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【Animal modeling】-Preparation and evaluation of MPTP-induced C57BL/6 mouse Parkinson\\

【Animal modeling】-Preparation and evaluation of MPTP-induced C57BL/6 mouse Parkinson

To establish a stable 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson\\\'s model in C57BL/6 mice, and to evaluate the model\\\'s behavior...

2023-04-03
【Animal Modeling】-Miniature Pig Obesity Model Induced by High Sugar and High Fat Feed

【Animal Modeling】-Miniature Pig Obesity Model Induced by High Sugar and High Fat Feed

To investigate the effect of high-fat and high-sugar diet on fat distribution and blood biochemical indexes in Bama miniature pigs...

2023-04-03
【Animal Modeling】-Effect of SEL1L gene deletion in central neurons on mouse behavior

【Animal Modeling】-Effect of SEL1L gene deletion in central neurons on mouse behavior

To explore the role of endoplasmic reticulum protein SEL1L in maintaining normal physiological activities of mammalian central nervous system...

2023-03-30
【Animal Modeling】-Application analysis of chloasma animal model based on data mining

【Animal Modeling】-Application analysis of chloasma animal model based on data mining

To analyze the application status of chloasma animal models, to lay a solid foundation for animal experiments for discussing the theoretical knowledge of chloasma, exploring new treatments, and developing new drugs, and to improve the scientificity,...

2023-03-29
【Animal modeling】-Effect of subsequent treatment of tannin cross-linking on bovine jugular vein blood vessels

【Animal modeling】-Effect of subsequent treatment of tannin cross-linking on bovine jugular vein blood vessels

To observe the effects of tannin fixation and subsequent treatment on improving the stability of tannin cross-linked bovine jugular vein storage solution, as well as on the thermal stability of blood vessels, anti-calcification ability, biomechanical...

2023-03-29
【Animal modeling】-The role of up-regulation of p-CaMKⅡ expression in dorsal root ganglion in rats with diabetic neuralgia

【Animal modeling】-The role of up-regulation of p-CaMKⅡ expression in dorsal root ganglion in rats with diabetic neuralgia

To observe the expression of phosphorylated calcineurin II (p-CaMK II) in the dorsal root ganglia of diabetic neuropathic pain model rats at different stages...

2023-03-29
【Animal Modeling】-Programmed freezing of hatched blastocysts and their dormant embryos in mice-Differential expression of Mgst1 gene before and after thawing

【Animal Modeling】-Programmed freezing of hatched blastocysts and their dormant embryos in mice-Differential expression of Mgst1 gene before and after thawing

To analyze the role of Mgst1 gene in programmed freezing of mouse embryos by comparing the relative expression of Mgst1 gene and the differential expression distribution of Mgst1 protein before and after programmed freezing and thawing of hatched bla...

2023-03-29
【Animal Model】-Continuous 5-day REM sleep deprivation induces delayed-onset depression-like behavior in mice

【Animal Model】-Continuous 5-day REM sleep deprivation induces delayed-onset depression-like behavior in mice

To investigate the effect of continuous long-term rapid eye movement sleep deprivation (5 d) on depression-like behavior and the level of amygdala monoamine oxidase A in C57BL/6J mice...

2023-03-24
【Animal modeling】-Mechanism of jujube saponins alleviating Alzheimer\\

【Animal modeling】-Mechanism of jujube saponins alleviating Alzheimer

To investigate the mechanism of jujube saponin (ZSS) alleviating sevoflurane anesthesia in 9-month-old APP/PS1/tau triple transgenic Alzheimer\\\'s disease model mice...

2023-03-24
【Animal Modeling】-Effect of geranin on meconium-induced acute lung injury in neonatal rats and its mechanism

【Animal Modeling】-Effect of geranin on meconium-induced acute lung injury in neonatal rats and its mechanism

To investigate the effect of geranin on meconium-induced acute lung injury in neonatal rats and its molecular mechanism...

2023-03-24
【Animal Modeling】-Comparative Study of Three Surgical Rat Models of Extrahepatic Cholestasis

【Animal Modeling】-Comparative Study of Three Surgical Rat Models of Extrahepatic Cholestasis

To evaluate the advantages and disadvantages of three surgical methods for extrahepatic cholestasis model in rats using serology, imaging and pathology...

2023-03-24
【Animal modeling】-Effect of microcystin-LR on mitochondrial function of mouse primary hepatocytes

【Animal modeling】-Effect of microcystin-LR on mitochondrial function of mouse primary hepatocytes

Microcystin pollution caused by cyanobacterial blooms is one of the world\\\'s concerns...

2023-03-24
【Animal modeling】-Analysis of the localization and expression of vitamin D receptor in the duodenum of C57BL/6 mice

【Animal modeling】-Analysis of the localization and expression of vitamin D receptor in the duodenum of C57BL/6 mice

To investigate the localization and expression of vitamin D receptors in the duodenum of C57BL/6 mice, and to study the correlation between vitamin D system and intestinal development...

2023-03-23
【Animal Modeling】-Observation of Pulse Wave Velocity and Arterial Wall Structure in Spontaneously Hypertensive Rats of Different Ages

【Animal Modeling】-Observation of Pulse Wave Velocity and Arterial Wall Structure in Spontaneously Hypertensive Rats of Different Ages

By measuring the pulse wave velocity (PWV) of spontaneously hypertensive rats (SHR) at different ages, and analyzing the structure of aortic media cross-sectional area (MCSA) of SHR at the same time, reveal the physiological changes of blood vessels...

2023-03-23
[Animal Modeling]-Effect of Human Umbilical Cord Mesenchymal Stem Cells on Autophagy in the Hippocampus of Naturally Aging Rats

[Animal Modeling]-Effect of Human Umbilical Cord Mesenchymal Stem Cells on Autophagy in the Hippocampus of Naturally Aging Rats

In this study, human umbilical cord mesenchymal stem cell transplantation can improve the decline of learning, memory and cognitive ability in naturally aging rats by regulating the level of autophagy. The research is feasible...

2023-03-23
【Animal Modeling】- Improvement of the method of preventing the displacement of the implanted dilator in the sarcoma and deep fascia of the experimental rabbit

【Animal Modeling】- Improvement of the method of preventing the displacement of the implanted dilator in the sarcoma and deep fascia of the experimental rabbit

To investigate the method of preventing the displacement of the implanted dilator in the sarcoid and deep fascia of rabbits...

2023-03-23