【Animal Modeling】-Hydrogen-rich liquid attenuates cerebral ischemia-reperfusion injury in rats through PI3K pathway

To investigate the effect of hydrogen-rich solution on the apoptosis of hippocampal neurons and the expression of PI3K/Akt/FoxO1 signaling pathway induced by cerebral ischemia-reperfusion in rats...

2022-03-30

【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

This paper reports an improved method for the isolation of rat thoracic aortic vascular smooth muscle cells based on compound enzymatic digestion...

2022-03-30

【Animal Modeling】-DB11/T828.3-2011 Chromosome 12 Marker Screening and Applicability Evaluation Research

To screen the vacant chromosome 12 markers in the local standard of Beijing miniature pig genetic quality control DB11/T828.3-2011, and to analyze the applicability of landmarks by comparing the genetic evaluation of different markers in the same pop...

2022-03-30

【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

To investigate the effects of different administration routes and doses of cyclophosphamide on the embryos and fetuses of pregnant rabbits, so as to determine the best administration method for inducing fetal malformation in rabbits...

2022-03-30

【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

To observe the protective effect of GDF11 on myocardial injury in C57BL/6J mice with type Ⅱ diabetes mellitus and the changes of myocardial apoptosis...

2022-03-30

【Animal modeling】-Micro-CT observation of the effect of recombinant human parathyroid hormone on fracture healing in 2-month-old male rats

To investigate the effect of recombinant human parathyroid hormone (rhPTH) on fracture healing in 2-month-old male rats using Micro-CT...

2022-03-30

【Animal Modeling】-Proliferation of umbilical cord mesenchymal stem cells on dairy bovine mammary epithelial cells under serum-free co-culture conditions

To investigate the proliferation effect of umbilical cord mesenchymal stem cells on dairy bovine mammary epithelial cells under serum-free co-culture conditions...

2022-03-30

【Animal Modeling】-Comparison of Ulcer Wound Healing in Two Type 2 Diabetic Mice

To compare the healing characteristics of ulcer wounds in C57BL/6J-db/db and STZ-induced C57BL/6J mice with type 2 diabetes mellitus commonly used, and to conduct relevant animal experiments for the application of a stable diabetic mouse ulcer model ...

2022-03-30

【Animal modeling】-Effect of rhubarb root extract on the morphology of tissues and organs in mice with experimental psoriasis

To investigate the effect of rhubarb root extract on the morphology of tissues and organs in experimental psoriasis model mice...

2022-03-30

【Animal modeling】The effect of -1α,25(OH)2D3 on the expression of lubricin in rat articular chondrocytes

To investigate the effect of 1α,25(OH)2D3 on the synthesis and secretion of lubricin in chondrocytes at the cellular level...

2022-03-30

【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

To clarify the differentiation of macrophages derived from THP-1 cells induced by PMA alone by flow cytometry...

2022-03-30

【Animal Modeling】-Effects of Vanadium Exposure on Inflammatory Response and Migration of Rat Microglia

To observe the effects of sodium metavanadate (NaVO3·2H2O) exposure on the inflammatory response and migration of microglia, and to explore the related mechanism of vanadium neurotoxicity...

2022-03-30

【Animal Modeling】-Effects of intermedia and adrenomedullin on cerebral microcirculation in rats with focal cerebral ischemia

To investigate the effects of intermedin and adrenomedullin on cerebral microcirculation in rats with focal cerebral ischemia...

2022-03-29

【Animal modeling】-Effect of Tempol on NF-κB signaling pathway in myocardial hypertrophy rats

To investigate the effect of 2, 2, 6, 6-tetramethyl-4-piperidinol (temPol) on NF-κB signaling pathway in rat cardiac hypertrophy?...

2022-03-29

【Animal modeling】-Comparison of dopamine content in the lateral geniculate body of guinea pigs with flash-induced myopia and form deprivation myopia

To observe the changes of dopamine (DA) content in the lateral geniculate body in guinea pig models of flicker-induced myopia and form deprivation myopia, and to conduct a comparative analysis, and to preliminarily explore the central pathogenesis of...

2022-03-29

【Animal Modeling】-Effect of high-fat diet feeding time on type 2 diabetic nephropathy rat model

To explore the effects of different high-fat diet feeding time on blood glucose, insulin resistance index (HOMA-IR) and urinary albumin excretion rate (UAER) in induced type 2 diabetic nephropathy (DN) rat model...

2022-03-29