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【Animal Modeling】-α-Mangostin on the immune function of immunosuppressive mice

【Animal Modeling】-α-Mangostin on the immune function of immunosuppressive mice

To explore the effect of α-mangostin on the immune function of cyclophosphamide-induced mouse immunosuppressive model, and provide experimental basis for subsequent mechanism research and the development of new drugs that increase immune function...

2021-09-19
【Animal Modeling】-an animal model of transformational preclinical pharmacological diseases

【Animal Modeling】-an animal model of transformational preclinical pharmacological diseases

The pathology of the eye is usually divided into different categories according to the affected area: ocular surface diseases, anterior and posterior diseases. Cataracts, age-related macular degeneration (AMD), glaucoma, presbyopia, dry eye (DED), ey...

2021-09-19
Therapeutic effect of rapamycin on primary sclerosing cholangitis induced by DDC in mice

Therapeutic effect of rapamycin on primary sclerosing cholangitis induced by DDC in mice

To explore the therapeutic effect of rapamycin on primary sclerosing cholangitis (PSC) in mice induced by 3,5-diethoxycarbonyl 1,4-dihydrocollidine (DDC), and explore its potential mechanism of action...

2021-09-19
Using genetic diversity mouse resources to screen CA16 pathogenicity-related genes

Using genetic diversity mouse resources to screen CA16 pathogenicity-related genes

Coxsackievirus A16 (Coxsackievirus A16, CA16) is one of the main pathogens of hand, foot and mouth disease, and its pathogenic mechanism is still unclear...

2021-09-19
【Animal Modeling】-Experimental Study on the Model of Focal Cerebral Ischemia in Balb/c Mice Made by Electrocoagulation

【Animal Modeling】-Experimental Study on the Model of Focal Cerebral Ischemia in Balb/c Mice Made by Electrocoagulation

Observe the feasibility of electrocoagulation on the middle cerebral artery in mice, and the feasibility of occluding the middle cerebral artery to establish a model of cerebral ischemia in mice...

2021-09-19
[Animal Modeling]-Construction of a Systemic Model of Parkinson\\

[Animal Modeling]-Construction of a Systemic Model of Parkinson

By applying behavioral and molecular imaging methods to dynamically evaluate the clinical characteristics of the cynomolgus monkey Parkinson\\\'s disease systemic model, providing stable and effective PD for preclinical studies of drugs, stem cells a...

2021-09-19
【Animal Modeling】-Levofloxacin-resistant mouse model

【Animal Modeling】-Levofloxacin-resistant mouse model

To detect the effect of low-concentration levofloxacin on the pneumonia model of Pseudomonas aeruginosa (PA) infection in mice, and to explore the method of levofloxacin resistance?...

2021-09-19
【Animal Modeling】-Aβ1-40 lateral ventricle injection to simulate Alzheimer\\

【Animal Modeling】-Aβ1-40 lateral ventricle injection to simulate Alzheimer

To analyze the brain imaging characteristics of tree shrews in Alzheimer\\\'s disease model...

2021-09-19
[Animal Modeling]-Application of Nile Red Tracer Nanoformulation in In vivo Imaging of Tumor-bearing Nude Mice

[Animal Modeling]-Application of Nile Red Tracer Nanoformulation in In vivo Imaging of Tumor-bearing Nude Mice

It is planned to wrap Nile Red in nano preparations and use its fluorescence characteristics to investigate the tumor targeting and tissue distribution of nano preparations in tumor-bearing mice...

2021-09-19
[Animal Modeling]-Observation of Neurotoxicity Effect of Flame Retardant TCPP Exposure on Mice and Related Mechanism Research

[Animal Modeling]-Observation of Neurotoxicity Effect of Flame Retardant TCPP Exposure on Mice and Related Mechanism Research

To investigate the neurotoxic effects of flame retardant TCPP exposure on mice and the study of related mechanisms...

2021-09-19
【Animal Modeling】-Using the seasonal influenza virus H3N2 mouse-adapted strain to establish a mouse model

【Animal Modeling】-Using the seasonal influenza virus H3N2 mouse-adapted strain to establish a mouse model

Use the seasonal influenza virus H3N2 mouse adaptive strain to establish a mouse model to explain the molecular mechanism of the pathogenic changes of the adaptive strain?...

2021-09-17
【Animal Modeling】-The effect of venous blood cell suspension storage time on blood routine measurement in mice

【Animal Modeling】-The effect of venous blood cell suspension storage time on blood routine measurement in mice

Observe the effect of venous blood cell suspension storage time on blood routine measurement in mice...

2021-09-17
[Animal modeling]-The effect of recombinant CC16 protein on the lung tissue structure and the expression of MMP-9 and TIMP-1 in mice with chronic obstructive pulmonary disease

[Animal modeling]-The effect of recombinant CC16 protein on the lung tissue structure and the expression of MMP-9 and TIMP-1 in mice with chronic obstructive pulmonary disease

To study the effect of recombinant rat CC16 (rCC16) protein on reducing lung tissue damage in a mouse model of chronic obstructive pulmonary disease, and on matrix metalloproteinase (MMP)-9 and tissue inhibitor of matrix metalloproteinase (TIMP)-1 in...

2021-09-17
【Animal Modeling】-Single intraosseous injection of simvastatin promotes normalization of breast cancer tumor blood vessels in mice

【Animal Modeling】-Single intraosseous injection of simvastatin promotes normalization of breast cancer tumor blood vessels in mice

To study the effect of a single intraosseous injection of simvastatin on the vascular structure and function of breast cancer tumors in mice...

2021-09-17
【Animal Modeling】-Induced endogenous infection mouse model through intestinal dissemination

【Animal Modeling】-Induced endogenous infection mouse model through intestinal dissemination

Establish a mouse model of intestinal disseminated endogenous infection, and provide a reliable experimental model for studying the association mechanism between intestinal flora and endogenous infection?...

2021-09-17
【Animal Modeling】-Acute and Chronic Intestinal Inflammation Animal Model

【Animal Modeling】-Acute and Chronic Intestinal Inflammation Animal Model

Inflammation animal model: The intestine is a highly complex organ requiring complex animal models to study its function and disease...

2021-09-17