effect of Jiayankangtai granules on immune-related cytokines in autoimmune thyroiditis rats

【Animal modeling】-Effect of Jiayankangtai granules on immune-related cytokines in autoimmune thyroiditis rats

To detect the effect of Jiayankangtai granules on immune-related cytokines in autoimmune thyroiditis rats, and to explore the mechanism of Jiayankangtai granules in improving autoimmune thyroiditis...

2022-09-24
【Animal Modeling】-Effect and mechanism of Bushen Yiqi Huayu Granule on the formation of blood vessels in ovariectomized osteoporosis model rats

【Animal Modeling】-Effect and mechanism of Bushen Yiqi Huayu Granule on the formation of blood vessels in ovariectomized osteoporosis model rats

To explore the effect of Bushen Yiqi Huayu Granule on angiogenesis in osteoporosis rats based on TLRs/NF-κB signaling pathway...

2022-09-24
【Animal modeling】-Kallikrein alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

【Animal modeling】-Kallikrein alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

To investigate the effect of pancreatic kininogenase on myocardial injury, oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury...

2022-09-24
【Animal modeling】-Based on autophagy to investigate the effect of fentanyl combined with propofol on cardiac ischemia-reperfusion injury in rats

【Animal modeling】-Based on autophagy to investigate the effect of fentanyl combined with propofol on cardiac ischemia-reperfusion injury in rats

To investigate the effect of fentanyl combined with propofol on cardiac ischemia-reperfusion injury in rats based on autophagy...

2022-09-24