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【Animal Modeling】-Exploring the effect of stress on appetite in rats from the brain-stomach ghrelin pathway

【Animal Modeling】-Exploring the effect of stress on appetite in rats from the brain-stomach ghrelin pathway

To study the molecular mechanism of stress affecting appetite from the brain ghrelin pathway...

2022-06-22
【Animal Model】-Effect of α-mangostin on the immune function of immunosuppressed mice

【Animal Model】-Effect of α-mangostin on the immune function of immunosuppressed mice

To investigate the effect of α-mangostin on the immune function of cyclophosphamide-induced immunosuppression in mice, and to provide experimental basis for the follow-up mechanism research and the development of new drugs to increase immune function...

2022-06-22
【Animal modeling】-Protective effect of curcumin on acute kidney injury in pregnant hypertensive rats

【Animal modeling】-Protective effect of curcumin on acute kidney injury in pregnant hypertensive rats

To investigate the protective effect of curcumin on acute kidney injury induced by gestational hypertension in rats and explore its potential mechanism...

2022-06-22
【Animal Modeling】-Experimental Study on Lung Tissue Injury Induced by Dental Grinding Dust in Rats

【Animal Modeling】-Experimental Study on Lung Tissue Injury Induced by Dental Grinding Dust in Rats

To evaluate the effects of three kinds of dental grinding dusts of cobalt-chromium-molybdenum metal (trade name: Vitaline), zirconium dioxide porcelain and polymethyl methacrylate resin on lung tissue injury in rats...

2022-06-22
【Animal modeling】-Effect of Naoshuantong capsule on the expression of inflammatory factors in aorta of ApoE-/- mice

【Animal modeling】-Effect of Naoshuantong capsule on the expression of inflammatory factors in aorta of ApoE-/- mice

To observe the effect of Naoshuantong capsule on the expression of inflammatory related factors interleukin-1β, interleukin-6, tumor necrosis factor, intercellular adhesion molecule-1 and metalloproteinase-9 in ApoE-/- atherosclerosis mouse model. Th...

2022-06-22
【Animal Modeling】-VEGF-A Inhibitor sFLT-1 Improves Renal Function in Type 1 Diabetic Mice

【Animal Modeling】-VEGF-A Inhibitor sFLT-1 Improves Renal Function in Type 1 Diabetic Mice

To investigate whether the VEGF-A inhibitor sFLT-1 can reverse the renal damage in type 1 diabetic mice by inhibiting the activation and inflammatory response of vascular endothelial cells...

2022-06-22
【Animal Modeling】-Hydrogen peroxide-induced changes in isolated rat uterine ligament fibroblasts

【Animal Modeling】-Hydrogen peroxide-induced changes in isolated rat uterine ligament fibroblasts

To investigate the effect and possible mechanism of oxidative stress on the proliferation, apoptosis, collagen synthesis and inflammatory factor expression of uterine ligament fibroblasts...

2022-06-22
【Animal Modeling】-Effect of two-color coreopsis alcohol extract on intestinal flora of type 2 diabetic mice

【Animal Modeling】-Effect of two-color coreopsis alcohol extract on intestinal flora of type 2 diabetic mice

To explore the possible link between the alcoholic extract of coreopsis bicolor, intestinal flora and type 2 diabetes mellitus...

2022-06-21
【Animal modeling】-Effect of curcumin on glucose transport and PI3K/Akt signaling pathway in adipocytes of type 2 diabetic rats

【Animal modeling】-Effect of curcumin on glucose transport and PI3K/Akt signaling pathway in adipocytes of type 2 diabetic rats

To investigate the effect of curcumin on glucose transport and phosphatidylinositol kinase-3 (PI3K)/protein kinase B (Akt) signaling pathway in adipocytes of type 2 diabetes mellitus (T2DM) rats...

2022-06-21
【Animal modeling】-Polymorphism analysis of PPARγ2 gene promoter in Wuzhishan miniature pigs

【Animal modeling】-Polymorphism analysis of PPARγ2 gene promoter in Wuzhishan miniature pigs

To analyze the polymorphisms in the regulatory region of the PPARγ2 gene promoter in Wuzhishan miniature pigs...

2022-06-21
【Animal Modeling】-Changes and Significance of Arterial Blood Gas Analysis in Rats with Chronic Hypoxic Pulmonary Hypertension

【Animal Modeling】-Changes and Significance of Arterial Blood Gas Analysis in Rats with Chronic Hypoxic Pulmonary Hypertension

To investigate the changes and significance of arterial blood gas analysis indexes in a rat model of hypoxic pulmonary hypertension induced by chronic hypoxia...

2022-06-21
【Animal Modeling】-FoxO3A Gene Knockout Mice Breeding Identification and Primary Analysis of Bone Marrow Hematopoietic Stem Cell Phenotype

【Animal Modeling】-FoxO3A Gene Knockout Mice Breeding Identification and Primary Analysis of Bone Marrow Hematopoietic Stem Cell Phenotype

To breed and identify FOXO3A knockout mice. The selected FOXO3A knockout heterozygous mice were used for breeding, and the homozygous mice were used for experiments...

2022-06-21
【Animal Modeling】-Expression of Perilipin in Kidney Tissue of Rats with Diabetic Nephropathy

【Animal Modeling】-Expression of Perilipin in Kidney Tissue of Rats with Diabetic Nephropathy

To observe the characteristics of rat diabetic nephropathy model and the diagnostic value of urinary LN for early DN, and to explore the expression of perilipin (Plin) in the kidneys of DN rats...

2022-06-21
【Animal Modeling】-Establishment and application of real-time PCR detection method for mouse cytomegalovirus

【Animal Modeling】-Establishment and application of real-time PCR detection method for mouse cytomegalovirus

To establish a fluorescent quantitative PCR method for mouse cytomegalovirus and make a preliminary application...

2022-06-21
【Animal modeling】-Effect of alprostadil on eIF2α/ATF4/CHOP pathway and liver function in fulminant liver failure rats

【Animal modeling】-Effect of alprostadil on eIF2α/ATF4/CHOP pathway and liver function in fulminant liver failure rats

To investigate the effect of alprostadil (PGE1) on liver function in rats with fulminant liver failure (FHF), and to investigate its effect on eukaryotic translation initiation factor 2α (eIF2α) / activating transcription factor 4 (ATF4) / C/ EBP Reg...

2022-06-20
【Animal modeling】-Effect of salidroside on Nrf2/Keap1 signaling pathway and wound healing in diabetic foot ulcer rats

【Animal modeling】-Effect of salidroside on Nrf2/Keap1 signaling pathway and wound healing in diabetic foot ulcer rats

To investigate the effect of salidroside (Sal) on nuclear transcription factor E2-related factor 2 / Kelch-like epichlorohydrin-related protein 1 (Nrf2 / Keap1) signaling pathway and wound healing in diabetic foot ulcer (DFU) rats...

2022-06-20