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[Animal modeling]-Intestinal microbes affect the activity of immune cells in the brain of multiple sclerosis mice

[Animal modeling]-Intestinal microbes affect the activity of immune cells in the brain of multiple sclerosis mice

Changes in the intestinal flora have changed the activity of immune cells in the brains of experimental multiple sclerosis (MS) mice...

2022-02-04
【Animal Modeling】-N-Acetylcysteineamide Prevents and Reverses Sodium Selenite-induced Cataract in Rats: Experimental Study

【Animal Modeling】-N-Acetylcysteineamide Prevents and Reverses Sodium Selenite-induced Cataract in Rats: Experimental Study

The lens that affects vision gradually loses transparency and forms cataracts. The pathogenesis of cataract is multi-factorial, and the mechanism involved is not fully understood. Oxidative stress is the primary cause of cataract formation....

2022-02-04
【Animal Modeling】-Scientists use stem cell injection to treat alcoholic laboratory mice

【Animal Modeling】-Scientists use stem cell injection to treat alcoholic laboratory mice

A recent study published in Scientific Reports showed that intravenous injection of anti-inflammatory mesenchymal stem cell spheroids can inhibit chronic alcohol intake and reduce alcohol consumption...

2022-02-04
【Animal Modeling】-Drosophila model reveals cancer consumption mechanism

【Animal Modeling】-Drosophila model reveals cancer consumption mechanism

The gradual loss of muscle and adipose tissue throughout the body is one of the most obvious and painful clinical manifestations of cancer, but no one knows how it degenerates distant tissues...

2022-02-04
【Animal Modeling】-The protective effect of mild hypothermia on radiation-induced lung injury in rats

【Animal Modeling】-The protective effect of mild hypothermia on radiation-induced lung injury in rats

To explore the protective effect of mild hypothermia on radiation-induced lung injury and compare it with the commonly used anti-radioactive drug Amifostine...

2022-02-04
[Animal Modeling]-Mouse experiments reveal that obesity can also make the sense of taste dull?

[Animal Modeling]-Mouse experiments reveal that obesity can also make the sense of taste dull?

Previous studies have shown that weight gain will reduce the body’s sensitivity to food taste, and the sense of smell can be restored with weight loss...

2022-02-04
【Animal Modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

【Animal Modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

Construct the eukaryotic expression vector pEGFPN1/IL-37b of full-length mature IL-37b, and detect its expression in RAW264.7 cells...

2022-02-04
【Animal Modeling】-Mice experiments revealed that excessive diet during lactation will affect the health of children

【Animal Modeling】-Mice experiments revealed that excessive diet during lactation will affect the health of children

A new study on mice shows that breastfeeding women who eat too much may increase their risk of obesity and puberty in the future, which can lead to diabetes and other infertility...

2022-02-04
[Animal Modeling] The effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

[Animal Modeling] The effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

To investigate the effect of artificial recombinant botulinum toxin type A heavy chain (BoNT/A heavy chain) on the expression of local growth-related proteins in rat spinal cord injury and promote neurite regeneration. It provides evidence to clarify...

2022-02-04
【Animal modeling】-Selective cathepsin K inhibitor MIV-711 reduces joint pathology in animal models of osteoarthritis

【Animal modeling】-Selective cathepsin K inhibitor MIV-711 reduces joint pathology in animal models of osteoarthritis

Osteoarthritis (OA) is a common musculoskeletal disease characterized by damage to the joint structure, leading to symptoms such as joint stiffness and pain...

2022-02-04
【Animal Modeling】-Xueshuantong Capsule\\

【Animal Modeling】-Xueshuantong Capsule

How to study the protective effect of Panax Notoginseng Saponins (PNS) and its monomer Rg1? b1 affects the tight junction damage of vascular endothelium caused by oxygen glucose deprivation (OGD)...

2022-02-04
【Animal Modeling】-The effect of high-fat feed feeding time on type 2 diabetic nephropathy rat model

【Animal Modeling】-The effect of high-fat feed feeding time on type 2 diabetic nephropathy rat model

To explore the effect of high-fat diet feeding time on blood glucose, insulin resistance index (HOMA-IR) and urinary albumin excretion rate (UAER) in type 2 diabetic nephropathy (DN) rats...

2022-02-04
【Animal modeling】-Bleomycin-induced pulmonary fibrosis model

【Animal modeling】-Bleomycin-induced pulmonary fibrosis model

Bleomycin (bleomycin) is a polypeptide anti-tumor drug, and its mechanism of causing pulmonary interstitial fibrosis is mainly through the action of reactive oxygen species. In the early stage of lung injury caused by bleomycin, that is, the alveolit...

2022-02-04
【Animal Modeling】-The effect of TRPV4 receptor on the renal damage induced by angiotensin II in mice

【Animal Modeling】-The effect of TRPV4 receptor on the renal damage induced by angiotensin II in mice

Use transient receptor potential vanilloid type 4 (TRPV4) gene knockout (TRPV4-/-) mice to study the role of TRPV4 receptor in kidney damage caused by angiotensin II (angiotensin II, Ang II) effect...

2022-02-04
How to prepare animal model of blood stasis syndrome?

How to prepare animal model of blood stasis syndrome?

Congestion syndrome (blood loss syndrome) is caused by qi deficiency, qi stagnation, hot toxins, cold blood, etc., blocking blood flow and accumulating in the meridians or organs...

2022-02-04
[Animal Modeling] Japan has developed a new bioluminescence system that can observe brain activity in living animals

[Animal Modeling] Japan has developed a new bioluminescence system that can observe brain activity in living animals

Japan Institute of Physical Chemistry has developed a new type of bioluminescence system that can observe the brain activity of living animals...

2022-02-04