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[Animal Modeling]-The newly designed master protease inhibitor can inhibit neocoronavirus infection in vitro and in transgenic mouse models

[Animal Modeling]-The newly designed master protease inhibitor can inhibit neocoronavirus infection in vitro and in transgenic mouse models

The new coronavirus SARS-CoV-2 caused the Coronavirus Disease (COVID-19) in 2019 and is currently rampant worldwide. Vaccines are urgently needed to control the pandemic...

2021-12-23
【Animal Modeling】-The traction model of the ventral nerve root of the lumbar spine

【Animal Modeling】-The traction model of the ventral nerve root of the lumbar spine

To study the etiology and drug development of amyotrophic lateral sclerosis, establish a fourth lumbar-abdominal root traction rat model, and use brain-derived neurotrophic factor as a positive drug to evaluate the effectiveness of the model. Do you...

2021-12-23
【Disease Animal Model】-Abortion Animal Model

【Disease Animal Model】-Abortion Animal Model

Abortion is a common disease in gynecology, and its etiology is more complicated. Commonly used abortion animal models include drug-induced abortion, bromocriptine-induced abortion, kidney-deficiency abortion and repeated spontaneous abortion models,...

2021-12-23
What are the ECG characteristics of the pressure-overloaded chronic heart failure rat model? -【Animal Modeling】

What are the ECG characteristics of the pressure-overloaded chronic heart failure rat model? -【Animal Modeling】

Use electrocardiogram to detect and analyze the characteristics of chronic heart failure rats with pressure overload...

2021-12-23
【Animal Modeling】-Improvement and evaluation of rat myocardial ischemia reperfusion injury model

【Animal Modeling】-Improvement and evaluation of rat myocardial ischemia reperfusion injury model

Improve the preparation of the rat acute myocardial ischemia-reperfusion injury (MI/RI) model and conduct a comprehensive evaluation to lay a good model foundation for subsequent MI/RI research...

2021-12-23
【Animal Modeling】-How to establish a closed tibia fracture model in rats?

【Animal Modeling】-How to establish a closed tibia fracture model in rats?

Based on the model previously designed by Bonnarens et al., the rat fracture model is described...

2021-12-23
[Animal Modeling]-How to establish a SD rat model of high altitude pulmonary edema?

[Animal Modeling]-How to establish a SD rat model of high altitude pulmonary edema?

To study the effects of various hypoxic stress methods on the establishment of high altitude pulmonary edema models...

2021-12-23
【Animal Modeling】-Comparison of the pathological characteristics of collagen-induced rheumatoid arthritis in Wistar and Lewis rats

【Animal Modeling】-Comparison of the pathological characteristics of collagen-induced rheumatoid arthritis in Wistar and Lewis rats

To study the differences in symptoms and pathological characteristics between Wistar and Lewis rat rheumatoid arthritis (RA) models induced by bovine type II collagen?...

2021-12-23
【Animal Modeling】-Canine Lumbar Spinal Canal Stenosis Model

【Animal Modeling】-Canine Lumbar Spinal Canal Stenosis Model

Breeding method After anesthetizing the experimental dog from the great saphenous vein with 3% pentobarbital sodium 30mg/kg body weight, perform tracheal intubation and shave the waist and fix it on the operating table...

2021-12-23
[Animal Modeling]-Effect of lentiviral vector-mediated HCV receptor gene OCLN/CD81 transfection on bone marrow mesenchymal stem cells of tree shrews

[Animal Modeling]-Effect of lentiviral vector-mediated HCV receptor gene OCLN/CD81 transfection on bone marrow mesenchymal stem cells of tree shrews

Observe the effect of lentiviral vector transfection with HCV receptor gene OCLN/CD81 on the biological characteristics and gene expression of tree bone marrow mesenchymal stem cells under in vitro culture conditions?...

2021-12-23
Ultrastructure observation of the blood-brain barrier in a lung cancer brain metastasis model in nude mice

Ultrastructure observation of the blood-brain barrier in a lung cancer brain metastasis model in nude mice

Using Lantern Tracer Nitrate Electron Microscope to Observe the Ultrastructure of the Blood Brain Barrier in Nude Mice with Lung Cancer Brain Metastasis Model...

2021-12-23
【Animal Modeling】-Why do we need to establish a model of poultry hyperuricemia?

【Animal Modeling】-Why do we need to establish a model of poultry hyperuricemia?

Hyperuricemia (HUA) is a metabolic disease caused by abnormal purine metabolism associated with gout, cardiovascular and cerebrovascular diseases and metabolic syndrome...

2021-12-23
【Animal Modeling】-Acute rabbit atherosclerotic plaque animal model caused by the combination of high cholesterol feeding method and immune method

【Animal Modeling】-Acute rabbit atherosclerotic plaque animal model caused by the combination of high cholesterol feeding method and immune method

Breeding method Place adult male rabbits in a separate cage for observation for 1 week, record fasting weight, collect blood to measure various blood lipid indexes, and then inject bovine serum albumin intravenously once...

2021-12-23
How to do transjugular liver biopsy in minipigs? -【Animal Modeling】

How to do transjugular liver biopsy in minipigs? -【Animal Modeling】

To explore the feasibility and safety of using Cook Company\\\'s LBS200 intrahepatic biopsy device for transjugular liver biopsy (TJLB)...

2021-12-22
[Animal modeling]-Schisandra syrup on bronchial asthma in mice

[Animal modeling]-Schisandra syrup on bronchial asthma in mice

Bronchial asthma is a common chronic airway inflammatory disease with the characteristics of long duration and recurrence...

2021-12-22
【Animal Modeling】-Models of different degrees of chills

【Animal Modeling】-Models of different degrees of chills

To study the temperature threshold of shivering in cryotherapy of hyperthermia rats, and to establish rat models with different degrees of shivering...

2021-12-22
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