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【Animal modeling】-Establishment of acute and chronic hyperuricemia models

【Animal modeling】-Establishment of acute and chronic hyperuricemia models

To establish acute mouse and chronic rat hyperuricemia models, and use positive drugs to verify the curability of the two models, so as to provide model tools for the development of anti-hyperuric acid drugs...

2022-09-13
【Animal Modeling】-An improved method for establishing myocardial ischemia-reperfusion injury model in rats

【Animal Modeling】-An improved method for establishing myocardial ischemia-reperfusion injury model in rats

To comprehensively evaluate the improved method for establishing myocardial ischemia-reperfusion injury model in rats...

2022-09-13
【Animal Modeling】-Gene-modified SLE mouse model

【Animal Modeling】-Gene-modified SLE mouse model

Transgenic mouse model B6.Cg-Tg (Actb-TNFRSF6B) 754Jwu/J, gene knock-in mouse model 129S6.129X1 (B6)-Ptprctm1Weis / and many other types of transgenic mouse models for studying autoimmune diseases Have. J and B6.129X1-Ptprctm1Weis/J, gene knockout mo...

2022-09-13
【Animal modeling】-Protective effect of stilbene glycosides inhibiting NADPH oxidase on cerebral ischemia/reperfusion injury in mice

【Animal modeling】-Protective effect of stilbene glycosides inhibiting NADPH oxidase on cerebral ischemia/reperfusion injury in mice

To investigate the protective effect of stilbene glycoside (TSG) inhibiting NADPH oxidase on cerebral ischemia-reperfusion (I/R) injury in mice...

2022-09-13
【Animal modeling】-Effect of Fkbp51 knockout on alternative splicing of mouse liver transcriptome

【Animal modeling】-Effect of Fkbp51 knockout on alternative splicing of mouse liver transcriptome

To study the effect of Fkbp51 knockout on gene alternative splicing in liver tissue by analyzing the expression profiles of Fkbp51 gene knockout and wild-type mice livers...

2022-09-12
【Animal modeling】-Establishment of a porcine cornea test for acute eye irritation of a disinfectant

【Animal modeling】-Establishment of a porcine cornea test for acute eye irritation of a disinfectant

To establish an in vitro method for the detection of acute eye irritation of disinfected products using porcine cornea...

2022-09-12
【Animal modeling】-A modeling method of postnatal mouse restraint stress model and the production of restraint device

【Animal modeling】-A modeling method of postnatal mouse restraint stress model and the production of restraint device

To create a self-made restraint device for mice, and to establish a postnatal mouse restraint stress model for related stress experiments...

2022-09-09
【Animal Modeling】-Establishment and Evaluation of a Mouse Model of Diabetic Lower Limb Ulcer

【Animal Modeling】-Establishment and Evaluation of a Mouse Model of Diabetic Lower Limb Ulcer

To establish and evaluate a mouse model of diabetic lower extremity ulcer, reveal the changes of blood flow and pathophysiology in the operated limb of diabetic lower extremity ulcer mice, and explore its pathogenesis, so as to provide a basis and re...

2022-09-09
【Animal Modeling】-Establishment and rapid detection of an animal model of immunocompromised mice

【Animal Modeling】-Establishment and rapid detection of an animal model of immunocompromised mice

To quickly establish an animal model of KM mice with low immunity, and use a simple and rapid method to identify the establishment of the animal model...

2022-09-09
【Animal Modeling】-Analysis of the application of asthma animal model based on data mining

【Animal Modeling】-Analysis of the application of asthma animal model based on data mining

To analyze the modeling elements of asthma animal models, and to provide methodological reference for improving the success rate of modeling and evaluating the tested drugs effectively...

2022-09-09
【Animal modeling】-Establishment and evaluation of a rat model of chronic obstructive pulmonary disease

【Animal modeling】-Establishment and evaluation of a rat model of chronic obstructive pulmonary disease

To construct a rat model of chronic obstructive pulmonary disease by smoking method, protease instillation and a combination of the two methods...

2022-09-09
【Animal modeling】-Construction of myocardial iron overload rabbit model and study of iron deposition law

【Animal modeling】-Construction of myocardial iron overload rabbit model and study of iron deposition law

To investigate the method of making an animal model of myocardial iron deposition and the relationship between the iron deposition in the heart and liver...

2022-09-09
【Animal Modeling】-Experimental Observation on Evaluation Points of Blood Glucose Intervention in Mice Model of Type 2 Diabetes

【Animal Modeling】-Experimental Observation on Evaluation Points of Blood Glucose Intervention in Mice Model of Type 2 Diabetes

To observe the changes of blood glucose in a mouse model of type 2 diabetes mellitus, and to explore the feasibility of 2 h postprandial blood glucose as an evaluation point for blood glucose intervention...

2022-09-09
【Animal Modeling】-Observation on Induced Anxiety and Depression-like Emotional Behavior in Chronic Inflammatory Pain Model Rats

【Animal Modeling】-Observation on Induced Anxiety and Depression-like Emotional Behavior in Chronic Inflammatory Pain Model Rats

To dynamically observe the changes of pain emotion in chronic inflammatory pain model rats induced by complete Freund\'s adjuvant (CFA), and to explore the time differences of anxiety and depression in chronic inflammatory pain model rats...

2022-09-09
【Animal Modeling】-In vitro and animal models for SARS-CoV-2 research

【Animal Modeling】-In vitro and animal models for SARS-CoV-2 research

In December 2019, China confirmed pneumonia of unknown etiology. The Chinese Center for Disease Control and Prevention (CCDC) has identified a novel coronavirus infection as the cause of the pneumonia...

2022-09-09
【Animal modeling】-Effect of postconditioning with dezocine on acute lung injury induced by intestinal ischemia-reperfusion in rats

【Animal modeling】-Effect of postconditioning with dezocine on acute lung injury induced by intestinal ischemia-reperfusion in rats

To investigate the effect and possible mechanism of dezocine postconditioning on acute lung injury induced by intestinal ischemia-reperfusion in rats...

2022-09-09