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[Animal Modeling]-Model of liver fibrosis induced by common bile duct ligation

[Animal Modeling]-Model of liver fibrosis induced by common bile duct ligation

Replication method Adult rat, open the abdominal cavity after anesthesia, find and release the common bile duct in the duodenal descending mesentery, pass two silk threads under it, and make a \\\"V\\\"-shaped incision to the liver...

2021-12-09
【Animal Modeling】-How to establish a mouse model of drug-resistant Candida albicans diffuse infection?

【Animal Modeling】-How to establish a mouse model of drug-resistant Candida albicans diffuse infection?

Establish a mouse model of diffuse infection of drug-resistant Candida albicans to screen new drugs...

2021-12-09
[Animal Modeling]-Spinal Cord Compression Injury Model

[Animal Modeling]-Spinal Cord Compression Injury Model

Spinal cord compression is one of the important causes of spinal cord injury. The injury model mainly simulates spinal cord injury caused by spinal cord space-occupying lesions, which can be divided into acute compression injury and chronic compressi...

2021-12-09
【Disease Animal Model】-Naphthalene-induced Cataract Animal Model

【Disease Animal Model】-Naphthalene-induced Cataract Animal Model

Naphthalene can increase the reactive oxygen species in rabbit cells, increase the production of free radicals, increase peroxide damage, damage the lipids in the lens cell membrane, and cause experimental cataracts...

2021-12-09
【Animal Modeling】-Water immersion restraint method induced stress gastric ulcer animal model

【Animal Modeling】-Water immersion restraint method induced stress gastric ulcer animal model

Feeding method Adult rats fasted with water for 24 hours, anesthetized with ether, and fixed the animal\\\'s limbs and neck on the rat board....

2021-12-09
【Animal Model】-Animal Model of Sinus Arrhythmia

【Animal Model】-Animal Model of Sinus Arrhythmia

Using mechanical or chemical methods to directly damage the sinus node area, local myocardial ischemia and necrosis, agitation and conduction disorders, decreased heart rate, sinus block, sinus block or junctional stroke and slow syndrome, causing pr...

2021-12-09
[Animal Modeling]-Rat lumbar ventral nerve root traction model

[Animal Modeling]-Rat lumbar ventral nerve root traction model

To study the etiology and drug development of amyotrophic lateral sclerosis, establish a rat model of fourth lumbar-abdominal root traction, and use brain-derived neurotrophic factor as a positive drug to verify the effectiveness of the model. Do you...

2021-12-09
【Animal Modeling】-miRNA-144 gene overexpression has antitumor effect on liver cancer mice and its influence on intestinal flora

【Animal Modeling】-miRNA-144 gene overexpression has antitumor effect on liver cancer mice and its influence on intestinal flora

Analyze the anti-tumor effect of microRNA-144 (miRNA-144) gene overexpression on liver cancer mice and its influence on the intestinal flora. How to establish ascites liver cancer transplanted into mice?...

2021-12-09
【Animal Modeling】-Efficacy of Eucommia ulmoides extract on mice with mastitis induced by lipopolysaccharide and the way of action

【Animal Modeling】-Efficacy of Eucommia ulmoides extract on mice with mastitis induced by lipopolysaccharide and the way of action

To study the therapeutic effect and action path of eucommia extract on mice with mastitis...

2021-12-09
[Animal modeling]-RNA interference specifically blocks the effect of local angiotensin Ⅱ type 1 receptors on the first-phase insulin secretion in pancreatic islets

[Animal modeling]-RNA interference specifically blocks the effect of local angiotensin Ⅱ type 1 receptors on the first-phase insulin secretion in pancreatic islets

Observe the changes of insulin secretion in db/db mouse pancreatic islets after blocking the expression of local angiotensin II type 1 receptor (AT1R) by RNA interference technology, and explore its underlying mechanism...

2021-12-07
【Animal Modeling】-Animal Model of Ureaplasma Urealyticum Infection

【Animal Modeling】-Animal Model of Ureaplasma Urealyticum Infection

Study the advantages and disadvantages of various modeling techniques, and choose the most suitable animal model method to infect Ureaplasma...

2021-12-07
【Animal Modeling】-Why build animal models of post-traumatic osteoarthritis?

【Animal Modeling】-Why build animal models of post-traumatic osteoarthritis?

Abstract: Osteoarthritis (Osteoarthritis, OA) is a common inflammatory joint disease that affects the growth and development of the elderly and has a strong socio-economic impact....

2021-12-07
Reveal the molecular mechanisms and processes that turn on tissue repair in inflammatory bowel disease

Reveal the molecular mechanisms and processes that turn on tissue repair in inflammatory bowel disease

Recently, in a research report published in the international journal Gut, scientists from Leuven University and other institutions have developed a new method through research on humans and mice, which can direct immune system cells to help repair t...

2021-12-07
How to establish a murine necrotizing enterocolitis model? -Animal modeling

How to establish a murine necrotizing enterocolitis model? -Animal modeling

Improve and compare methods for establishing necrotizing enterocolitis (NEC) animal models commonly used at home and abroad, and clarify simple and effective NEC modeling methods...

2021-12-07
【Animal Modeling】-How to establish a rat model of acute subdural hematoma caused by blood injection?

【Animal Modeling】-How to establish a rat model of acute subdural hematoma caused by blood injection?

To study the effect of different amounts of autologous blood on the stability of rat subdural hematoma model...

2021-12-07
How to do regional anesthesia animal model? -Animal modeling

How to do regional anesthesia animal model? -Animal modeling

Local anesthesia occupies an important position in clinical anesthesia...

2021-12-07