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【Animal Modeling】-5-Fluorouracil-induced chemotherapeutic intestinal mucositis model in mice

【Animal Modeling】-5-Fluorouracil-induced chemotherapeutic intestinal mucositis model in mice

Study 5-Fluorouracil induces chemotherapeutic intestinal mucositis animal model in mice...

2021-11-29
【Animal Modeling】-Animal Model of Atrioventricular Block

【Animal Modeling】-Animal Model of Atrioventricular Block

Injecting a certain amount of absolute ethanol into the atrioventricular node of experimental animals or applying video energy will damage the myocardial conduction tissue and create an animal model of atrioventricular block...

2021-11-29
Localization and expression analysis of vitamin D receptor in the duodenum of C57BL/6 mice

Localization and expression analysis of vitamin D receptor in the duodenum of C57BL/6 mice

To investigate the location and expression of vitamin D receptor (VDR) in the duodenum of C57BL/6 mice, and to study the correlation between the vitamin D system and the intestinal development process...

2021-11-29
[Animal Modeling]-Scientists have identified compounds that can stimulate muscle cells in mice

[Animal Modeling]-Scientists have identified compounds that can stimulate muscle cells in mice

Researchers at the University of California, Los Angeles have identified compounds that can replicate exercise effects in mouse muscle cells...

2021-11-29
[Animal modeling]-Exposure of monoclonal antibodies in the cerebrospinal fluid of rats and cynomolgus monkeys after systemic administration

[Animal modeling]-Exposure of monoclonal antibodies in the cerebrospinal fluid of rats and cynomolgus monkeys after systemic administration

The blood-brain barrier (BBB) is the most significant obstacle to the targeted delivery of therapeutic drugs to the central nervous system (CNS)...

2021-11-29
【Animal Modeling】-The influence of different formula feeds on the establishment of DEN-induced liver cancer model in mice

【Animal Modeling】-The influence of different formula feeds on the establishment of DEN-induced liver cancer model in mice

Establish a diethylnitrosamine (DEN)-induced mouse liver cancer model, and use two formula foods: SPF-grade mice and rats complete compound diet and AIN93-G combined synthetic diet to establish an effect-induced small Mouse liver cancer model...

2021-11-29
【Disease animal model】-rat acute psychological stress model

【Disease animal model】-rat acute psychological stress model

SD rats, 8 weeks old, male. The laboratory temperature is 18-25℃, regular feeding, free eating and drinking...

2021-11-29
[Animal Modeling]-Liver Fibrosis Model Induced by Serum Immunization

[Animal Modeling]-Liver Fibrosis Model Induced by Serum Immunization

Reproduction method Human serum albumin 4 mg/head was injected subcutaneously into female Wistar rats weighing 120 to 150 g at the same dose on the 1, 15, 25 and 35 days, and human serum albumin was injected into normal physiology brine. Then emulsif...

2021-11-29
Construction and preliminary application of human tumor xenograft model of liver cancer

Construction and preliminary application of human tumor xenograft model of liver cancer

Establish a xenotransplantation model of human liver cancer and explore its role in precision medicine for liver cancer...

2021-11-29
[Animal Modeling]-Cysteamine-induced duodenal ulcer animal model

[Animal Modeling]-Cysteamine-induced duodenal ulcer animal model

Feeding method Adult rats fasted for 24 hours, after subcutaneously administering 400mg/kg body weight or 300mg/kg body weight of amine hydrochloride hydrochloride, the same route was given at a dose of 100mg/kg body weight...

2021-11-26
【Animal Modeling】-animal model of dystrophic liver cirrhosis

【Animal Modeling】-animal model of dystrophic liver cirrhosis

Feeding method Weaned male rats are fed a choline-deficient low-protein and high-fat diet at a dose of 8-10g per day for 2-3 months...

2021-11-26
【Animal Modeling】-Dinitrochlorobenzene-induced ulcerative colitis animal model

【Animal Modeling】-Dinitrochlorobenzene-induced ulcerative colitis animal model

Replication method Adult male BALB/c mice, abdomen (without skin damage) approximately 2.0 cm x 1.5 cm, in acetone olive oil solution with 3.3% 2,4-dinitrochlorobenzene (DNCB) (ratio 1:1) Smear specimen to abdominal incision, once a day, 50μl each ti...

2021-11-26
[Animal Modeling]-Embryo chorioallantoic membrane transplantation tumor model

[Animal Modeling]-Embryo chorioallantoic membrane transplantation tumor model

Compare the growth of three different cancer cell lines in chicken chorionic villi (CAM), screen the best transplanted cancer cell lines, establish transplanted tumor models and observe their biological characteristics...

2021-11-26
【Animal Modeling】-Reproduce the co-evolution of HIV envelope protein Env and broadly neutralizing antibodies in rhesus monkeys, laying the foundation for the development of efficient HIV vaccines

【Animal Modeling】-Reproduce the co-evolution of HIV envelope protein Env and broadly neutralizing antibodies in rhesus monkeys, laying the foundation for the development of efficient HIV vaccines

The development of effective neutralizing antibody-based HIV-1 vaccines involves the homogenization of multiple immunoglobulin receptors that express the specificity of one or more classical broadly neutralizing antibody (bNAb) epitope clusters Recog...

2021-11-26
【Animal modeling】-Establishment of gastric cancer metastasis model

【Animal modeling】-Establishment of gastric cancer metastasis model

How to establish gastric cancer metastasis models based on clinical tumor specimens and provide individual animal models for gastric cancer metastasis research...

2021-11-26
Establishment of a tree shrew model of Fusarium solani keratitis

Establishment of a tree shrew model of Fusarium solani keratitis

Use clinically isolated Fusarium solani to infect the cornea of tree shrews to establish a tree shrew model of Fusarium solani keratitis...

2021-11-26