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【Animal modeling】Effect of -17βestradiol on propofol-induced apoptosis of cortical neurons

【Animal modeling】Effect of -17βestradiol on propofol-induced apoptosis of cortical neurons

To investigate the effect and mechanism of 17β-estradiol on the apoptosis of primary cultured cortical neurons induced by propofol...

2022-09-19
【Animal modeling】-Effect of curcumin on the expression of hepatic 11β-HSD1 and insulin resistance in rats with non-alcoholic fatty liver disease

【Animal modeling】-Effect of curcumin on the expression of hepatic 11β-HSD1 and insulin resistance in rats with non-alcoholic fatty liver disease

To observe the effect of curcumin on the expression of hepatic 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) and insulin resistance in rats with nonalcoholic fatty liver disease (NAFLD)...

2022-09-19
【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

To observe the effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats...

2022-09-19
【Animal Modeling】-Hydrogen peroxide-induced changes in isolated rat uterine ligament fibroblasts

【Animal Modeling】-Hydrogen peroxide-induced changes in isolated rat uterine ligament fibroblasts

To investigate the effect and possible mechanism of oxidative stress on the proliferation, apoptosis, collagen synthesis and inflammatory factor expression of uterine ligament fibroblasts...

2022-09-19
【Animal Modeling】-Study reveals that chlorothalonil affects the survival and gut microbial diversity of bee larvae

【Animal Modeling】-Study reveals that chlorothalonil affects the survival and gut microbial diversity of bee larvae

Recently, a research team from the Institute of Honey Bee Research, Chinese Academy of Agricultural Sciences found that high exposure doses of the fungicide chlorothalonil reduced the survival rate of indoor artificially reared bee larvae, changed th...

2022-09-19
【Animal Modeling】-Systematic Evaluation of Animal Models of Inflammation Induced by Atmospheric Fine Particulate Matter

【Animal Modeling】-Systematic Evaluation of Animal Models of Inflammation Induced by Atmospheric Fine Particulate Matter

To explore the pathogenic mechanism of air pollution on animals, and to construct an animal model of air pollution-induced inflammation by non-invasive tracheal instillation of PM2.5 particle suspension in BALB/c mice...

2022-09-16
【Animal modeling】-Establishment of cynomolgus monkey muscle atrophy model

【Animal modeling】-Establishment of cynomolgus monkey muscle atrophy model

To establish an animal model of cynomolgus monkey muscle atrophy by restricting lower extremity activities, and to establish a method for evaluating the model?...

2022-09-16
【Animal modeling】-Establishment of a rat model of uterine fibroids-bearing transplanted tumor

【Animal modeling】-Establishment of a rat model of uterine fibroids-bearing transplanted tumor

To establish a rat model of uterine fibroids-bearing tissue transplanted by tissue transplantation in immunosuppressive rats, and to provide a new animal model for the study of uterine fibroids...

2022-09-16
【Animal modeling】-Establishment of a rat model of lumbar ventral nerve root traction

【Animal modeling】-Establishment of a rat model of lumbar ventral nerve root traction

To study the pathogenic mechanism and drug development of amyotrophic lateral sclerosis, establish a rat model of pulling the fourth lumbar ventral nerve root, and use brain-derived neurotrophic factor as a positive drug to verify the effectiveness o...

2022-09-16
【Animal Modeling】-Experimental Study on Rat Model of Hypertension Complicated with Hyperlipidemia

【Animal Modeling】-Experimental Study on Rat Model of Hypertension Complicated with Hyperlipidemia

To construct a rat model of hypertension complicated with hyperlipidemia by feeding spontaneously hypertensive rats (SHR) with high-fat diet, and to evaluate the damage of the heart and kidney, so as to provide a useful reference for the treatment of...

2022-09-16
【Animal Modeling】-Effect of solitary rearing on the behavior of rat model of post-traumatic stress disorder established by a single prolonged stress

【Animal Modeling】-Effect of solitary rearing on the behavior of rat model of post-traumatic stress disorder established by a single prolonged stress

To establish a model of post-traumatic stress disorder by single prolonged stress, and to observe the effect of solitary rearing on SPS model rats...

2022-09-16
【Animal Modeling】-Construction of C57bl/6j Mouse Melanoma Lung Metastasis Model

【Animal Modeling】-Construction of C57bl/6j Mouse Melanoma Lung Metastasis Model

To investigate the influencing factors of establishing a C57BL/6J mouse melanoma model with lung metastasis, including tumor inoculation method, cell inoculation number and tumorigenic cycle...

2022-09-16
【Animal modeling】-Urinary metabolome study on the rat model of abnormal black gallbladder syndrome in Uyghur medicine

【Animal modeling】-Urinary metabolome study on the rat model of abnormal black gallbladder syndrome in Uyghur medicine

To evaluate and discuss the biological markers of the rat model of abnormal black gallbladder syndrome in Uyghur medicine by combining the observation of external characteristics with the study of urine metabolome...

2022-09-16
【Animal modeling】-Establishment and mechanism of BALB/c mouse model of total hysterectomy

【Animal modeling】-Establishment and mechanism of BALB/c mouse model of total hysterectomy

To establish an experimental animal model of total hysterectomy in BALB/c mice, and to explore and analyze the characteristics and formation mechanism of the model...

2022-09-16
【Animal modeling】-Study on coagulation function of rat sepsis model

【Animal modeling】-Study on coagulation function of rat sepsis model

To investigate the changes of coagulation function in a rat model of sepsis induced by cecal ligation and puncture...

2022-09-16
【Animal Modeling】-Technical method for the creation of renal ischemia-reperfusion injury model by dorsal retroperitoneal double renal pedicle clipping

【Animal Modeling】-Technical method for the creation of renal ischemia-reperfusion injury model by dorsal retroperitoneal double renal pedicle clipping

To explore a method for making a rat model of renal ischemia-reperfusion injury with less injury, simple operation and stable effect...

2022-09-16