To observe the effects of different doses of protease inhibitors on rat behavior and the expression of tyrosine hydroxylase and α-synuclein in the substantia nigra, and to explore the optimal conditions for a chronic model of PSI-induced Parkinson\'s...
2022-09-05To evaluate the modeling effect of different concentrations of doxorubicin-induced cardiotoxicity model in mice based on pathological changes...
2022-09-05To observe the effect of substantia nigra overexpressing lysosome-associated membrane protein 2A up-regulating molecular chaperone-mediated autophagy on the motor behavior of experimental monkeys in a rhesus monkey model of Parkinson\'s disease...
2022-09-05The purpose of this study is to explore the establishment of a reliable disease-syndrome combination animal model of Alzheimer\'s disease and phlegm-stasis syndrome, to provide a corresponding animal model for the prevention and treatment of AD with ...
2022-09-05To observe the changes of intestinal flora in Wuzhishan miniature pig atherosclerosis model induced by high-fat and high-sugar diet...
2022-09-05The common cotton-eared marmoset is a small non-human primate experimental animal. It has the advantages of low feeding cost, high reproductive efficiency, and short sexual maturity. It is very suitable for assisted reproductive technology and geneti...
2022-09-02To construct a rat model of gastritis-carcinoma transformation, and to explore new serological indicators for early gastric cancer...
2022-09-02To establish a hypertensive model of Bama miniature pigs with a high-fat and high-salt diet, and to explore its possible pathogenesis...
2022-09-02To establish a reasonable and stable mouse model of hyperuricemia nephropathy, and to provide a pathological model for screening and researching drugs for the treatment of hyperuricemia nephropathy...
2022-09-02Scientists at the Hub Hubrecht Institute (KNAW) and Cambridge University (UK) have successfully produced complex embryo-like structures from mouse embryonic stem cells. These structures, called gastric colloids, allow the ovaries to grow for the firs...
2022-09-02To investigate the effect of different doses of propofol on the expression of MTA1 and Wnt1 in rat MADB106 cells lung metastasis and tumor tissue...
2022-09-02To investigate the relationship between the establishment of tree shrew gallstone model and substance P by feeding tree shrew with high cholesterol diet...
2022-09-02To investigate the effect of paclitaxel on the expression of CD28 and CTLA-4 in the brain tissue of rats with experimental autoimmune encephalomyelitis and the content of B cell stimulating factor (BAFF) in the supernatant of spleen tissue and its si...
2022-09-02To determine the LD50 value of mice intravenously administered with Asarum injection preparation, and to draft the abnormal toxicity inspection standard of this product...
2022-09-02To understand the dynamic changes and regularities of gene expression levels of metallothioneins (MTs) in the development of mouse hepatocellular carcinoma (HCC), and to explore the significance of MTs in the development of HCC...
2022-09-02To observe whether vitamin C (Vc) can promote the proliferation of bone marrow mesenchymal stem cells (BMMSCs) derived from aging individuals by increasing telomerase activity...
2022-09-02