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[Animal Experiment]-The zebrafish has hidden evolutionary steps from fins to limbs

[Animal Experiment]-The zebrafish has hidden evolutionary steps from fins to limbs

Scientists at Harvard University modified the zebrafish to start forming limb-like appendages by regulating a single gene...

2021-10-21
How to build a model of post-traumatic stress disorder? -【Animal Modeling】

How to build a model of post-traumatic stress disorder? -【Animal Modeling】

Post-traumatic stress disorder (PTSD) is a mental illness that has a high incidence and a major impact on the socio-economic situation after experiencing a major traumatic event...

2021-10-21
【Animal Modeling】-The effect of TRPV4 receptor on the renal damage induced by angiotensin II in mice

【Animal Modeling】-The effect of TRPV4 receptor on the renal damage induced by angiotensin II in mice

To study the role of TRPV4 receptor in angiotensin II (angiotensin II, Ang II)-induced nephropathy, this gene uses transient receptor potential vanilloid type 4 (TRPV4) gene knockout (TRPV4-/-) small mouse...

2021-10-21
[Animal Modeling]-Experimental study of TGF-β pathway regulated by miR-335-5P mediating insulin resistance and pancreatic β cell secretion in gestational diabetic mice

[Animal Modeling]-Experimental study of TGF-β pathway regulated by miR-335-5P mediating insulin resistance and pancreatic β cell secretion in gestational diabetic mice

Treatment of gestational diabetes (GDM) mice with miR-335-5P and transforming factor-β (TGF-β), miR-335-5P regulates the TGF-β pathway and promotes pancreatic secretion to clarify, participates in enhancing β cells and insulin resistance as a treatme...

2021-10-21
【Animal Modeling】-How to build a mouse model for vaccine research

【Animal Modeling】-How to build a mouse model for vaccine research

In order to develop vaccines and study the human immune response, scientists rely on a variety of animal models, including mice that can produce human antibodies through genetically engineered B cell receptors, which are specialized antibodies that b...

2021-10-21
【Animal Modeling】-How to establish a depressive rat model?

【Animal Modeling】-How to establish a depressive rat model?

Depression is a mental illness with typical symptoms such as decreased mood, delayed thinking, and decreased speech activity...

2021-10-21
Cell therapy promotes axon remyelination in a mouse model

Cell therapy promotes axon remyelination in a mouse model

Demyelinating diseases, such as multiple sclerosis and leukocyte dystrophy, are characterized by the destruction of the protective myelin sheath surrounding neuronal axons. This demyelination may be due to an autoimmune response or impaired productio...

2021-10-21
【Animal Modeling】-Miniature Pig Mandible Defect Model

【Animal Modeling】-Miniature Pig Mandible Defect Model

10 Chinese experimental miniature pigs aged 18 months, female. Miniature pigs are under conventional anesthesia, and the premolars and first molars of the right mandible are extracted. Two months later, the animals are randomly divided into segmental...

2021-10-21
【Animal Modeling】-How to establish a heart failure model of fruit flies induced by a high-fat diet?

【Animal Modeling】-How to establish a heart failure model of fruit flies induced by a high-fat diet?

To establish a heart failure model of fruit flies induced by a high-fat diet?...

2021-10-21
【Animal Modeling】-8 gene induces reprogramming of mature blood cells in mice into hematopoietic stem cells

【Animal Modeling】-8 gene induces reprogramming of mature blood cells in mice into hematopoietic stem cells

Researchers at Boston Children\\\\\\\'s Hospital have used a mixture of transcription factors composed of eight gene switches to reprogram mature mouse blood cells into hematopoietic stem cells (HSC)...

2021-10-21
[Animal Modeling]-Potential leads to osteoporosis in male mice

[Animal Modeling]-Potential leads to osteoporosis in male mice

To observe the therapeutic effect of bakuchiol on ovariectomized male mice with osteoporosis...

2021-10-21
【Animal Modeling】-Establishment of non-invasive mouse tracheal intubation using disposable epidural anesthesia catheter

【Animal Modeling】-Establishment of non-invasive mouse tracheal intubation using disposable epidural anesthesia catheter

Establish a simple, reliable, and accurate method for non-invasive tracheal intubation in mice inserted into the trachea, which can be used for modeling various mouse lung disease models and drug intervention...

2021-10-20
[Animal Modeling]-Application of Experimental Material Testing in the Quality Control of SPF Experimental Mice

[Animal Modeling]-Application of Experimental Material Testing in the Quality Control of SPF Experimental Mice

To explore the feasibility and application value of testing materials for SPF experimental mouse barrier facilities...

2021-10-20
[Animal Modeling]-Genetic diversity of mouse resources and their genetic characteristics

[Animal Modeling]-Genetic diversity of mouse resources and their genetic characteristics

Establish a new type of mouse resource that reflects the characteristics of genetic diversity at the population level, and preliminarily explore its genetic characteristics...

2021-10-20
【Animal Modeling】-A study on active suspension of a magnetic fluid suspension ventricular assist device in vivo in experimental animals

【Animal Modeling】-A study on active suspension of a magnetic fluid suspension ventricular assist device in vivo in experimental animals

Magnetic fluid suspension ventricular assist device (hereinafter referred to as blood pump) actively shuts down in vivo experimental animal research, aimed at observing the reflux of blood after stopping the pump, the blood compatibility and biocompa...

2021-10-20
【Animal Modeling】-Study on Serum Metabonomics of Spontaneously Hypertensive Rats with Persistent Hypertension

【Animal Modeling】-Study on Serum Metabonomics of Spontaneously Hypertensive Rats with Persistent Hypertension

To investigate the changes of serum metabolites in spontaneously hypertensive rats (SHR) and the possible related mechanisms...

2021-10-20