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【Animal Modeling】-Prophylactic use of trigonelline reduces symptoms in a rat model of pregnancy-induced hypertension and protects fetal growth and vascular endothelial function

【Animal Modeling】-Prophylactic use of trigonelline reduces symptoms in a rat model of pregnancy-induced hypertension and protects fetal growth and vascular endothelial function

To determine the therapeutic effect of trigonelline in early pregnancy in rats with PE induced by the nitric oxide synthase antagonist N-nitro-1-arginine methyl ester (LNAME)...

2022-03-23
[Animal modeling]-Inhibitory effect of atrial natriuretic peptide on the growth of transplanted melanoma in gene knockout mice

[Animal modeling]-Inhibitory effect of atrial natriuretic peptide on the growth of transplanted melanoma in gene knockout mice

How to study the effect of atrial natriuretic peptide on the growth of melanoma...

2022-03-23
【Animal Modeling】-Effect of geranin on meconium-induced acute lung injury in neonatal rats and its mechanism

【Animal Modeling】-Effect of geranin on meconium-induced acute lung injury in neonatal rats and its mechanism

To investigate the effect of geranin on meconium-induced acute lung injury in neonatal rats and its molecular mechanism...

2022-03-23
【Animal modeling】-Changes of IL-6, SOD and MDA in the lung tissue of rats with acute pulmonary edema

【Animal modeling】-Changes of IL-6, SOD and MDA in the lung tissue of rats with acute pulmonary edema

To investigate the changes and significance of malondialdehyde, superoxide dismutase and interleukin-6 in lung tissue of acute hypoxia-induced acute pulmonary edema in rats...

2022-03-23
【Animal modeling】-Astragalus polysaccharide regulates Sirt1/FoxO1 pathway and inhibits autophagy in granulosa cells of rats with polycystic ovary syndrome

【Animal modeling】-Astragalus polysaccharide regulates Sirt1/FoxO1 pathway and inhibits autophagy in granulosa cells of rats with polycystic ovary syndrome

To investigate the effect of astragalus polysaccharide (APS) regulating the silent information regulator 1/forkhead transcription factor O1 ( Sirt1 / FoxO1) pathway on autophagy in granulosa cells of polycystic ovary syndrome (PCOS) rats...

2022-03-23
【Animal Modeling】-Evaluation of the effect of midazolam and butorphanol on anesthesia in mice before isoflurane anesthesia

【Animal Modeling】-Evaluation of the effect of midazolam and butorphanol on anesthesia in mice before isoflurane anesthesia

To observe the anesthesia effect and internal environment stability of mice receiving midazolam combined with butorphanol before isoflurane anesthesia, and evaluate the safety...

2022-03-23
【Animal Modeling】-Effect of Protein Phosphatase 5 (PP5) on Fat Metabolism in Mice

【Animal Modeling】-Effect of Protein Phosphatase 5 (PP5) on Fat Metabolism in Mice

To explore the role of PP5 in fat metabolism in mice using protein phosphatase 5 (PP5) knockout mice...

2022-03-23
【Animal Modeling】-Miniature Pig Model of Spontaneous Periodontitis

【Animal Modeling】-Miniature Pig Model of Spontaneous Periodontitis

Spontaneous gingivitis spreads in the mouth of miniature pigs, and a large amount of food residues are often left on the edge of the gums after eating, so the periodontal tissue is not clean, and dental plaque and stones are easy to form...

2022-03-23
【Animal modeling】-Establishment and application of a method for detecting the copy number of porcine endogenous retrovirus based on droplet digital PCR technology

【Animal modeling】-Establishment and application of a method for detecting the copy number of porcine endogenous retrovirus based on droplet digital PCR technology

To optimize the detection method of porcine endogenous retrovirus copy number in pig genome by using droplet digital PCR technology, and to establish a detection method for PERV copy number...

2022-03-23
【Animal Modeling】-Anti-depressant effect of luteolin on chronic unpredictable mild stress mice

【Animal Modeling】-Anti-depressant effect of luteolin on chronic unpredictable mild stress mice

To observe the effect of hyaluronan on antidepressant, and to preliminarily explore its possible mechanism of action...

2022-03-22
【Animal Modeling】-Application of Nile Red Tracer Nanoparticles in In Vivo Imaging of Tumor-bearing Nude Mice

【Animal Modeling】-Application of Nile Red Tracer Nanoparticles in In Vivo Imaging of Tumor-bearing Nude Mice

To encapsulate Nile Red into nano-formulations, and use its fluorescence properties to investigate the tumor targeting and tissue distribution of nano-formulations in tumor-bearing mice...

2022-03-22
【Animal Modeling】-Experimental Study on Coptis Rhizoma Polysaccharide Relieves Kidney Injury in Diabetic Rats by Inhibiting Oxidative Stress and Inflammatory Response

【Animal Modeling】-Experimental Study on Coptis Rhizoma Polysaccharide Relieves Kidney Injury in Diabetic Rats by Inhibiting Oxidative Stress and Inflammatory Response

To study the protective effect and potential mechanism of Coptis chinensis polysaccharide on renal injury in diabetic rats...

2022-03-22
【Animal Modeling】-Observation of neurotoxicological effects of flame retardant TCPP exposure in mice and related mechanisms

【Animal Modeling】-Observation of neurotoxicological effects of flame retardant TCPP exposure in mice and related mechanisms

To investigate the neurotoxicological effects of flame retardant TCPP exposure in mice and related mechanisms...

2022-03-22
【Animal modeling】-3M tissue glue and electrocoagulation for hemostasis in nephrectomy in uremic rats

【Animal modeling】-3M tissue glue and electrocoagulation for hemostasis in nephrectomy in uremic rats

To compare the application of two hemostatic methods in rat uremic model...

2022-03-22
【Animal modeling】-Effect of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats

【Animal modeling】-Effect of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats

To evaluate the effects of metformin, aerobic exercise and the combined intervention of metformin and aerobic exercise on vascular oxidative stress in type 2 diabetic rats...

2022-03-22
【Animal modeling】-The neuroprotective effect of artesunate on experimental autoimmune encephalomyelitis mice and the effect of autophagy

【Animal modeling】-The neuroprotective effect of artesunate on experimental autoimmune encephalomyelitis mice and the effect of autophagy

To investigate the neuroprotective effect and autophagy of artesunate on experimental autoimmune encephalomyelitis (EAE) mice...

2022-03-22