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【Animal modeling】-Effect of lamotrigine on the expression of PGP, MVP and amino acid content in the hippocampus of chronic epilepsy rats

【Animal modeling】-Effect of lamotrigine on the expression of PGP, MVP and amino acid content in the hippocampus of chronic epilepsy rats

To investigate the effect of lamotrigine on the expression and amino acid content of P-glycoprotein and main vault protein in the hippocampus of chronic epilepsy rats...

2022-07-11
【Animal Modeling】-Protein Transformation Regulation Mechanism of Rat Skeletal Muscle Atrophy Induced by Hypoxia Exposure

【Animal Modeling】-Protein Transformation Regulation Mechanism of Rat Skeletal Muscle Atrophy Induced by Hypoxia Exposure

To compare the differences in the expression of genes related to protein synthesis and decomposition in skeletal muscle of rats under hypoxic exposure and paired hypoxic feeding intervention (semi-starvation state) under normoxia, in order to explore...

2022-07-11
【Animal Modeling】-Effect of fasting time on glucose tolerance and insulin secretion in Kunming mice

【Animal Modeling】-Effect of fasting time on glucose tolerance and insulin secretion in Kunming mice

In order to explore the stable, reliable and reasonable fasting time of OGTT in Kunming mice, which are used the most in China in a specific environment...

2022-07-11
【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

To investigate the mechanism of human umbilical cord mesenchymal stem cell transplantation in repairing ovarian function in rats with premature ovarian failure...

2022-07-11
【Animal Modeling】-Effects of Different Exercise Mode Interventions on Emotional Behavior in Aggressive Rats

【Animal Modeling】-Effects of Different Exercise Mode Interventions on Emotional Behavior in Aggressive Rats

To investigate the effects of different exercise interventions on emotional behavior of aggressive rats...

2022-07-08
【Animal modeling】-Discuss the protective effect and mechanism of activated protein C on myocardial ischemia-reperfusion injury in rats

【Animal modeling】-Discuss the protective effect and mechanism of activated protein C on myocardial ischemia-reperfusion injury in rats

To investigate the protective effect and mechanism of activated protein C (APC) on myocardial ischemia-reperfusion injury in rats...

2022-07-08
【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

To apply hypoxic training to obese mice to observe the changes of GHSR levels in gastric tissue and hypothalamus, so as to explore whether hypoxic training affects the Ghrelin-GHSR pathway to improve obesity...

2022-07-08
【Animal modeling】-Observation of the effect of thrombopoietin on cardiomyocyte apoptosis in rats with heart failure induced by adriamycin based on TGF-β1/Smad3 signaling pathway

【Animal modeling】-Observation of the effect of thrombopoietin on cardiomyocyte apoptosis in rats with heart failure induced by adriamycin based on TGF-β1/Smad3 signaling pathway

To investigate the effect of thrombopoietin (TPO) on cardiomyocyte apoptosis in rats with adriamycin-induced heart failure (CHF) and its regulatory mechanism on TGF-β1/Smad3 signal...

2022-07-08
【Animal modeling】-Study on the protective effect of curcumin on cognitive function and neurological function in mice with cerebral ischemia-reperfusion injury

【Animal modeling】-Study on the protective effect of curcumin on cognitive function and neurological function in mice with cerebral ischemia-reperfusion injury

To investigate the effect of curcumin on cognitive function, neurological function and mechanism of cerebral ischemia-reperfusion injury in mice...

2022-07-08
【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

To observe the effect of hydroxychloroquine on the distribution of lymphocytes in peripheral immune organs (spleen) of mice with systemic lupus erythematosus (TC mice)...

2022-07-08
【Animal Modeling】-Study on the antitumor effect of Xiuzhen mushroom powder on H22 tumor-bearing mice in vivo

【Animal Modeling】-Study on the antitumor effect of Xiuzhen mushroom powder on H22 tumor-bearing mice in vivo

The purpose of this experiment was to study the anti-tumor effect of Xiuzhen Mushroom and its anti-tumor mechanism...

2022-07-08
【Animal Modeling】-Comparison of Depression and Anxiety-like Behaviors in Mice of Different Ages

【Animal Modeling】-Comparison of Depression and Anxiety-like Behaviors in Mice of Different Ages

To observe and compare the depression and anxiety-like behaviors of experimental mice of different ages...

2022-07-08
【Animal Modeling】-an open source multifunctional animal behavioral experimental system

【Animal Modeling】-an open source multifunctional animal behavioral experimental system

To provide a multifunctional animal behavioral experimental system based on an open source sharing protocol, which can be used for conditioned fear, active avoidance and other behavioral observation, training and testing...

2022-07-08
【Animal modeling】-The effect of simulated aging rat astrocyte conditioned medium on the proliferation of neural stem cells

【Animal modeling】-The effect of simulated aging rat astrocyte conditioned medium on the proliferation of neural stem cells

To establish a rat astrocyte aging model, simulate the aging of astrocytes in aged rats, and explore the effect of aging astrocyte conditioned medium on the proliferation of neural stem cells...

2022-07-08
【Animal Modeling】-Effect and mechanism of acute liver injury in mice on brown adipose tissue function

【Animal Modeling】-Effect and mechanism of acute liver injury in mice on brown adipose tissue function

To investigate the effects of carbon tetrachloride (CC14 ) on brown adipose tissue in mice with acute liver injury at different time points and the related mechanisms...

2022-07-08
【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

【Animal modeling】-Effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats

To observe the effect of astragaloside IV on inflammatory factors and ultrastructure in cerebral ischemia-reperfusion rats...

2022-07-08