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【Animal Modeling】-Dynamic changes of blood physiological and biochemical indexes during the cultivation of diabetic inbred strains of gerbils

【Animal Modeling】-Dynamic changes of blood physiological and biochemical indexes during the cultivation of diabetic inbred strains of gerbils

To investigate the dynamic changes and regularities of blood physiological and biochemical indexes during the cultivation of diabetic inbred strains of gerbils...

2023-04-20
【Animal Modeling】-Experimental Dry Eye Rats

【Animal Modeling】-Experimental Dry Eye Rats

Establish and evaluate the dry eye model of rats, compare the morphological characteristics of the cornea and conjunctival epithelium of normal and dry eye rats...

2023-04-18
【Animal Modeling】-Aniline-induced DNA damage in mouse hepatocytes and lymphocytes and its repair effect

【Animal Modeling】-Aniline-induced DNA damage in mouse hepatocytes and lymphocytes and its repair effect

To study the genotoxicity of aniline and its repair kinetics...

2023-04-18
【Animal Modeling】-Preliminary Study on the Changes of Tongue Gene Expression Profile in Rats with Qi Stagnation and Blood Stasis Syndrome

【Animal Modeling】-Preliminary Study on the Changes of Tongue Gene Expression Profile in Rats with Qi Stagnation and Blood Stasis Syndrome

To study the changes of the whole gene expression profile in the tongue of rats with qi stagnation and blood stasis syndrome and the biological processes and pathways involved in differential genes by using gene chip technology, in order to provide s...

2023-04-12
【Animal Modeling】-Preparation and Evaluation of Cognitive Impairment Rat Model after Traumatic Brain Injury

【Animal Modeling】-Preparation and Evaluation of Cognitive Impairment Rat Model after Traumatic Brain Injury

To explore the preparation and evaluation of an animal model of cognitive impairment after traumatic brain injury...

2023-04-12
【Animal modeling】-The role of villin 1 in unilateral nephrectomy Habu nephritis mouse model

【Animal modeling】-The role of villin 1 in unilateral nephrectomy Habu nephritis mouse model

To investigate the similarities and differences between unilateral nephrectomy (UNX) mouse Habu nephritis model and normal mouse Habu nephritis model in renal function, renal pathological manifestations and glomerular villin 1 (VIL 1) expression and...

2023-04-12
【Animal modeling】-Intervention effect and mechanism of Exendin-4 on STZ-induced diabetic nephropathy in rats

【Animal modeling】-Intervention effect and mechanism of Exendin-4 on STZ-induced diabetic nephropathy in rats

To study the intervention effect and possible mechanism of Exendin-4 on streptozotocin-induced diabetic nephropathy in rats...

2023-04-11
【Animal Modeling】-Protective effect of camel milk on DSS-induced acute enteritis in mice

【Animal Modeling】-Protective effect of camel milk on DSS-induced acute enteritis in mice

To explore the protective effect of camel milk on dextran sulfate sodium (DSS)-induced acute enteritis in mice...

2023-04-11
【Animal Modeling】-Analysis of Intestinal Microorganisms in Miniature Pig Type 2 Diabetes Model

【Animal Modeling】-Analysis of Intestinal Microorganisms in Miniature Pig Type 2 Diabetes Model

Recent studies have shown that gut microbes are related to metabolic diseases such as type 2 diabetes mellitus (T2DM), and related mechanisms are mostly studied in rodents, but there are few reports on pig models that are more suitable for studying h...

2023-04-11
National Natural Hotspot: Super detailed! This article will help you easily understand DNA methylation [practical dry goods]

National Natural Hotspot: Super detailed! This article will help you easily understand DNA methylation [practical dry goods]

Today\\\'s short edition will introduce the natural hot spot of a country: DNA methylation. DNA methylation research has always been a multi hotspot of top journals, funding, clinical research, drug research, development and marketing...

2023-04-11
[Animal Modeling] - Su Jiacan/Chen Xiao/Jing Yingying Team Reveals Key Links in the Development of Osteoarthritis

[Animal Modeling] - Su Jiacan/Chen Xiao/Jing Yingying Team Reveals Key Links in the Development of Osteoarthritis

Osteoarthritis is a total joint disease characterized by degeneration of articular cartilage, abnormal remodeling of subchondral bone, osteophyte formation, and joint inflammation. The prevalence of knee osteoarthritis in people aged 65 and above is...

2023-04-10
【Animal modeling】-Metformin regulates the effect of miR-34a on airway inflammation in COPD rats

【Animal modeling】-Metformin regulates the effect of miR-34a on airway inflammation in COPD rats

To investigate the effect of metformin (Met)-regulated microRNA (miR)-34a on airway inflammation in rats with chronic obstructive pulmonary disease (COPD)...

2023-04-06
[Animal modeling] - Study on the mechanism of Herba Siegesbeckiae Tongshuan Capsule in alleviating cognitive function damage in rats with chronic cerebral ischemia

[Animal modeling] - Study on the mechanism of Herba Siegesbeckiae Tongshuan Capsule in alleviating cognitive function damage in rats with chronic cerebral ischemia

To study the effect of Siegesbeck Tongshuan capsule on the rat model of chronic cerebral ischemia and blood brain barrier...

2023-04-04
【Animal Modeling】-The effect of miR-328 on the expression of L-type calcium channel in thoracic aorta of hypertensive rats by exercise

【Animal Modeling】-The effect of miR-328 on the expression of L-type calcium channel in thoracic aorta of hypertensive rats by exercise

To investigate the promoting effect of microRNA-328 (miR-328) in improving the expression of L-type voltage-gated calcium channel in thoracic aortic smooth muscle cells of hypertensive rats by aerobic exercise...

2023-04-04
【Animal Modeling】-Establishment of a mentally dependent drug addiction model and the expression of Bax gene in the cerebellum

【Animal Modeling】-Establishment of a mentally dependent drug addiction model and the expression of Bax gene in the cerebellum

To study the effect of psychotropic drugs (heroin) on the expression of Bax gene in the cerebellum of addicted rats...

2023-04-04
【Animal modeling】-The expression characteristics of CD32 in rhesus monkey model of latent HIV infection

【Animal modeling】-The expression characteristics of CD32 in rhesus monkey model of latent HIV infection

To establish a rhesus monkey model of latent infection with SIVmac239, to study the expression characteristics of CD32 in resting, activated and/or memory CD4+ T cell subsets, and to analyze its potential as a marker of AIDS latent reservoir...

2023-04-04