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How to prepare animal model of naphthalene cataract?

How to prepare animal model of naphthalene cataract?

Naphthalene can increase the reactive oxygen species in rabbit cells, increase the generation of free radicals, and increase the peroxidation damage, resulting in damage to the lipid of the lens cell membrane and causing experimental cataracts...

2020-08-03
【Animal model】-induced diabetic retinopathy

【Animal model】-induced diabetic retinopathy

In diabetes, the retina is exposed to high concentrations of plasma glucose. Free glucose accumulates in cells and activates aldose reductase, which is the main enzyme for sorbitol metabolism, promotes sorbitol production, and stimulates retinal capi...

2020-08-03
How to prepare animal model of induced retinitis pigmentosa?

How to prepare animal model of induced retinitis pigmentosa?

Induction of retinal diseases, drugs or physical methods are used to change the structure of the retina, resulting in a disease similar to human retinitis pigmentosa. The operation of the animal model of RP disease induced by physical and chemical fa...

2020-08-03
[Animal model]-Spontaneous hereditary retinitis pigmentosa RCS rat model

[Animal model]-Spontaneous hereditary retinitis pigmentosa RCS rat model

The Royal College of Surgeons (RCS) rat is an animal model of autosomal recessive inheritance. CS rat retinal pigment epithelial cells (retinal pigment epithelium, RPE) express genes that cannot swallow discrete patches. This leads to the loss of pho...

2020-08-03
How to prepare an animal model of dry eye disease?

How to prepare an animal model of dry eye disease?

Dry eye disease, also known as dry cornea and conjunctiva, is one of the most common diseases in ophthalmology. It can cause ocular surface damage or impaired vision and affect the quality of life of patients. At present, in most patients, the cause ...

2020-08-03
How to prepare animal models of viral keratitis?

How to prepare animal models of viral keratitis?

Viral keratitis (viral keratitis) is the most common herpes simplex keratitis (HSK)...

2020-08-03
How to prepare an animal model of acute epilepsy?

How to prepare an animal model of acute epilepsy?

Acute epilepsy models are usually acute epileptic seizure models that can induce epilepsy with one treatment, including maximum electric shock (MES) epilepsy models and pentylenetetrazol (PTZ) epilepsy models...

2020-08-03
How to prepare the AD animal model related to aging?

How to prepare the AD animal model related to aging?

AD mainly affects the elderly and is a disease associated with aging. Aging plays an important role in the pathogenesis of AD. This type of model regards aging as the cause of AD, and uses various methods and means to promote animal aging, including ...

2020-08-03
[Animal model]-Spontaneous SLE mouse model

[Animal model]-Spontaneous SLE mouse model

ZB/BINJ mice suffer from hemolytic anemia, increased immunoglobulin content, and autoimmune abnormalities, such as anti-nuclear antibodies, anti-DNA antibodies, and anti-thymic antibodies. Immune complex glomerulonephritis; ZW/LacJ mice are usually n...

2020-08-03
【Animal model】-SLE rabbit model induced by allogeneic hepatic cytoplasmic protein

【Animal model】-SLE rabbit model induced by allogeneic hepatic cytoplasmic protein

Immune rabbits with allogeneic hepatocyte protein, and induce various autoantibodies, abnormal renal function and proteinuria. It is similar to the clinical manifestations of human SLE...

2020-08-03
【Animal model】-Activated lymphocytes and their chromatin induce SLE mouse model

【Animal model】-Activated lymphocytes and their chromatin induce SLE mouse model

The lymphocytes of activated inbred mice can be used as antigens to immunize the same mice so that the host can produce its own anti-dsDNA antibodies, anti-nuclear antibodies, etc....

2020-08-03
How to prepare animal models of spontaneous leukemia?

How to prepare animal models of spontaneous leukemia?

AKR spontaneous leukemia mice are born with carcinogenic RNA viruses, and their response to drug treatment is similar to childhood acute lymphoblastic leukemia (ALL)...

2020-08-03
How to prepare animal model of aplastic anemia?

How to prepare animal model of aplastic anemia?

Aplastic anemia (aplastic anemia) usually refers to the primary myelogenetic syndrome of unknown cause. It mainly manifests as low bone marrow production, pancytopenia, anemia, bleeding and infection...

2020-08-03
How to prepare animal model of hemorrhagic anemia?

How to prepare animal model of hemorrhagic anemia?

Anemia after acute hemorrhage is anemia caused by rapid heavy bleeding, while anemia after chronic hemorrhage is small cell anemia caused by long-term moderate bleeding....

2020-08-03
How to prepare an animal model of hemolytic anemia?

How to prepare an animal model of hemolytic anemia?

Róngxiě xìng pínxiě (HA) shì yī zhǒng chángjiàn de pínxiě lèixíng, tā dǎozhì hóngxìbāo cúnhuó shíjiān jiào duǎn, bìngqiě yóuyú mǒu zhǒng yuányīn ér bèi pòhuài, chāochūle gǔsuǐ de bǔcháng nénglì, tā shì yī zhǒng chángjiàn de zàoxiě jíbìng. 70/5000 H...

2020-08-03
How to prepare animal models of ischemic anemia?

How to prepare animal models of ischemic anemia?

Iron deficiency anemia (Ironemia anemia, IDA) refers to iron deficiency caused by various reasons and anemia caused by a decrease in red blood cells. IDA is the most common anemia, and its incidence is significantly higher in infants and women of chi...

2020-08-03