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【Animal Modeling】-How to create a thin mouse model of endometrium?

【Animal Modeling】-How to create a thin mouse model of endometrium?

Further explore the possibility of establishing a stable thin endometrial mouse model by injecting 95 tanol into the uterine cavity through immunohistochemistry and fertility assessment. This model is an ideal animal for thin endometrial. Provide rel...

2021-12-16
【Animal Modeling】-Modeling of ovarian insufficiency mice

【Animal Modeling】-Modeling of ovarian insufficiency mice

Compare and analyze the differences of the three commonly used modeling methods in the primary ovarian insufficiency (POI) mouse model to study the modeling methods that meet the clinical characteristics of POI...

2021-12-16
【Animal Modeling】-Establishment of a mouse model of IgA nephropathy induced by superantigen Staphylococcal enterotoxin B

【Animal Modeling】-Establishment of a mouse model of IgA nephropathy induced by superantigen Staphylococcal enterotoxin B

Establish a mouse IgA nephropathy model and observe its biochemical and pathological characteristics...

2021-12-16
【Animal Modeling】-HBV transgenic mouse model

【Animal Modeling】-HBV transgenic mouse model

Establish transgenic mice expressing part or all of the HBV genome, and study the mechanism of HBV replication, the expression of viral genes in liver cell injury, and HBV immunopathology...

2021-12-16
【Animal Modeling】-How to establish a rodent experimental model of chronic prostatitis?

【Animal Modeling】-How to establish a rodent experimental model of chronic prostatitis?

Chronic aseptic prostatitis (CAP) or chronic pelvic pain syndrome (CPPS) is the most common type of prostatitis in clinic, accounting for more than 90 years of age, and is a common disease in urology...

2021-12-16
[Animal Modeling]-How to establish a fluorescent PCR detection method for mouse polyomavirus?

[Animal Modeling]-How to establish a fluorescent PCR detection method for mouse polyomavirus?

Establish a fluorescent quantitative PCR detection method for polyoma virus to explore the situation of naked mole mouse polyoma virus infection...

2021-12-16
【Animal Modeling】-Research on Animal Model of Renal Vascular Hypertension

【Animal Modeling】-Research on Animal Model of Renal Vascular Hypertension

Renal vascular hypertension is the stenosis or obstruction of the main trunk or branches of the renal arteries on one or both sides, which reduces the flow of renal blood vessels and leads to hypertension caused by renal ischemia. It is the most comm...

2021-12-15
[Disease animal modeling]-Rabbit electrical stimulation of the heart causes ventricular arrhythmia

[Disease animal modeling]-Rabbit electrical stimulation of the heart causes ventricular arrhythmia

New Zealand rabbits weighing about 2.5kg are anesthetized by intravenous injection of 3% sodium pentobarbital at a dose of 30mg/kg body weight, and fixed in lateral position; needle electrodes are pierced into the rabbit’s limbs and connected to the...

2021-12-15
【Animal Modeling】-Comparison of liver toxicity between matrine and oxymatrine in vitro and in vivo models

【Animal Modeling】-Comparison of liver toxicity between matrine and oxymatrine in vitro and in vivo models

Compare the liver toxicity of matrine (MT) and oxymatrine (OMT), study the severity and characteristics of its toxicity, and first clarify its toxicity mechanism?...

2021-12-15
【Animal Modeling】-Inactivated H37Rv whole bacterial sensitization model

【Animal Modeling】-Inactivated H37Rv whole bacterial sensitization model

Tuberculosis is a chronic infectious disease that is zoonotic. It is highly pathogenic and lethal worldwide and is caused by Mycobacterium tuberculosis....

2021-12-15
【Animal Modeling】-The effect of ghrelin on the expression of hippocampus DKK-1 and the function of learning and memory in diabetic rats

【Animal Modeling】-The effect of ghrelin on the expression of hippocampus DKK-1 and the function of learning and memory in diabetic rats

Observe the changes in the expression of ghrelin in DKK-1 and WNT signaling pathways in diabetic rats, and explore the mechanism of its involvement in learning and memory functions...

2021-12-15
【Animal Modeling】-Schizophrenia Model

【Animal Modeling】-Schizophrenia Model

Establish a rat model of schizophrenia, observe the pathological damage of the prefrontal cortex and the expression changes of PKA and endothelial cell chemokine-5, clarify the mechanism of nerve damage, and guide clinical treatment. Does it provide...

2021-12-15
【Animal Model】-A new model of rat artery transplantation

【Animal Model】-A new model of rat artery transplantation

Allograft vascular disease (AV) limits the function and long-term survival of transplanted organs. This is the most pressing global issue in the field of organ transplantation...

2021-12-15
【Animal Modeling】-Rabbit Chlamydia Pneumoniae

【Animal Modeling】-Rabbit Chlamydia Pneumoniae

Breeding method First take out a 1-month-old New Zealand rabbit, hyperventilate under mild halothane anesthesia, and then inoculate 1.0×10000000?5.0×10000000 CFU/ml pure chlamydial pneumonia from its turbinate...

2021-12-15
[Animal Modeling]-Rats with Ocular Ischemic Syndrome

[Animal Modeling]-Rats with Ocular Ischemic Syndrome

Establish a rat ocular ischemic syndrome model, observe the morphology of the retina after ischemia and the difference in the expression of RhoA and ROCK-2 in the rat retina...

2021-12-15
[Disease animal model]-Spontaneous fatty liver animal model

[Disease animal model]-Spontaneous fatty liver animal model

Due to the mutation of the key gene of fat metabolism in liver cells, the fat metabolism disorder is caused, which leads to the imbalance of liver fat input and output....

2021-12-15