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【Animal modeling】-The effect of TRPV4 receptor on angiotensin II-induced renal damage in mice

【Animal modeling】-The effect of TRPV4 receptor on angiotensin II-induced renal damage in mice

To investigate the role of TRPV4 receptor in angiotensin II-induced renal damage by using transient receptor potential vanilloid 4 knockout (TRPV4 - / - ) mice...

2022-03-29
【Animal modeling】-Effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

【Animal modeling】-Effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

To investigate the effect of artificial recombinant botulinum toxin type A heavy chain (BoNT/A heavy chain) on the expression of local growth-related proteins in rats with spinal cord injury in vivo, and to provide a basis for elucidating the mechani...

2022-03-29
【Animal modeling】-Effect of vitamin D deficiency on the pathogenesis of spontaneously diabetic rats

【Animal modeling】-Effect of vitamin D deficiency on the pathogenesis of spontaneously diabetic rats

To investigate the effect of vitamin D (VD) deficiency on the pathogenesis of spontaneous diabetic rats...

2022-03-29
【Animal Modeling】-Injury effect of high-frequency electromagnetic radiation on emotion-cognitive behavior in mice

【Animal Modeling】-Injury effect of high-frequency electromagnetic radiation on emotion-cognitive behavior in mice

To explore the establishment of a model of mouse emotional-cognitive behavioral damage caused by high-frequency electromagnetic radiation, and to provide an experimental basis for the study of radiation damage mechanism and protection...

2022-03-29
【Animal Modeling】-Comparison of Transparency of Six Optical Transparency Methods in Rat Brain Tissue Blocks

【Animal Modeling】-Comparison of Transparency of Six Optical Transparency Methods in Rat Brain Tissue Blocks

To compare the transparent effects of six optical clearing methods on rat brain tissue blocks...

2022-03-29
【Animal Modeling】-Using TaqMan probe fluorescence quantitative PCR technology to identify the genotype of Leprdb/+ mice offspring

【Animal Modeling】-Using TaqMan probe fluorescence quantitative PCR technology to identify the genotype of Leprdb/+ mice offspring

To establish an efficient method for genotyping the offspring of Leprdb/ + mice using TaqMan probe fluorescence quantitative PCR technology...

2022-03-29
【Animal modeling】-Blocking macrophage-mediated PD1/PD-L1 pathway inhibits tuberculosis recurrence in mice

【Animal modeling】-Blocking macrophage-mediated PD1/PD-L1 pathway inhibits tuberculosis recurrence in mice

To block the macrophage-mediated PD1/PD-L1 pathway with functional PD-L1 monoclonal antibody, and to study its immune intervention effect and mechanism on the relapse of tuberculosis in mice after treatment...

2022-03-29
【Animal Modeling】-Experimental Study of Riboflavin and Ultraviolet Irradiation in Preventing Progressive Myopia in Guinea Pigs

【Animal Modeling】-Experimental Study of Riboflavin and Ultraviolet Irradiation in Preventing Progressive Myopia in Guinea Pigs

Myopia, especially high myopia, is associated with major eye diseases that ultimately lead to blindness, such as exudative myopic macular degeneration, rhegmatogenous retinal detachment, myopic retinopathy, and glaucoma. The mechanism of myopia is no...

2022-03-28
【Animal Modeling】-Effect of 4-week ladder-climbing resistance training on hypoxia-induced skeletal muscle atrophy in rats

【Animal Modeling】-Effect of 4-week ladder-climbing resistance training on hypoxia-induced skeletal muscle atrophy in rats

To explore the effect of resistance training against hypoxia-induced skeletal muscle atrophy, and to provide a theoretical basis for solving the problem of skeletal muscle loss in athletes during altitude training...

2022-03-28
【Animal modeling】-The protective effect of mild hypothermia on radiation-induced lung injury in rats

【Animal modeling】-The protective effect of mild hypothermia on radiation-induced lung injury in rats

To investigate the protective effect of mild hypothermia on radiation-induced lung injury, and to compare the protective effect with amifostine, a commonly used clinical anti-radiation drug...

2022-03-28
【Animal modeling】-The effect of Dendrobium officinale polysaccharide on chronic atrophic gastritis in rats and its molecular mechanism

【Animal modeling】-The effect of Dendrobium officinale polysaccharide on chronic atrophic gastritis in rats and its molecular mechanism

To investigate the effect and molecular mechanism of Dendrobium officinale polysaccharide on nitrosoguanidine-induced chronic atrophic gastritis in rats...

2022-03-28
【Animal modeling】-Effect of emodin on fat browning in ApoE knockout mice

【Animal modeling】-Effect of emodin on fat browning in ApoE knockout mice

To observe the effect of emodin on fat browning in apolipoprotein E knockout mice, so as to explore its mechanism of improving blood stasis states such as hyperlipidemia...

2022-03-28
【Animal Modeling】-Effect of Xingnao Zaizao Capsule on memory impairment induced by formaldehyde in mice

【Animal Modeling】-Effect of Xingnao Zaizao Capsule on memory impairment induced by formaldehyde in mice

To investigate the effect of Xingnao Zaizao capsule on the memory impairment induced by formaldehyde in mice and its mechanism...

2022-03-28
【Animal modeling】-Effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats

【Animal modeling】-Effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats

To explore the effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats...

2022-03-28
【Animal modeling】-Effect of perfluorooctane sulfonate on rat embryonic development and placental IGF-1 expression

【Animal modeling】-Effect of perfluorooctane sulfonate on rat embryonic development and placental IGF-1 expression

To investigate the effects of different doses of perfluorooctane sulfonate exposure on embryonic development and placental insulin-like growth factor-1 expression in rats...

2022-03-28
【Animal Modeling】-Therapeutic effect of anti-C5aR antibody combined with allicin on induced inflammatory bowel disease in rats

【Animal Modeling】-Therapeutic effect of anti-C5aR antibody combined with allicin on induced inflammatory bowel disease in rats

To explore the therapeutic effect of anti-complement 5a receptor (C5aR) antibody combined with allicin on inflammatory bowel disease (IBD) in rats...

2022-03-25