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【Animal Modeling】-Two methods to prepare rabbit models of cardiac arrest

【Animal Modeling】-Two methods to prepare rabbit models of cardiac arrest

How to compare the characteristics of physiological indicators during cardiopulmonary resuscitation (CPR) in two rabbit models of potassium chloride-induced cardiac arrest and esophageal electrical chest wall tremor?...

2021-09-17
【Animal Modeling】-Gene knock-in mouse model of hypokalemic hypokalemic periodic paralysis

【Animal Modeling】-Gene knock-in mouse model of hypokalemic hypokalemic periodic paralysis

To establish a hypokalemic hypokalemic periodic paralysis model with gene knock-in CaV1.1-R528H mice and evaluate it...

2021-09-17
【Animal Modeling】-The common carotid artery puncture method to prepare the middle cerebral artery embolism model in rats

【Animal Modeling】-The common carotid artery puncture method to prepare the middle cerebral artery embolism model in rats

Comparison of the timeliness, success rate, and mortality of the rat middle cerebral artery embolization model prepared by the common carotid artery puncture method and the traditional suture method...

2021-09-17
【Animal Modeling】-Bioluminescence human liver cancer nude mouse model of carcinoma in situ

【Animal Modeling】-Bioluminescence human liver cancer nude mouse model of carcinoma in situ

How to select a human hepatocellular carcinoma cell line (HCCLM3-Luc) stably expressing the luciferase reporter gene to construct a nude mouse model of human hepatocarcinoma cell line carcinoma in situ?...

2021-09-17
【Animal Modeling】-The effect of Mac-1 gene deletion on the growth of melanoma

【Animal Modeling】-The effect of Mac-1 gene deletion on the growth of melanoma

To discuss the effect of Mac-1 deletion on the growth of melanoma tumors...

2021-09-17
【Animal Modeling】-Comparison of the difference between single staining and counter staining in observing the osteoarthritis slices of SIRT1 knockout mice

【Animal Modeling】-Comparison of the difference between single staining and counter staining in observing the osteoarthritis slices of SIRT1 knockout mice

A related mouse knee osteoarthritis model was established by SIRT1 gene knockout, and on this basis, the differences in the morphology of cartilage tissue slices observed by various separate staining or compound staining techniques were observed...

2021-09-17
【Animal Modeling】-The effect of vanadium exposure on the inflammatory response and migration of rat microglia

【Animal Modeling】-The effect of vanadium exposure on the inflammatory response and migration of rat microglia

To observe the effect of sodium metavanadate (NaVO3·2H2O) exposure on the inflammatory response and migration of microglia, and to discuss the related mechanisms of vanadium neurotoxicity...

2021-09-17
【Animal Modeling】-Pine pollen assisted paclitaxel combined with platinum-based chemotherapy to increase efficacy and reduce toxicity

【Animal Modeling】-Pine pollen assisted paclitaxel combined with platinum-based chemotherapy to increase efficacy and reduce toxicity

To study whether pine pollen has attenuating and enhancing effects on paclitaxel combined with platinum-based planned chemotherapy...

2021-09-17
【Animal Modeling】-Aging model of non-human primates

【Animal Modeling】-Aging model of non-human primates

Ideally, all biomedical research related to humans should be conducted on humans, but due to many ethical and technical considerations, this is obviously impractical...

2021-09-16
[Animal modeling]-Curcumin on acute kidney injury in rats with pregnancy-induced hypertension

[Animal modeling]-Curcumin on acute kidney injury in rats with pregnancy-induced hypertension

To explore the protective effect of curcumin on acute kidney injury induced by pregnancy-induced hypertension in rats and explore its potential mechanism...

2021-09-16
[Animal Modeling]-Modeling of human-derived adenomyosis in nude mice

[Animal Modeling]-Modeling of human-derived adenomyosis in nude mice

Establish a nude mouse human-derived adenomyosis model through different modeling methods, screen out ideal modeling methods, and provide an ideal animal model for studying the pathogenesis of adenomyosis and related treatment options...

2021-09-16
【Animal modeling】-animal model of lung adenocarcinoma brain metastasis

【Animal modeling】-animal model of lung adenocarcinoma brain metastasis

Use luc+-PC-9 human lung adenocarcinoma cells that stably express luciferase to establish a lung cancer brain metastasis animal model, compare bioluminescence imaging and 18F-FDG (18F-fluorodeoxyglucose, 18F-fluorodeoxyglucose) SPECT/CT in lung cance...

2021-09-16
[Animal modeling]-Resveratrol\'s inhibitory effect on rat blood hypercoagulability and its relationship with the expression of NF-κB

[Animal modeling]-Resveratrol's inhibitory effect on rat blood hypercoagulability and its relationship with the expression of NF-κB

To study the effect of resveratrol on the formation of blood hypercoagulability in rats and its relationship with the expression of NF-κB...

2021-09-15
【Animal Modeling】-The effect of high-fat diet on insulin resistance and the expression of liver insulin receptor substrates 1 and 2 in Tibet miniature pigs

【Animal Modeling】-The effect of high-fat diet on insulin resistance and the expression of liver insulin receptor substrates 1 and 2 in Tibet miniature pigs

Discuss the effect of high-fat diet on the expression of insulin resistance (IR) and hepatic insulin receptor substrates (IRS) 1 and 2 in Tibet miniature pigs...

2021-09-15
【Animal Modeling】-The Protective Effect and Mechanism of Pine Bark Extract on Cerebral Ischemia-Reperfusion Injury in Mice

【Animal Modeling】-The Protective Effect and Mechanism of Pine Bark Extract on Cerebral Ischemia-Reperfusion Injury in Mice

Discuss the neurotherapeutic effect and mechanism of IL-6/STAT3/miR-21 in pine bark extract on cerebral ischemia-reperfusion injury in mice...

2021-09-15
【Animal Modeling】-High-salt diet triggers cognitive deficits in the brains of mice

【Animal Modeling】-High-salt diet triggers cognitive deficits in the brains of mice

The \\\"heavy taste\\\" diet has become a daily choice for most people, but a study in mice published by American scientists on the 14th in the British journal \\\"Nature Neuroscience\\\" found that a high-salt diet can affect the...

2021-09-15