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【Animal modeling】-Observation of multimodal molecular functional imaging of female rhesus monkey kidneys at different ages

【Animal modeling】-Observation of multimodal molecular functional imaging of female rhesus monkey kidneys at different ages

To observe various imaging indexes such as GFR, ADC, SUV, CT value of female rhesus monkey kidney in different age groups, and to explore the effect of age on various imaging quantitative indexes of female rhesus monkey kidney...

2022-09-22
[Animal modeling]-The unique metabolic activation of adipose tissue in obese patients promotes inflammation

[Animal modeling]-The unique metabolic activation of adipose tissue in obese patients promotes inflammation

Macrophages accumulate in adipose tissue, trigger chronic low-grade inflammation, and promote the development of systemic insulin resistance...

2022-09-22
【Animal Modeling】-Effect of endometriosis on the fertility of mice

【Animal Modeling】-Effect of endometriosis on the fertility of mice

To establish a mouse model of endometriosis, and to observe the effect of endometriosis on the pregnancy ability of the model mice...

2022-09-21
USC Scientists Use TRAP Technology to Capture Early Signs of Acute Kidney Injury in Mice

USC Scientists Use TRAP Technology to Capture Early Signs of Acute Kidney Injury in Mice

Recently, USC stem cell scientists have successfully set up a mouse that captures acute kidney injury disease signals, using this TRAP mouse to capture early signs of kidney failure, the description was published in the Journal of Clinical Investigat...

2022-09-21
【Animal Modeling】-Analysis of basic physiological and biochemical indicators of male and female FMMU albino guinea pigs

【Animal Modeling】-Analysis of basic physiological and biochemical indicators of male and female FMMU albino guinea pigs

To measure and compare the blood indexes, heart rate, common carotid arterial pressure, ventricular pressure and organ parameters of female and male common-grade FMMU albino guinea pigs...

2022-09-21
【Animal Modeling】-Animal Model of Sclerosing Glomerulonephropathy

【Animal Modeling】-Animal Model of Sclerosing Glomerulonephropathy

Sclerosing glomerulonephritis is the end stage of many types of glomerulonephritis, rather than an independent pathological type of glomerulonephritis. The pathological changes are characterized by extensive glomerulosclerosis, renal tubular atrophy...

2022-09-21
【Animal Model】-Effect of X-ray whole body irradiation on the function of hematopoietic immune system in KKAy mice with type 2 diabetes

【Animal Model】-Effect of X-ray whole body irradiation on the function of hematopoietic immune system in KKAy mice with type 2 diabetes

To observe the damage effect of X-ray whole body irradiation on the function of hematopoietic immune system in KKAy mice, a model of type 2 diabetes mellitus, and compare it with control C57 mice...

2022-09-21
【Animal Modeling】-Zucker Diabetic Obesity Rats Cerebrovascular Disease Characteristics and Pathogenesis Study

【Animal Modeling】-Zucker Diabetic Obesity Rats Cerebrovascular Disease Characteristics and Pathogenesis Study

To observe the pathological characteristics of cerebrovascular disease in Zucker diabetic obese (ZDF) rats, and to preliminarily explore its pathogenesis, so as to provide experimental basis and theoretical basis for the application of ZDF rats...

2022-09-21
【Animal Modeling】-Effect of Bushen Yangxue Recipe on Anti-Müllerian Hormone in Rats with Premature Ovarian Failure

【Animal Modeling】-Effect of Bushen Yangxue Recipe on Anti-Müllerian Hormone in Rats with Premature Ovarian Failure

To establish a rat model of premature ovarian failure induced by Tripterygium wilfordii polyglycosides, and to study the effect of Bushen Yangxue Recipe on anti-mullerian in rats with premature ovarian failure...

2022-09-21
【Animal modeling】-MMP12 deletion causes changes in macrophages in blood and white fat in mice

【Animal modeling】-MMP12 deletion causes changes in macrophages in blood and white fat in mice

MMP12, also known as macrophage elastase, can almost decompose various extracellular matrix components and vascular components, and is related to the recruitment of monocytes. It was also found that MMP12 is involved in the invasion and metastasis of...

2022-09-21
【Animal Modeling】-Isolation, Culture and Identification of Mouse Lung Mesenchymal Stem Cells

【Animal Modeling】-Isolation, Culture and Identification of Mouse Lung Mesenchymal Stem Cells

To establish a stable technique for the isolation, culture and identification of mouse lung mesenchymal stem cells, and to study the mechanism of lung tissue repair and regeneration using mouse lung mesenchymal stem cells...

2022-09-21
【Animal modeling】-The expression changes and effects of BDNF and its receptor TrkB in hypoxia-preconditioned mice

【Animal modeling】-The expression changes and effects of BDNF and its receptor TrkB in hypoxia-preconditioned mice

To explore the expression changes and effects of BDNF, TrkB receptor and BDNF/TrkB signaling pathway in acute hypoxia and hypoxia preconditioning mice, to further improve the molecular mechanism of hypoxia preconditioning neuroprotection, and to prov...

2022-09-21
【Animal Modeling】-Adenine-induced abnormal bone and mineral metabolism in a rat model of chronic kidney disease

【Animal Modeling】-Adenine-induced abnormal bone and mineral metabolism in a rat model of chronic kidney disease

To observe the biochemical markers of mineral metabolism in adenine-induced chronic kidney disease rat model? The characteristics of vascular calcification and renal bone disease?...

2022-09-20
【Animal Modeling】-Comparative study of hepatotoxicity between matrine and oxymatrine in vitro and in vivo models

【Animal Modeling】-Comparative study of hepatotoxicity between matrine and oxymatrine in vitro and in vivo models

To compare the hepatotoxicity of matrine and oxymatrine, to explore the severity and characteristics of their toxicity, and to preliminarily clarify the toxicity mechanism?...

2022-09-20
【Animal Modeling】-Discussion on the feasibility of acupuncture treatment of chronic myocardial ischemia miniature pig model series

【Animal Modeling】-Discussion on the feasibility of acupuncture treatment of chronic myocardial ischemia miniature pig model series

To investigate the feasibility of a series of methods for treating chronic myocardial ischemia in miniature pigs with an Ameroid constriction ring placed in the left anterior descending artery with embedded needles...

2022-09-20
【Animal Modeling】-Establishment of a mouse model of chronic renal insufficiency induced by repeated injection of cisplatin

【Animal Modeling】-Establishment of a mouse model of chronic renal insufficiency induced by repeated injection of cisplatin

To construct a C57BL/6 mouse model of chronic kidney disease, and to explore the changes of its tubular injury indexes and interstitial fibrosis with the dose of cisplatin, so as to provide an animal experimental basis for studying the progression fr...

2022-09-20